2.Postoperative Radiographic Early-Onset Adjacent Segment Degeneration after Single-Level L4–L5 Posterior Lumbar Interbody Fusion in Patients without Preoperative Severe Sagittal Spinal Imbalance
Yuji MATSUOKA ; Kenji ENDO ; Hidekazu SUZUKI ; Yasunobu SAWAJI ; Hirosuke NISHIMURA ; Taichiro TAKAMATSU ; Osamu KOJIMA ; Kazuma MURATA ; Takeshi SEKI ; Shinji HORIE ; Takamitsu KONISHI ; Kengo YAMAMOTO
Asian Spine Journal 2018;12(4):743-748
		                        		
		                        			
		                        			STUDY DESIGN: Retrospective study. PURPOSE: To investigate the relationship between preoperative total spinal sagittal alignment and the early onset of adjacent segment degeneration (ASD) after single-level posterior lumbar interbody fusion (PLIF) in patients with normal sagittal spinal alignment. OVERVIEW OF LITERATURE: Postoperative early-onset ASD is one of the complications after L4–L5 PLIF, a common surgical procedure for lumbar degenerative disease in patents without severe sagittal imbalance. A better understanding of the preoperative characteristics of total spinal sagittal alignment associated with early-onset ASD could help prevent the condition. METHODS: The study included 70 consecutive patients diagnosed with lumbar degenerative disease who underwent single-level L4–L5 PLIF between 2011 and 2015. They were divided into two groups based on the radiographic progression of L3–L4 degeneration after 1-year follow-up: the ASD and the non-ASD (NASD) group. The following radiographic parameters were preoperatively and postoperatively measured: sagittal vertebral axis (SVA), thoracic kyphosis (TK), lumbar lordosis, pelvic tilt, and pelvic incidence (PI). RESULTS: Eight of the 70 patients (11%) experienced ASD after PLIF (three males and five females; age, 64.4±7.7 years). The NASD group comprised 20 males and 42 females (age, 67.7±9.3 years). Six patients of the ASD group showed decreased L3–L4 disc height, one had L3–L4 local kyphosis, and one showed both changes. Preoperative SVA, PI, and TK were significantly smaller in the ASD group than in the NASD group (p <0.05). CONCLUSIONS: A preoperative small SVA and TK with small PI were the characteristic alignments for the risk of early-onset ASD in patients without preoperative severe sagittal spinal imbalance undergoing L4–L5 single-level PLIF.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Kyphosis
		                        			;
		                        		
		                        			Lordosis
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Retrospective Studies
		                        			
		                        		
		                        	
3.Gait Analysis in Cervical Spondylotic Myelopathy.
Hirosuke NISHIMURA ; Kenji ENDO ; Hidekazu SUZUKI ; Hidetoshi TANAKA ; Takaaki SHISHIDO ; Kengo YAMAMOTO
Asian Spine Journal 2015;9(3):321-326
		                        		
		                        			
		                        			STUDY DESIGN: Gait analysis of patients with cervical spondylotic myelopathy (CSM) by using a sheet-type gait analysis system. PURPOSE: The aim of this study was to compare the gait patterns of patients with CSM, evaluated by the Nurick grades, and to determine the threshold values of gait parameters predicting the occurrence of a fall by using a gait recorder. OVERVIEW OF LITERATURE: Gait disorder due to CSM may progress to severe paraplegia, following even a minor trauma such as a fall. The indications for the surgery of CSM without severe paralysis remain controversial. The quantitative gait analysis and the decision for decompressive surgery in patients with CSM are important in order to prevent severe paraplegia from a fall. METHODS: One hundred thirty-two subjects (normal, 34; CSM, 98) underwent gait analysis by using a sensor sheet. Measurements of gait cycle parameters included the step and stride length, step width, foot angle, swing phase, and stance phase. CSM was assessed by Nurick grade. RESULTS: Although the clinical symptoms were lacking, Nurick grade 1 had significant abnormalities in the parameters of velocity, step length, and step angle (p<0.05). Regarding the Nurick grade and walking phase, the length of the stance phase was increased to more than 70% of the entire walking cycle in Nurick grade 4. CONCLUSIONS: Gait analysis was an objective tool for evaluating the gait stability. Our results suggested that when the percentage of the stance phase in the gait cycle increases to above 70%, the CSM patients have an increased fall risk.
		                        		
