1.A Case of Coronary Artery Bypass Grafting for Unstable Angina with Acromegaly.
Mitsuhiro Yamamura ; Takashi Miyamoto ; Katsuhiko Yamashita ; Toshihiko Saga ; Hideki Yao ; Takashi Yasuoka ; Kazushige Inoue ; Hirokazu Minamimura ; Torazo Wada ; Masahiro Kawanaka
Japanese Journal of Cardiovascular Surgery 1998;27(2):100-103
A 65-year-old woman was admitted with a diagnosis of unstable angina after PTCA. She was diagnosed with acromegaly 8 years ago. She underwent an emergency coronary artery bypass grafting (LITA-LAD, SVG-HL-Cx). Serum growth hormone (GH) levels were 65.5ng/ml (normal limit<5ng/ml) before the operation. During a cardiopulmonary bypass GH levels elevated to 92.7ng/ml, but decreased to 15.9ng/ml after the operation. After 3 postoperative days GH levels increased gradually again and blood sugar levels became unstable. Finally it was necessary to increase the dose of bromocriptine. To our knowledge, there are only a few patients who have undergone coronary artery bypass grafting associated with acromegaly. This case suggests it is important to control GH levels at the operation and during the postoperative period.
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