1.Workplace stress level study regarding the some health factors
Otgonbaatar D ; Lkhagvasuren Ts ; Naranbaatar N ; Munkhkhand J
Mongolian Medical Sciences 2020;192(2):45-50
		                        		
		                        			Background:
		                        			Over the past 20 years, world wide scale social and economic reforms, technological breakthroughs, 
and the population growth (increased by 1.64 billion), especially in urban areas, have had a negative 
impact on human health; changes in living and working conditions (environmental and air pollution), 
population density, traffic jam, unhealthy lifestyles, workload, and work stress – all contribute to non-communicable diseases – are increasing. According to researchers from Stanford University in the 
United States, “Stress plays a key role in the development of behavioral disorders such as poor diet, 
lack of exercise, alcohol and tobacco use, and addiction. Furthermore, these behavioral disorders 
play a major role in the development of metabolic disorders and cancer, such as hypertension, 
cardiovascular disease such as myocardial infarction, and diabetes and obesity. “Stress, in particular, 
depends on the type of workplace, work environment, and occupation in which the person spends 
most of their life.
		                        		
		                        			Materials and Methods:
		                        			The study is covered 473 nurses from the specialized tertiary level hospitals in Mongolia. We 
determined their perceived work stress by the WPS (3 parts 57 questions) questionnaire of American 
scientist Rice. The work stress results were analytically analyzed with the cross-sectional method 
regarding the nurses’ arterial blood pressure. 
		                        		
		                        			Results:
		                        			Totally 473, or 121, 89, 146, and 117 nurses participated from NCTO (1), NCMH (3), NCID (4), and 
NCC (4). In present study, 34 or 7.2% of 18-24 year olds, 139 or 29.4% of 25-30 year olds, 99 or 
20.9% of 31-40 year olds, 169 or 35.7% of 41-50, and 32 or 6.8% over 51 year olds. The study was 
conducted by collecting an age group similar to the age pyramid of nurses working in the hospital. 
The participants illustrated low levels of work stress in 7.6%, medium levels in 27.1%, and high levels 
of work stress in 65.3%, respectively. When we examine whether the level of stress exposure of 
nurses differs between the groups by high, medium, and low levels of workplace stress, the analysis 
of one factor variance confirms the statistical real difference (F = 3.071), (p = 0.028). 
The study results revealed that long lasted accumulated work stress trigger the hypertention. 
		                        		
		                        			Conclusion
		                        			The onset of stress in a nurse’s workplace depends on many different social factors, 
such as age, gender, organizational characteristics, organization, place of work, and years of 
experiences. In conclusion, we agreed with Spruil Tanya et al., that chroronic stress at work can be 
the reason for the high blood pressure.
		                        		
		                        		
		                        		
		                        	
2.Risk factors and biomarkers of infection after Caesarean section
Narantsatsralt D ; Munkhbilguun A ; Erkhembaatar T ; Lkhagvasuren J ; Naran G
Mongolian Medical Sciences 2019;190(4):8-13
		                        		
		                        			Background:
		                        			The WHO recommends the ideal rate for cesarean section to be 15% of the total birth, but researchers 
are still attracting attention to the fact that in recent years this rate has been steadily increasing, and 
risk is not decreasing worldwide. Incidence of postcesarean section inflammation and infection are 
8-10 times higher than vaginal birth. The determination of lactate levels in early diagnosis of sepsis is 
clinically significant and the higher the lactate level increases the risk of mortality. 
		                        		
		                        			Objective:
		                        			The aim of the study is to improve early detection of inflammation and infection and prevention of 
serious complications by using risk factors of postcesarean section inflammation and infection, and 
detecting procalcitonin and lactate in maternal blood.
		                        		
		                        			Materials and Methods:
		                        			This research is conducted between 2015-2017 based at the “Urguu” Maternity Hospital, Obstetric 
Clinic of National Center for Maternal and Child Health of Mongolia. Factors affecting postcesarean 
section inflammation and infection are calculated based on multifactorial regression analysis. 
Procalcitonin was determined by enzyme binding assay while lactate, C-reactive protein, and lactate 
dehydrogenase were determined by “E-311” the fully automated analyzer.
		                        		
