1.Clinical outcomes of permanent stenting with endoscopic ultrasound gallbladder drainage
Eisuke SUZUKI ; Yuji FUJITA ; Kunihiro HOSONO ; Yuji KOYAMA ; Seitaro TSUJINO ; Takuma TERATANI ; Atsushi NAKAJIMA ; Nobuyuki MATSUHASHI
Clinical Endoscopy 2023;56(5):650-657
Background/Aims:
Endoscopic ultrasound gallbladder drainage (EUS-GBD) is gaining attention as a treatment method for cholecystitis. However, only a few studies have assessed the outcomes of permanent stenting with EUS-GBD. Therefore, we evaluated the clinical outcomes of permanent stenting using EUS-GBD.
Methods:
This was a retrospective, single-center cohort study. The criteria for EUS-GBD at our institution are a high risk for surgery, inability to perform surgery owing to poor performance status, and inability to obtain consent for emergency surgery. EUS-GBD was performed using a 7-Fr double-pigtail plastic stent with a dilating device. The primary outcomes were the recurrence-free rate of cholecystitis and the late-stage complication-avoidance rate. Secondary outcomes were technical success, clinical success, and procedural adverse events.
Results:
A total of 41 patients were included in the analysis. The median follow-up period was 168 (range, 10–1,238) days. The recurrence-free and late-stage complication-avoidance rates during the follow-up period were 95% (38 cases) and 90% (36 cases), respectively. There were only two cases of cholecystitis recurrence during the study period.
Conclusions
EUS-GBD using double-pigtail plastic stent was safe and effective with few complications, even in the long term, in patients with acute cholecystitis.
2.Activities to Learn The Importance of Advance Care Planning from The Perspective of Emergency Medicine
Nobuyuki UCHIDA ; Yoko SHIMAMURA ; Akiko NAKAMURA ; Tetsuya HOSHINO ; Toru MARUHASHI ; Toshihiro NAKAJIMA ; Keiichi YAMADA ; Shouichi SAITOU ; Akira SUNOHARA
An Official Journal of the Japan Primary Care Association 2020;43(2):70-72
3.Exploring the Factors That Influence Pain Relief and Bone-marrow Suppression When Strontium Chloride Is Administrated
Kin-ichi OKUBO ; Kouichi TANABE ; Nozomu MURAKAMI ; Hiroyasu SEKI ; Kazuhiro NAKAJIMA ; Nobuyuki GOTO ; Fumiko OHTSU
Palliative Care Research 2018;13(1):23-29
Aim: The usefulness and safety of strontium chloride (89Sr), a radiopharmaceutical agent for painful bone metastasis, varies from patient to patient, but the reasons for why the usefulness and safety vary have not been elucidated. The purpose of this study is to explore the background factors of patients who experienced pain relief or bone-marrow suppression after 89Sr was administrated. Methods: In the cases of pain relief, we divided the results from a numeric rating scale (NRS) before and after 89Sr administration into effective and ineffective groups as outcomes. In the cases of bone-marrow suppression, we analyzed neutrophil cells, blood platelets, and hemoglobin levels, respectively, before and after 89Sr administration as outcomes. Then, we performed statistical analyses on both case groups. Results: The results showed that the background factors associated with pain relief were weight, the 89Sr dosage amount, NRS, eGFR, SCr, and Ca levels before 89Sr administration and the area of bone metastasis (number of sites reached). We found that background factors associated with bone-marrow suppression have a moderate significant correlation with hemoglobin, NRS, and SCr levels before 89Sr administration after investigating factors which influence neutropenia. In the case of thrombocytopenia, there was a moderate significant correlation with platelet counts before 89Sr administration. In the case of hypochromia, there was a moderate significant correlation with hemoglobin levels before 89Sr administration. Discussion: Our study could elucidate patient background factors associated with pain relief and bone-marrow suppression after 89Sr administration.
4.Feasibility of Endoscopic Papillary Large Balloon Dilation in Patients with Difficult Bile Duct Stones without Dilatation of the Lower Part of the Extrahepatic Bile Duct.
