1.Vibration sensation associated with motor function has specific frequency characteristics in community-dwelling older Japanese adults
Daisuke HASEGAWA ; Norio HOTTA ; Takashi MIZUTA ; Masahiro HOGURO ; Kaoru TODA
Japanese Journal of Physical Fitness and Sports Medicine 2023;72(4):305-313
Vibration sensation is related to motor function. However, it is unclear which vibration frequencies are associated with motor function. Therefore, in this cross-sectional study, we investigated whether a specific frequency of vibration sensation could explain motor functions. Thirty-two community-dwelling Japanese healthy older adults aged 70 years or older participated in the present study. Grip strength, one-leg standing time, and 10-m walking time were evaluated as indicators of motor function. Vibratory (40, 128, and 256 Hz) and tactile sensory tests were examined as sensory functions. Grip strength per body weight was significantly correlated with sex, body mass index, falls efficacy scale, vibration sensation with 40 and 128 Hz, and 10-m walking time (P < 0.05). Furthermore, one-leg standing time showed a correlation between vibration sensation (128 and 256 Hz) and fall history (P < 0.05). However, 10-m walking time was significantly correlated with only the grip strength to body weight ratio. Multiple regression analysis showed that vibration sensation with 128 Hz (β = 0.427) and sex (β = -0.335) (P < 0.05) were significant independent variables associated with grip strength to body weight ratio. Vibration sensation with 256 Hz (β = 0.465) and age (β = -0.343) (P < 0.05) were significant independent variable associated with one-leg standing time. No significant variables were identified for the 10-m walking time. Vibration sensation associated with motor function shows specific frequency characteristics in community-dwelling older Japanese adults.
2.Effect of snack eating on sensitive salivary stress markers cortisol and chromogranin A.
Masahiro TODA ; Kanehisa MORIMOTO ; Shingo NAGASAWA ; Kazuyuki KITAMURA
Environmental Health and Preventive Medicine 2004;9(1):27-29
OBJECTIVESTo investigate the effect of snack eating on salivary cortisol and chromogranin A (CgA).
METHODSFrom 14∶00 to 18∶00, starting two hours after consumption of a midday meal, saliva samples were collected every 30 minutes from 15 healthy males, 7 of whom (snack group) ate a snack immediately after the sampling at 15∶00. Salivary cortisol and CgA levels were determined by ELISA. Samples were controlled according to salivary flow rates.
RESULTSFor the snack group, after snack consumption, salivary cortisol increased to exceed significance (p<0.05) at 15∶30 and rose even higher at 16∶00. In the control group, there was no such change. There was no significant change in salivary CgA in either the snack group or the control groups during the sampling period.
CONCLUSIONSThese findings suggest that no food should be consumed for at least 90 mins before saliva sampling for cortisol determination and that salivary CgA is probably not affected by snack eating.
3.Application of specific brain function evaluation by optical topography.
Akiko OBATA ; Kanehisa MORIMOTO ; Tatsuya TAKESHITA ; Yuriko ISSHIKI ; Masahiro TODA
Environmental Health and Preventive Medicine 2003;8(1):29-32
OBJECTIVESTo use the evaluation of a specific brain function obtained by optical topography. This system uses a non invasive method to measure brain function unlike other major systems.
METHODSTwelve optical fibers were attached to the subject's head. Hemodynamic changes in the motor cortex were measured during finger tapping before and after alcohol intake for eachALDH2 genotype.
RESULTSDifferent hemodynamic changes in the motor cortex were observed among, theALDH2 genotypes.
CONCLUSIONSOptical topography is a useful tool for evaluating specific brain functions. Further research is needed on the relations between various environmental factors and brain functions by optical topography.
4.Beneficial effect of tomato juice drinking on anti-mutagenicity of saliva.
Masahiro TODA ; Kanehisa MORIMOTO ; Sei-Ichi NAKAMURA
Environmental Health and Preventive Medicine 2003;7(6):289-291
OBJECTIVESThe purpose of this study was to investigate the effect of tomato juice drinking on the antimutagenicity of saliva.
METHODSSubjects were 22 healthy male university students. They were divided into tomato group and control group. The tomato group drank tomato juice for 10 days. The anti-mutagenicity of saliva was measured using the umu test.
RESULTSIn the tomato group, there was a significant increase in the inhibiting capacity of saliva on the mutagenicity of AF-2 after tomato juice drinking for 10 days. This increase was, however, temporary. In the control group, there was no such change in the inhibiting capacity of saliva.
CONCLUSIONSThese findings suggest the significant effect of tomato juice drinking on the anti-mutagenicity of saliva. In addition, lycopene may have played an important role in its mechanism.
5.Correlation between saliva glycated and blood glycated proteins.
Ichiro NAKAMOTO ; Kanehisa MORIMOTO ; Tatsuya TAKESHITA ; Masahiro TODA
Environmental Health and Preventive Medicine 2003;8(3):95-99
OBJECTIVESBlood and saliva samples were obtained to examine if there is a correlation between saliva glycated protein and blood glycated protein.
METHODSBlood and saliva samples of 51 male workers were collected. The fructosamine and hydrazine methods were used to measure saliva glycated protein. HbA1c, fructosamine and blood glucose were measured as indices of blood glycated protein, and the correlation between blood glycated protein and saliva glycated protein was examined.
RESULTSSaliva fructosamine glycated protein showed a significant correlation with HbA1c and blood glucose (r=0.449; p=0.001 and r=0.445; p=0.001, respectively). No correlation was identified between saliva hydrazine glycated protein and the index of blood glycated protein.