		                        		
		                        		
		                        			Foot
		                        			;
		                        		
		                        			Gait*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Movement Disorders
		                        			;
		                        		
		                        			Paralysis
		                        			;
		                        		
		                        			Paraplegia
		                        			;
		                        		
		                        			Physical Examination
		                        			;
		                        		
		                        			Spinal Cord Diseases*
		                        			;
		                        		
		                        			Walking
		                        			
		                        		
		                        	
4.An Inflammatory Pseudotumor Arising from the Mitral Valve
Shigeto Miyasaka ; Keisuke Morimoto ; Kengo Nishimura ; Yoshikazu Fujiwara
Japanese Journal of Cardiovascular Surgery 2015;44(4):184-187
		                        		
		                        			
		                        			We herein report a rare case of an inflammatory pseudotumor arising from the mitral valve. A 58-year-old man who was undergoing maintenance dialysis was referred to us due to the presence of a tumor mass attached to the mitral valve. It was asymptomatic and had been coincidentally found by echocardiography. The tumor mass was a sphere measuring about 1 cm in size, and it arose from the posterior mitral leaflet. A myxoma of the left atrium was suspected, and the tumor mass was resected along with part of the posterior leaflet by means of a right minithoracotomy (MICS). The tumor was postoperatively diagnosed to be an inflammatory pseudotumor based on the findings of a histopathological examination. During the follow-up period of 1 year and 2 months after surgery, there was no recurrence. An inflammatory pseudotumor is a tumorous lesion characterized by the infiltration of inflammatory cells and the growth of myofibroblasts. This tumor occurs most frequently in the lung, and the greatest number of intracardiac cases have been reported in small children. There are few reports of inflammatory pseudotumors occurring in adults, and only 4 cases originating in the mitral valve has so far been reported, which means that such tumors are extremely rare. For this reason, we reported the findings of this case, while adding a bibliographical survey.
		                        		
		                        		
		                        		
		                        	
5.Brief Report on the Association of Lifestyle Habits with the Pathological Condition of ki
Kengo HAMADA ; Akira NISHIKAWA ; Nobushiro NISHIMURA ; Shinichi FUJIMOTO
Kampo Medicine 2015;66(3):256-258
		                        		
		                        			
		                        			We investigated 58 general medicine outpatients with a questionnaire on sex, BMI, lifestyle habits and the pathological condition of ki. We classified sex, BMI and sleep, diet and exercise as lifestyle habit factors, and classified ki deficiency, ki obstructive depression, ki counter flow as the pathological signs of ki. After we established a disease group and a control group, we calculated ratios for the factors in each group. As a result, there were associations between hours of sleep, and recovery from fatigue with sleep, to ki deficiency. There were also associations between recovery from fatigue with sleep, and sex, to ki obstructive depression and ki counter flow.
		                        		
		                        		
		                        		
		                        	
6.Characteristics of Sagittal Spino-Pelvic Alignment in Japanese Young Adults.
Kenji ENDO ; Hidekazu SUZUKI ; Hirosuke NISHIMURA ; Hidetoshi TANAKA ; Takaaki SHISHIDO ; Kengo YAMAMOTO
Asian Spine Journal 2014;8(5):599-604
		                        		