		                        			Results:
		                        			According to the results of the study, the probability of inflammatory and infectious complication 
is 2.4% when the duration of labor increases by one unit, 34.8% when the risk of amniotic fluid 
increases, 14.6% when the pregnancy process become more complicated. Whereas, excessive fetal 
weight statistically increases the risk of infection, but its impact is low. The result of the study shows 
that the procalcitonin sensitivity was 65%, and the specificity was 96%. Lactate resulted in sensitivity 
of 56%, but with only 67% specificity. C-reactive protein had a sensitivity of 65% and a specificity of 
96%. Lactate dehydrogenase resulted in sensitivity of 95%, and specificity of 82% in the diagnosis 
of sepsis. 
		                        		
		                        			Conclusion
		                        			Postterm pregnancy, premature rupture of membranes, multifetal pregnancy, prolonged labor, 
placenta previa, pyelonephritis, chronic hepatitis, chronic hypertensive disorder, anemia, emergency 
cesarean section, preeclampsia are risk factors and it is statistically significant at (P<0.0001). The 
biomarkers have a direct correlation to all stages of inflammation and infections, which are important 
for the diagnosis.
		                        		
		                        		
		                        		
		                        	
3.A comparative study on the fertility of uterine artery embolization and myomectomy for leiomyoma
Uranchimeg R ; Ganbaatar R ; Bayarmaa L ; Enkhtsetseg J ; Lkhagvasuren J
Mongolian Medical Sciences 2017;181(3):20-24
		                        		
		                        			Objective:
		                        			To compare the nature of pregnancy and deliveryin women with leiomyoma who were treated with uterine 
artery embolization to the outcomes in women who were treated with abdominal myomectomy. 
		                        		
		                        			Material and Methods:
		                        			A prospective, clinical study was conducted in 2010-2013 at “Urguu” Maternity Hospital, Ulaanbaatar. 94 
women meeting the criteria were selected for the study. Post-treatment, the patients were reviewed for a 
period of two years. Uterine artery embolization was performed using polyvinyl alcohol particles (300-500 
µm in diameter).
		                        		
		                        			Results:
		                        			The percentage of conception in UAE group was 25.5% and 31.9% in myomectomy group (p=0.494); 
complication of pregnancy was 50.0% and 57.1% respectively (p=0.729); complication of delivery was 
33.3% and 0.0% respectively (p=0.047). 88.9% and 90.0% (p=0.596) had Caesarean delivery. 16 (84.2%) 
women had uncomplicated and 3 (15.8%) women had complicated delivery due to placenta praevia, 
placenta acreta and uterine hypotonia. These cases all belonged to UAE group. 
		                        		
		                        			Conclusion
		                        			Pregnancy rates in women with leiomyoma who were treated by uterine artery embolization, 
compared with pregnancies after abdominal myomectomy, were similar.(p=0.494) In this study, there 
was the rate of Cesarean delivery above 80 percent in both group. There were no differences in newborn 
weights and Apgar scores.
		                        		
		                        		
		                        		
		                        	
4. RISK FACTORS RELATED TO SEPSIS ASSOCIATED FROM CESAREAN SECTION
Narantsatsralt D ; Erkhembaatar T ; Lkhagvasuren J
Innovation 2015;9(3):36-40
		                        		
		                        			
		                        			 One of the important problems in obstetricians science is wound infection following cesarean deliveries.It occurs in 2-10%.In the obstetricians practice these disorders decline associated with the use of antibiotics but the last 10 years all countries of the world puerperal infection increases, obstetric causes sepsis purulent difficulties of 150 thousand women deaths per year. Objective: To identify risk factories for wound infection following cesarean delivery.A population – based study. To comparing women who have and have not developed a wound infection prior to discharge from First maternity hospital, Mother and Child National health Centre of Ulaanbaatar, between 2011-2013.Using a logistic regression model, the following risk factors were identified: Sepsis purulent difficulties were more likely to develop in women who have twin pregnancy (OR=4.5; 95% CI 2.4-8.6) and vaginal exam multiple times (OR=6.7; 95% CI 2.1-22). No significant differences between the 2 group who underwent cesarean delivery for indications such as induction of labor, falled induction of labor, presence of meconium – stained amniotic fluid, nonreassuring fetal heart rate patterns. Sepsis purulent difficulties (p=0.001) occurred more often in women who were older, multiple pregnancy and delivery, pre-eclampsia, emergency cesarean delivery. The risk to develop sepsis purulent difficulties following cesarean delivery is maternal age, pregnancy, recurrent abortion, gestation age, emergency cesarean delivery, premature rupture of membranes, twin pregnancy and labor complication. (p=0.001) 
		                        		
		                        		
		                        		