CONCLUSIONSBlood glycated protein and blood glucose could be estimated by measuring saliva glycated protein.
6.Application of Specific Brain Function Evaluation by Optical Topography
Akiko OBATA ; Kanehisa MORIMOTO ; Tatsuya TAKESHITA ; Yuriko ISSHIKI ; Masahiro TODA
Environmental Health and Preventive Medicine 2003;8(1):29-32
Objectives: To use the evaluation of a specific brain function obtained by optical topography. This system uses a non invasive method to measure brain function, unlike other major systems. Methods: Twelve optical fibers were attached to the subject's head. Hemodynamic changes in the motor cortex were measured during finger tapping before and after alcohol intake for each ALDH2 genotype. Results: Different hemodynamic changes in the motor cortex were observed among the ALDH2 genotypes. Conclusions: Optical topography is a useful tool for evaluating specific brain functions. Further research is needed on the relations between various environmental factors and brain functions by optical topography.
brain function
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seconds
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Landscapes
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Pulmonary evaluation
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Function
7.A further note on the sampling device for the anti-mutagenicity of saliva.
Masahiro TODA ; Kanehisa MORIMOTO ; Sei-Ichi NAKAMURA ; Kazuo HAYAKAWA
Environmental Health and Preventive Medicine 2002;7(1):27-29
OBJECTIVESThe purpose of this study was to compare the anti-mutagenicity of Salivette and test-tube sampling saliva. In addition, the relation between the inhibiting and pH-buffering capacities of saliva was investigated.
METHODSSubjects were 52 healthy female university students. The collection of saliva samples was carried out using 2 sampling devices; test-tube and Salivette. The anti-mutegenicity of the saliva was measured using the umu test.
RESULTSThe inhibiting capacity of Salivette-saliva was significantly lower compared with that of testube-saliva (p<0.01,t test). However, there was a significant correlation between them (r=0.35; p<0.05). In addition, there was a significant correlation between the inhibiting and pH-buffering capacities of saliva (r=-0.36; p<0.05).
CONCLUSIONSThese findings suggest that both the Salivette and the test-tube may be appropriate as saliva-sampling devices. In addition, they suggest that the bicarbonates might inhibit the anti-mutagenicity of saliva, or that the activity of substances related to the anti-mutagenicity of saliva might be dependent on pH.
8.Daily lifestyles and anti-mutagenicity of saliva.
Masahiro TODA ; Kanehisa MORIMOTO ; Sei-Ichi NAKAMURA ; Kazuo HAYAKAWA
Environmental Health and Preventive Medicine 2002;7(1):11-14
OBJECTIVESThe purpose of this study was to investigate the relation between lifestyle and the antimutagenicity of saliva.
METHODSSubjects were 52 healthy female university students. The collection of the saliva samples and the lifestyle measurements were carried out for them. The anti-mutagenicity of the saliva was measured using the umu test.
RESULTSWith regard to the lifestyle items, only "nutrient balance" tended to contribute positively to the inhibiting capacity of the saliva on the mutagenicity of AF-2. In addition, there was a significant inverse correlation between the score of 7 other items and the inhibiting capacity of the saliva (r=-0.32; p<0.05). We also found a significant relation between their tea and/or coffee consumption and the inhibiting capacity of the saliva.
CONCLUSIONSThese findings suggest that the inhibiting capacity of saliva worked to decrease mutagen levels that were enhanced by poor lifestyle. In addition, "nutrient balance" may contribute to the inhibiting capacity of the saliva independent of 7 other items. With regard to the tea and/or coffee consumption. further studies should be carried out.
9.Lifestyle, mental health status and salivary secretion rates.
Masahiro TODA ; Kanehisa MORIMOTO ; Sanae FUKUDA ; Kazuo HAYAKAWA
Environmental Health and Preventive Medicine 2002;6(4):260-263
The relations between salivary variables, lifestyle and mental health status were investigated for 61 healthy female university students. The salivary secretion rates were significantly higher in the good lifestyle groups compared with the poor lifestyle groups. Among the 8 lifestyle items tested. "eating breakfast" and "mental stress" were significantly related to the salivary secretion rates. The present findings suggest that the acquisition of a good lifestyle is also very important from the viewpoint of the prevention of oral disease.A highly significant correlation (r=0.97; p<0.01) between the salivary cortisol levels and the cortisol secretion rates when controlled for the salivary secretion rates was also observed. This suggests that there is a high correlation between the intact salivary cortisol levels and the total cortisol quantity per unit time. Therefore, both these values can be used as a good index for the salivary cortisol determination.
10.Beneficial Effect of Tomato Juice Drinking on Anti-Mutagenicity of Saliva
Masahiro TODA ; Kanehisa MORIMOTO ; Sei-ichi NAKAMURA
Environmental Health and Preventive Medicine 2002;7(6):289-291
Objectives: The purpose of this study was to investigate the effect of tomato juice drinking on the anti-mutagenicity of saliva. Methods: Subjects were 22 healthy male university students. They were divided into tomato group and control group. The tomato group drank tomato juice for 10 days. The anti-mutagenicity of saliva was measured using the umu test. Results: In the tomato group, there was a significant increase in the inhibiting capacity of saliva on the mutagenicity of AF-2 after tomato juice drinking for 10 days. This increase was, however, temporary. In the control group, there was no such change in the inhibiting capacity of saliva. Conclusions: These findings suggest the significant effect of tomato juice drinking on the anti-mutagenicity of saliva. In addition, lycopene may have played an important role in its mechanism.
Tomatoes
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Saliva
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Alcohol consumption
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g <3>
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Drinking function


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