		                        			
		                        			STUDY DESIGN: Radiological analysis of normal patterns of sagittal alignment of the spine. PURPOSE: This study aimed to clarify the characteristics of normal sagittal spino-pelvic alignment in Asian people. OVERVIEW OF LITERATURE: It is known that there are differences in these parameters based on age, gender, and race. In order to properly plan for surgical correction of the spine for Asian patients, it is necessary to understand the normal spino-pelvic alignment parameters for this population. METHODS: This study analyzed 86 Japanese healthy young adult volunteers (48 men and 38 women; age 35.9+/-11.1 (mean+/-standard deviation [SD]). The following parameters were measured on lateral standing radiographs of the entire spine: sagittal vertical axis (SVA), horizontal distance between the C7 plumb line and the posterior superior corner of the superior margin of S1, thoracic kyphotic angle (TK), lumbar lordotic angle (LLA), sacral slope (SS), pelvic tilt (PT), and pelvic incidence (PI). RESULTS: The values (mean+/-SD) of SVA, TK, LLA, SS, PT, and PI were 8.45+/-25.7 mm, 27.5+/-9.6degrees, 43.4+/-14.6degrees, 34.6+/-7.8degrees, 13.2+/-8.2degrees, and 46.7+/-8.9degrees, respectively. The Japanese young adults evaluated in this study tended to have a smaller PI, LLA, TK, and SVA than most Caucasian people. Regarding gender differences, SVA was significantly longer and TK was significantly smaller in men; however, there was no statistically significant difference in LLA, SS, PA, and PI. CONCLUSIONS: Japanese young adults apparently have smaller PI and LLA values than Caucasian people. When making decisions for optimal sagittal spinal alignment, racial differences should be considered.
		                        		
		                        		
		                        		
		                        			Asian Continental Ancestry Group*
		                        			;
		                        		
		                        			Axis, Cervical Vertebra
		                        			;
		                        		
		                        			Continental Population Groups
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Spine
		                        			;
		                        		
		                        			Volunteers
		                        			;
		                        		
		                        			Young Adult*
		                        			
		                        		
		                        	
7.Kinematic Analysis of the Cervical Cord and Cervical Canal by Dynamic Neck Motion.
Kenji ENDO ; Hidekazu SUZUKI ; Hirosuke NISHIMURA ; Hidetoshi TANAKA ; Takaaki SHISHIDO ; Kengo YAMAMOTO
Asian Spine Journal 2014;8(6):747-752
		                        		
		                        			
		                        			STUDY DESIGN: Normal cervical sagittal length patterns were measured by magnetic resonance imaging (MRI). PURPOSE: The aim of this study was to evaluate the relationship of sagittal length patterns between the cervical cord and the cervical canal in flexion-extension kinematics. OVERVIEW OF LITERATURE: Cervical dynamic factors sometimes cause a cervical spondylotic myelopathy in elderly subjects and an overstretching myelopathy in juvenile subjects. Previous studies showed the length changing of the cervical cord in flexion and extension. However, there is no detailed literature about the relationship between cervical vertebral motion and cord distortion yet. METHODS: Sixty-two normal subjects (28 male and 34 female, 42.1+/-8.5 years old) without neck motion disturbances and abnormalities on cervical X-ray and MRI were enrolled in this study. RESULTS: The cervical cord length was significantly longer in flexion and significantly shorter in extension in all cervical cord sagittal lines. The cervical canal length pattern was also the same as the cervical cord. The elongation of the cervical cord and canal was the largest at the site of the posterior cervical canal and the shortest at the anterior canal site. The positions of the cerebellar tonsils were verified at each neck position. CONCLUSIONS: The posterior elements of the cervical canal were most affected by neck motion. Movement directions of the upper cervical cord were verified among the various neck positions.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Biomechanical Phenomena
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Neck*
		                        			;
		                        		
		                        			Palatine Tonsil
		                        			;
		                        		
		                        			Spinal Cord Diseases
		                        			
		                        		
		                        	
8.A Case of Late Acute Type A Aortic Dissection after Coronary Artery Bypass Grafting
Kengo Nishimura ; Shigeto Miyasaka ; Keisuke Morimoto ; Iwao Taniguchi
Japanese Journal of Cardiovascular Surgery 2010;39(5):273-275
		                        		
		                        			
		                        			Late acute type A aortic dissection after coronary artery bypass grafting (CABG) is rare, and only a few cases have been published in the literature. It is important to treat cases of living graft during reoperation. We report a successful surgical treatment in a case of late acute type A aortic dissection after CABG. A 68-year-old man underwent a triple CABG (to the left anterior descending artery with left internal thoracic artery, to the left circumflex artery with left radial artery, and to the right coronary artery with right gastroepiploic artery) beating heart procedure using a centrifugal pump and pulmonary assist with closed circuit due to unstable angina pectoris in December 2007 and had presented with sudden anterior chest pain, and was found to have an ascending aortic dissection (type A) on enhanced computed tomography in May, 2009. We performed ascending artery replacement, paying special attention to the living graft performed through a median sternotomy. The postoperative course was uneventful and he was discharged on the 22nd postoperative day.
		                        		