		                        	
5.Contemporary treatment guidelines for managing вenign uterine tumors
Uranchimeg R ; Ganbaatar R ; Bayarmaa L ; Lkhagvasuren J
Mongolian Medical Sciences 2015;172(2):115-122
		                        		
		                        			
		                        			 Uterine leiomyomas are common (20-50%) in women of reproductive age. It is a benign tumor and it ranks second place among genital organ disorders in women.To date, abdominal laparotomy and laparoscopic surgical treatment (myomectomy and hysterectomy) are widely used to manage symptomatic leiomyomas.Although, hysterectomy is considered to be a radical method to manage uterine leiomyomas, women who have had hysterectomy are left totally infertile and they also are at risk to develop post-surgical and post-anesthetic complications. The advantage of myomectomy is to preserve women’s fertility and menstrual function but, the probability of recurrence of leiomyoma is 15-30% [1, 2]. Furthermore, depending on the location, size and number of fibroids, duration of surgery lingers, volume of blood loss is high and the risk to develop post surgical adhesions are high too.In recent, more than a decade period, effective and minimally invasive new, non-surgical methods to manage uterine leiomyomas have been introduced in many countries around the world. These methods have short recovery period and are advantageous to women to preserve their reproductive organ and fertility. They include: uterine artery embolization, uterine artery occlusion via transvaginal route and MRI– guided focused ultrasound surgery of uterine fibroids. Antiprogesterone-low-dose mifepristone for uterine leiomyomas are being introduced as well.In our country, managing leiomyomas surgically is still occupying high rate among surgical treatments. Further, to prevent and reduce complications of surgical treatment and to preserve organ, it is essential and imperative to introduce some of the above- mentioned contemporary non-surgical methods. 
		                        		
		                        		
		                        		
		                        	
6.The Causes of sepsis after Caesaråan section and determination of antibiotic sensitivity
Narantsatsralt D ; Lkhagvasuren J ; Naran G
Mongolian Medical Sciences 2015;174(4):25-29
		                        		
		                        			
		                        			 Background. Puerperal infection following caesarean section remains a major cause of maternalmorbidity and mortality. It is still one of actual problems in Obstetrics and has incidence rate 2-10%. It isestimated 150 000 maternal deaths due to infection worldwide, despite tendency to decline septicemiaafter C-section due to wide usage of antibiotics in the obstetric practice, postpartum infection hasincreased last decade. Post-Caesarean sepsis incidence rate is above 20%. An assortment of pathologicagents may cause puerperal infection including bacteria, virus and parasites. In 30-40s of last centurymain reason of infection was Streptococcus, then in 40-60s major role was played by Staphylococcus,later in 70-80s Gram-Negative Aerobic Bacteria took its place.Objective. To improve prevention and treatment of post-caesarean sepsis by detection of its causes andantibiotic sensitivity. Materials and methods: We reviewed patients admitted to First Maternity Hospitaland National Center for Maternal and Child Health and who had post-caesarean sepsis between 2011-2013. Statistics analysis had been performed by SPSS-17 software programme, whereas statisticsprocess by X2 test, Fisher test, and t-test. Confi rmation rate was 95%. P<0, 05.Results. The clinical course of 361 post-caesarean patients with septicemia was reviewed prospectively.Primary dysfunctional labour (P<0.033), preterm rupture of the membranes (P<0.0001), ineffectivelabour induction (P<0.001) are risk factors for infectious morbidity. Considerations should be given toprophylactic antibiotic therapy by choosing correct medicine at the correct time. E.coli 29,4%, Intestinalbacteria 9,1%, Staphylococcus epidermis’s 8,9%, Staphylococcus aureus 7,2%, Gram-NegativeBacteria 6,6%, Streptococcus 5,3%, Gram-Positive Bacteria 2,8%, Candida albicans 1,4%, Micoplasma1,1% were responsible for bacteremia, respectively.Conclusion. Bacteriology of all patients diagnosed with post-caesarean sepsis in 74, 7% was positivefor pathologic bacterial cultures. Infection caused by 1 bacteria in 141 cases (39, 1%), by 2 bacteria in 56cases (15, 5%), by 3 bacteria in 2 cases (0, 6%), without any detection of bacteria 162 cases (44, 9%). 
		                        		
