1.Dome-shaped pituitary enlargement in primary hypothyroidism
Satyam Chakraborty ; Kajari Bhattacharya ; Kalyan Kumar Gangopadhyay ; Mona Tiwari ; Rajan Palui
Journal of the ASEAN Federation of Endocrine Societies 2020;35(2):238-243
		                        		
		                        			
		                        			We describe three cases of primary hypothyroidism which presented initially to neurosurgery department with pituitary hyperplasia.  We  have  found  a  novel  pattern  of  ‘dome-shaped’  enlargement  of  pituitary  in  MRI  of  these  patients.  Out  of  these  3  patients,  in  two  of  them,  the  planned  surgery  was  deferred  when  endocrinologists  were  consulted  and  the  pituitary hyperplasia completely resolved with levothyroxine treatment. In the third case, pituitary surgery was already performed before endocrinology consultation and histopathology revealed thyrotroph hyperplasia. The  hyperplastic  lesions  described  typically  have  a  homogenous  symmetrical  ‘dome’  shaped  architecture  unlike  the  non-functioning pituitary adenoma (NFPA), which usually might often be of varying shapes and homogeneity. Analysis of  pituitary  images  from  similar  case  reports  published  in  literature,  also  showed  this  typical  ‘dome’  shaped  pituitary  enlargement. This imaging characteristic can be a clue to look for underlying hormone deficiency, especially in primary hypothyroidism. Therefore, a thorough endocrine evaluation especially looking for primary hypothyroidism in such dome-shaped  pituitary  lesions  are  mandatory  to  prevent  unwarranted  neuro-surgical  intervention  as  treatment  of  primary  hypothyroidism may result in resolution of the abnormal enlargement.
		                        		
		                        		
		                        		
		                        			Pituitary Neoplasms
		                        			;
		                        		
		                        			  Adenoma
		                        			;
		                        		
		                        			 Hyperplasia
		                        			;
		                        		
		                        			  Pituitary Diseases
		                        			
		                        		
		                        	
2.Identification of Ganglion cyst causing suprascapular nerve neuropathy by high resolution neurosonography
Seena Vengalil ; Veeramani Preethish-Kumar ; Kiran Polavarapu ; Kajari Bhattacharya Atchayaram Nalini
Neurology Asia 2016;21(4):381-383
		                        		
		                        			
		                        			Suprascapular neuropathy is a rare cause of non-specific shoulder pain affecting all age groups.
Magnetic resonance imaging is the most common modality utilized to investigate the cause of
suprascapular neuropathy. We report here a case of 22 year old man who presented with diffuse right
shoulder region pain and severe wasting of the right infraspinatus muscle of 2 months duration. He
was engaged in regular overhead activities at a gymnasium for about 2 years. A possible diagnosis
of suprascapular nerve entrapment was considered. The patient was investigated with high resolution
neurosonography, which showed a ganglion (paralabral) cyst at the spinoglenoid notch compressing
the suprascapular nerve. We propose the use of neurosonography as an economical and effective
tool for initial screening of non-specific shoulder pain with or without wasting/weakness of scapular
muscles. An early identification of the cause of the neuropathy prior to the onset of muscle weakness/
wasting, and therapeutic intervention is able to avoid permanent disability
		                        		
		                        		
		                        		
		                        			Shoulder Pain
		                        			
		                        		
		                        	
            

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