		                        		
		                        		
		                        	
9.Enhancement of Sternal Stability with Poly-L-lactide Costal Coaptation Pins for Patients Undergoing Coronary Artery Bypass Grafting Using the Internal Thoracic Artery
Munehiro Saiki ; Yoshinobu Nakamura ; Akira Marumoto ; Shingo Harada ; Naotaka Uchida ; Kengo Nishimura ; Yasushi Kanaoka ; Motonobu Nishimura
Japanese Journal of Cardiovascular Surgery 2009;38(2):96-99
		                        		
		                        			
		                        			We evaluated the efficacy of sternal coaptation pins used to improve the fixation of the transected sternum after coronary artery bypass grafting (CABG) with the internal thoracic artery (ITA). The subjects were 37 patients who underwent scheduled single CABG with ITA in our department and they were classified into two groups, i. e., Group A, without sternal pins (18 patients), and Group B, with sternal pins (19 patients). The efficacy was assessed by the following measurements : drain bleeding volume up to 12 and 24 h after ICU admission, the time until the removal of drain, surgical site infection (SSI) and the maximum split level between the sternal body and manubrium after surgery. Drain bleeding volume up to 12 and 24 h after ICU tended to be less in Group B. The time until the removal of drain was significantly shorter in Group B. SSI was 17% in Group A but 0% in Group B. The use of sternal coaptation pins reduced misalignment of the coapted sternum, and we belive that the use of sternal coaptation pins contributed to the early removal of drain, and SSI reduction.
		                        		
		                        		
		                        		
		                        	
10.Long-Term Results after Surgery for Abdominal Aortic Aneurysm.
Masahiko Ikebuchi ; Kengo Nishimura ; Maromi Tachibana ; Teruo Maeda ; Yasushi Kanaoka ; Shigetsugu Ohgi
Japanese Journal of Cardiovascular Surgery 2002;31(2):100-104
		                        		
		                        			
		                        			We evaluated long-term survival and morbidity of 191 patients (161 non-ruptured and 30 ruptured) undergoing abdominal aortic aneurysm repair between 1980 and 1997. Thirty-day mortality rates of non-ruptured and ruptured aneurysms were 1.2% and 36.6%, respectively. Hospital death occurred in 3.1% of patients with non-ruptured aneurysms and 53.3% of those with ruptured aneurysms. Cumulative survival rates after successful AAA repair at 5 and 10 years were 76.3% and 42.3%, respectively. These were lower than survival rates in the age- and gender-matched general population. The most frequent cause of late death was cardiac problems (28.8%) including myocardial infarction. Other causes included stroke (19.2%), malignant neoplasm (17.3%), and ruptured recurrent aneurysms at or above the proximal anastomosis (9.6%) including aorto-enteric fistulas. Regarding late vascular complications, recurrent aneurysms at or above the proximal anastomosis were found in 10% of patients, including 3.5% of true aneurysms, 4.7% of anastomotic aneurysms, and 1.8% of aorto-enteric fistulas. Thoracic aortic aneurysms were found in 3.7% and aortic dissection in 4.2%. Cumulative graft patency rates at 10 and 15 years were 97.4% and 90.9%, respectively. Suppressive treatment for arteriosclerosis and continuous careful follow-up with an aggressive diagnostic approach may reduce morbidity and mortality from recurrent aneurysms or coronary artery disease, thereby improving late survival after AAA surgery.
		                        		
		                        		
		                        		
		                        	
            

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