		                        		
		                        		
		                        	
7. Correlation between the blood glucose level and food consumption of Elder people
Ariunjargal Z ; Zesemdorj O ; Erdenebat N ; Odsuren S ; Bat-Erdene N ; Lkhagvasuren TS ; Munkhtsetseg J ; Munkhzol M ; Odkhuu E
Innovation 2014;8(2):28-32
		                        		
		                        			
		                        			 The increasing proportions of aged persons have been accompanied in the world. NCDs are often associated with older age groups. High blood glucose levels and unhealthy diet increase the risk of or cause most NCDs. In this study we aimed to determine correlation between the older people (60<) blood glucose level and food consumption. 1563 healthy elder people participated in this research. We measured blood glucose level in all subjects at the Nursing school’s Training and Research Center of health science university of Mongolia. Ulaanbaatar city, Orkhon aimag, Khovd aimag, Khentii aimag, Bulgan aimag, Dornogovi aimag, Tov aimags represented urban areas, while the rest of aimags and soums represented rural areas. The questionnaire was used to collect data on respondent’s social-economic status, fruit and vegetable consumption, physical activity, and their causes. In order to assess the diet pattern of the surveyed population, the respondents were asked about frequency of fruit and vegetable consumption, type of oil used in food, and amount of salt consumed daily. Simple regression analysis was performed to shown that significantly positive correlations between blood glucose and salt intake (р<0.001), The other composition are no significantly changes. 
		                        		
		                        		
		                        		
		                        	
8.Pregnancy cases after embolization of uterine fibroids
Uranchimeg R ; Ganbaatar R ; Bayarmaa L ; Lkhagvasuren J
Mongolian Medical Sciences 2014;168(2):43-48
		                        		
		                        			
		                        			 INTRODUCTION:Uterine leiomyoma occurs with broad range of 20-50% among reproductive aged women. It takessecond place of all women’s genital diseases that cause abnormal menstrual bleeding. Leiomyomadependent surgical frequency such as hysterectomy is around up to 80, 6%. Lately uterine fibroidembolization treatment is highly effective, less painful, and more rapid recovery, most importantlykeeping organ while maintaining the reproductivity, is successfully entered in practice. We successfullyperformed 40 cases first time in Mongolia and 8 of them conceived naturally after treatment.GOAL:To determine if arterial embolization in women with uterine fibroids (leiomyomata) is an effectivemethod to keep their reproductive organ intact.OBJECTIVES:• To study pregnancy cases in women who had uterine fibroid embolization• To monitor and determine the features of course of pregnancy and childbirth.• To evaluate uterine fibroids.MATERIALS AND METHODS:The study was conducted in 2009-2012. A total of forty women between 23-50 years of age,diagnosed with symptomatic uterine fibroid that received embolization treatment of dominatingarterial blood vessel feeding the uterine fibroids were involved in the study. Eight of the forty womenwho conceived naturally were selected for the study. The study focused on monitoring the course oftheir pregnancy and delivery and its outcome.RESULTS:Among 40 women who underwent bilateral uterine artery embolization, 31 (75.5%) were seeking tobecome pregnant, and 8 of the 31 (25, 8%) became pregnant, four having been nulliparous. Onepatient had two pregnancies. All 8 pregnancies were spontaneous. The mean time from embolizationto conception was 12±3, 5 months (range, 6-27 months). Three medical terminations occurred. Theother 5 pregnancies went to term; one pregnancy had to be terminated pre-term due to placentapraevia. 60% experienced threatened abortion and 1 case with advanced age mother complicatedwith mild preeclampsia. 62,5% of the women’s pregnancy ended with childbirth, of which one woman(20%) had vaginal delivery and the remaining four pregnancies (80%) ended with C-section. On anaverage, post-treated uterine fibroids decreased in volume by 94% in comparison to pre-treateduterine fibroids in the patients who became pregnant. All of the neonates were healthy with Apgarscores greater than8. The mean weight of the neonates was 3,189± 200 g (range, 2,100–3,800 g). One neonate waspreterm due to placenta praevia (2,100 g).CONCLUSION:1. Of the forty women that received arterial embolization treatment with uterine fibroid, thirty one(75, 5%) women desired to keep their uterine for further reproduction, of which eight women (25,8% of the patients) between the ages of 23-42 years (mean age=35) conceived naturally. Arterialembolization to treat women with uterine fibroids is an effective method for women who wish to keeptheir reproductive organ intact to conceive and reproduce.2. 60 percent of the women who conceived experienced threatened abortion and 20 percent of thewomen’s pregnancy had to be terminated pre-term due to placenta praevia. 62,5 percent of thewomen’s pregnancy ended with childbirth, of which one woman (20%) had vaginal delivery and theremaining four pregnancies (80%) ended with C-section.3. On an average, post-treated uterine fibroids decreased in volume by 94% in comparison to pretreateduterine fibroids. 
		                        		