Yuji FUJITA ; Akito IWASAKI ; Takamitsu SATO ; Toshio FUJISAWA ; Yusuke SEKINO ; Kunihiro HOSONO ; Nobuyuki MATSUHASHI ; Kentaro SAKAMAKI ; Atsushi NAKAJIMA ; Kensuke KUBOTA
Gut and Liver 2017;11(1):149-155
BACKGROUND/AIMS: There is no consensus for using endoscopic papillary large balloon dilation (EPLBD) in patients without dilatation of the lower part of the bile duct (DLBD). We evaluated the feasibility and safety of EPLBD for the removal of difficult bile duct stones (diameter ≥10 mm) in patients without DLBD. METHODS: We retrospectively reviewed the records of 209 patients who underwent EPLBD for the removal of bile duct stones from October 2009 to July 2014. Primary outcomes were the clearance rate and additional mechanical lithotripsy. Secondary outcomes were the incidence of complications and recurrence rate. RESULTS: Fifty-seven patients had DLBD (27.3%), and 152 did not have DLBD (72.7%). There were no significant differences in the overall success rate or the use of mechanical lithotripsy. Success rate during the first session and procedure time were better in the DLBD than the without-DLBD group (75.7% vs 66.7%, 48.1±23.0 minutes vs 58.4±31.7 minutes, respectively). As for complications, there were no significant differences in the incidence of pancreatitis, perforation or bleeding after endoscopic retrograde cholangiopancreatography. The recurrence rate did not differ significantly between the two groups. CONCLUSIONS: EPLBD is a useful and safe method for common bile duct stone removal in patients without DLBD.
Bile Ducts*
;
Bile Ducts, Extrahepatic*
;
Bile*
;
Cholangiopancreatography, Endoscopic Retrograde
;
Common Bile Duct
;
Consensus
;
Dilatation*
;
Hemorrhage
;
Humans
;
Incidence
;
Lithotripsy
;
Methods
;
Pancreatitis
;
Recurrence
;
Retrospective Studies
5.Result and Current Status of Medical and Dental Cooperation in Rural Core Hospital without a Dental Department
Nobuyuki Uchida ; Yoko Shiba ; Hiroki Hirakata ; Osamu Shimamura ; Masayoshi Kanbe ; Momoko Ohokubo ; Miyuki IIzuka ; Yoshie Nakajima
An Official Journal of the Japan Primary Care Association 2017;40(1):16-20
Aims: To verify the significance of medical and dental cooperation over the past 10 years in Haramachi Red Cross hospital, which does not have a dental department. We will also investigate the situation of inpatients' oral cavities in our hospital. From these results, we will discuss future activities about medical and dental cooperation.
Methods: We analyzed questionnaire and the field survey data related to medical and dental cooperation. We also compared the current oral assessments by a dentist and the past assessments without a dentist.
Results: A dental hygienist has participated in NST (Nutrition Support Team) rounds at our hospital since 2005. From then, we started oral assessments for inpatients and we recommend for patients to visit a dentist before surgery or chemotherapy. Furthermore, we have held oral care seminars for medical staff. As a result, medical staff have demonstrated an improvement in awareness and technique for oral care. Since 2013, a dentist from the Agatsumagun Dental Association has started oral assessments for preoperative inpatients at our hospital. However, we found that the frequency of problems in their oral cavities and that of postoperative pneumonia have not decreased.
Conclusion: Medical and dental cooperation is effective for our hospital. We think that it is important not only to promote medical and dental cooperation, but also to perform a dental checkup and educate the general population on periodontal disease.
6.Finger Lifting Resternotomy Technique
Akihiko Yamauchi ; Satoshi Muraki ; Yasuko Miyaki ; Kazutoshi Tachibana ; Mayuko Uehara ; Masaki Tabuchi ; Tomohiro Nakajima ; Yousuke Yanase ; Nobuyuki Takagi ; Tetsuya Higami
Japanese Journal of Cardiovascular Surgery 2011;40(6):269-271
We describe a novel method for repeat median sternotomy. We have successfully used ‘finger’ lifting resternotomy technique and achieved zero major cardiovascular injury/catastrophic hemorrhage events at reoperation. After general anesthesia, all patients were placed in the supine position and two external defibrillator pads were placed on the chest wall. We perform a median skin and subcutaneous incision along the previous sternotomy incision extending 3 cm distal to the sternum. The sternal wires that had been used for the previous closure were left in place but untied. Using a long electric cautery, right thoracotomy was performed under the right costal arch approach. Then, the operator could approximate the sternal wires in the retro-sternal space. At the same time, the operator could confirm the retro-sternal adhesion status which by touching with a finger. Resternotomy was performed using an oscillating saw pointed toward the operator's finger, which allowed safe re-median sternotomy from the lower to the upper part of the sternum. This technique of finger-lifting resternotomy has been employed in 50 cardiovascular reoperations and resulted in 0 incident of major cardiac injury or catastrophic hemorrhage. The finger-lifting resternotomy technique is safe and simple in reoperation procedures and yield excellent early outcomes.