		                        		
		                        		
		                        	
9.Study on the association between general surgeon volume, professional skill and surgery outcome
Janchiv J ; Lkhagvasuren TS ; Tseden P ; Sergelen O
Mongolian Medical Sciences 2014;170(4):49-54
		                        		
		                        			
		                        			 Background: Several researchers had been previously done the health professional workload study,however, because of the lack of studies of the relationship between physicians’ volume and outcome, wedid not have enough evidence of the resource allocation, the surgery outcome and quality improvementin our country.Goal: The study was aimed to study general surgeon volume and surgery outcome.Materials and Methods: We randomly selected 1147 patients diagnosed with gallbladder disease whounderwent laparoscopic cholecystectomy (LC) and acute appendicitis from 2012-2013 at the First andThird Clinical hospital and Khovd province Regional Diagnostic and Treatment Center were included.Patient demographics and clinical information, such as drug cost, duration of surgery, and name ofsurgeons were derived from patient medical records. Surgeons’ information, such as age, gender,professional and academic degree, and work experience were derived from hospital human resourcedepartment and correlation analysis was performed to examine the association between surgeryduration, surgeon experience and drug cost.Results: Hospitals LC was done 51,3±32,8 minutes with 24900,70 tugriks, appendectomy was done52,7±31,4 minutes with 18361,00 tugriks of drug cost. The Third Clinical hospital surgeons operatedhigher costs (28631,34±16985,86tugriks) and shorter time (39,86±39,54 ìèí) of an appendectomy. Butthe First Clinical hospital surgeons incurred lower cost (8460,82±13231,40 tugriks) of appendectomy.However, there were no significant differences in operation time and drug average cost in appendectomyin terms of positive and weak correlation(r<0.5, p>0.05). Conclusion: General surgeon volume was notassociated with surgery outcome. 
		                        		
		                        		
		                        		
		                        	
10.Current trend of preventive antibiotic administration during the caesarean delivery
Narantsatsralt D ; Lkhagvasuren J ; Naran N
Mongolian Medical Sciences 2014;170(4):84-89
		                        		
		                        			
		                        			 Caesarean delivery is frequently complicated by surgical site infections, endometritis and urinary tractinfection. Most surgical site infections occur after discharge from the hospital and increasingly beingused as performance indicators. Worldwide, the rate of caesarean delivery is increasing. Evidencebasedguidelines recommended the use of prophylactic antibiotics before surgical incision. An exceptionis made for caesarean delivery, where narrow-range antibiotics are administered after umbilical cordclamping because of putative neonatal benefit. However, recent evidence supports the use of pre-incision,broad-spectrum antibiotics, which result in a lower rate of maternal morbidity with no disadvantage tothe neonate. The beneficial effect of prophylactic antibiotics in reducing the occurrence of infectiousmorbidity form caesarean section, whether elective or emergency is well established. A single dose offirst-generation cephalosporin is as effective as multiple doses of broad-spectrum agents. Prophylacticantibiotics for caesarean section are commonly used worldwide, and in most institutions a single dose isadministered, generally after clamping of the umbilical cord. However, a recent survey (published in 2011)of maternal and fetal medicine physicians in the USA revealed that 84% of those who responded (theresponse rate was 25%) used preoperative administration. The effectiveness of prophylactic antibioticsdepends on their presence in effective concentrations throughout the operative period. Classen et al.found that administration of prophylactic antibiotics within a 2-hour period preoperatively was associatedwith the lowest surgical wound infection rate. Because of concerns about unnecessary fetal exposure,masking of fetal infection, increases in neonatal septic work-up and the emergence of resistant strainswhen prophylactic antibiotics are given preoperatively, it is a common obstetric practice to administerprophylactic antibiotics after cord clamping.Conclusion:1. Probability for occurring wound infection happens in case of urgent caesarean delivery for patientswho have not administered by preventative antibiotic.2. It has been confirmed that preventative antibiotic administration is proper in special occasions ofcaesarean delivery for women who suffer from anaemia obesity, diabetes, or chronic inflammatorydisease prior to their delivery.3. When preventative antibiotic administration is used 60 minutes before the caesarean delivery,concentration in blood and tissue reaches up to the maximum amount. 
		                        		
		                        		
		                        		
		                        	
            
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