7.Successful Treatment of a Chronic Pulmonary Thromboembolism Associated with Right Atrial Thrombus, Atrial Fibrillation and Tricuspid Insufficiency
Hiroshi Iida ; Yoshio Sudo ; Hideo Ukita ; Masahisa Masuda ; Nobuyuki Nakajima
Japanese Journal of Cardiovascular Surgery 2007;36(1):41-44
We describe an unusual case of a chronic pulmonary thromboembolism with right atrial thrombus. A 56-year-old man suffering from chronic pulmonary thromboembolism for 5 years complained of increasing dyspnea. Computed tomography revealed massive emboli in bilateral pulmonary arteries and a thrombus in the right atrium. Massive tricuspid regurgitation and atrial fibrillation were also recognized. We performed pulmonary thromboendarterectomy using a Jamieson rigid long miniature sucker with a rounded tip and our original flexible sucker under deep hypothermic circulatory arrest. Right atrial thrombectomy, tricuspid annuloplasty and a Maze procedure were also performed during the cooling, recirculating, and warming period. His postoperative cause was uneventful, and he was able to return to an ordinary lifestyle without acquiring oxygen inhalation. Tricuspid annuloplasty and Maze operation during pulmonary thromboendarterectomy contributed to the maintenance of stable homodynamics during and after surgery.
8.A Giant Right Atrial Myxoma with Lung Carcinoma Detected by Syncope
Hirofumi Nishida ; Yoshio Sudou ; Hideo Ukita ; Nobuyuki Nakajima
Japanese Journal of Cardiovascular Surgery 2005;34(2):140-143
A 75-year-old man was referred to our hospital with dyspnea on effort, recurrent attacks of loss of consciousness and abnormal shadow on chest X-ray film. Computed tomographic scan confirmed a 1.5×2.0cm mass with slight spiculation in the right lower lobe (S6) and revealed an ovoid right atrial mass. Transthoracic echocardiography showed that the giant mass which filled most of the right atrium had no mobility. Coronary angiography revealed clusters of new vessels which originated from the atrial branches of the circumflex coronary artery. A T1-weighted MRI scan demonstrated that the mass was isointense relative to the adjacent myocardium. We considered that performing cardiac surgery prior to pulmonary resection, as in a staged procedure, would have advantages in morbidity. We first performed removal of the right atrial tumor which was a 6.8×5.5×4.5cm shiny mass attached to the interatrial septum. Histological examination of the mass confirmed the diagnosis of cardiac myxoma. Three months later, right S6 segmentectomy was carried out using thoracoscopy and the tumor was finally diagnosed as squamous cell carcinoma. We have followed the patient for about 10 months after the first operation and there is no evidence of tumor recurrence and no more syncopic attacks.
9.A Modified Procedure Using Branched Graft as Inflow for Leg Revascularization in a Case of Acute Type A Aortic Dissection Complicated with Leg Ischemia
Shigeyasu Takeuchi ; Hisanori Fujita ; Nobuyuki Nakajima
Japanese Journal of Cardiovascular Surgery 2004;33(3):213-215
A 32-year-old man with severe back pain and cold, pulseless bilateral lower extremities was admitted. Enhanced CT scan revealed acute type A aortic dissection and the true lumen was severely compressed or occluded at the level of the abdominal aorta. Emergency simultaneous graft replacement of the ascending aorta and aortic arch was performed under deep hypothermic circulatory arrest, antegrade selective cerebral perfusion in addition to the elephant trunk technique. Although distal anastomosis was constructed only to the true lumen, leg ischemia persisted. Therefore, a new modified procedure applying a branched graft used for antegrade systemic perfusion as inflow and conventional axillo-bifemoral bypass graft was anastomosed to restore adequate circulation to the lower extremities. In the treatment of acute type A aortic dissection complicated with leg ischemia, the modified technique we employed is a simple and feasible method for leg revascularization in cases in which malperfusion to the leg persists in spite of complete of aortic repair.
10.A Case of Cardiac Infiltrating Lipoma in the Interatrial Septum
Hirofumi Nishida ; Yoshio Sudou ; Hideo Ukita ; Nobuyuki Nakajima
Japanese Journal of Cardiovascular Surgery 2004;33(5):329-332
A 75-year-old woman presented with chest pain on exertion. Cardiac catheterization revealed double vessel coronary artery disease. Echocardiographic examination showed the presence of an abnormal mass in the interatrial septum without any flow velocity signal within the mass. She was scheduled for elective coronary artery bypass grafting. The lesion appeared as a homogeneous mass on CT scan, with an attenuation coefficient of -122 Hounsfield units, suggestive of lipoma. A T1-weighted MRI scan demonstrated that the signal intensity of the interatrial mass corresponded to that of fatty tissue. On surgery with cardiopulmonary bypass a large mass was found to involve the right atrial wall, the interatrial sulcus and the interatrial septum. The mass could not be resected completely, because it adhered strongly to the septal myocardium. On histological examination, the tumor was composed of mature fatty tissues, was not encapsulated and was diagnosed as infiltrating lipoma. The postoperative course was uneventful. CT, MR imaging and color Doppler ultrasonography were very useful in making a tissue-specific diagnosis.


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