1.Long-term structural and functional nasomaxillary evolution of children with mouth-breathing after rapid maxillary expansion: An 8-year follow-up study
Raquel Harumi Uejima SATTO ; Emerson Taro Inoue SAKUMA ; José Dirceu RIBEIRO ; Eulalia SAKANO
The Korean Journal of Orthodontics 2025;55(2):95-104
Objective:
To evaluate the effects of rapid maxillary expansion (RME) on nasal patency and nasomaxillary dimensions in children and adolescents with mouthbreathing through 8 years of clinical follow-up.
Methods:
RME was performed using a Hyrax orthodontic appliance in 28 mouth-breathers (6–13 years old).During follow-up, objective tests of nasal respiratory function were conducted, such as acoustic rhinometry, which provided the minimum cross-sectional areas of the nasal cavity, and active anterior computed rhinomanometry, which measured inspiratory nasal resistance. The tomographic widths of the coronal sections of the nose and maxilla were also measured. Fisher’s exact test and the Mann–Whitney U test were used to compare categorical and numerical variables, respectively, in mouth-breathers with and without allergic rhinitis.Temporal evolution was assessed using generalized estimating equation models.Statistical significance was set at P < 0.05.
Results:
There was a reduction in inspiratory resistance after RME with a stable improvement in nasal patency during the 8-year follow-up period (P = 0.0179). All nasal and maxillary tomographic widths showed statistically significant increases in the short-term (P < 0.0001), and most of them showed significant increases in the long-term when compared with the pre-expansion period. Tomographic measurements were not influenced by allergic rhinitis.
Conclusions
Our study showed that RME promoted and maintained the widening of the posterior maxillary structure in children and adolescents with mouth-breathing, with a decrease in inspiratory nasal resistance during the 8-year follow-up period. These findings highlight the importance of RME in mouth-breathers with maxillary atresia.
2.Effect of bisphosphonate vs. osteoprotegerin during orthodontic tooth movement: A systematic review and meta-analysis
Kuri Tupak SARANGOQUISHPE ; María Isabel CABRERAPADRÓN ; José Esteban TORRACCHICARRASCO ; Gloria ANDRADE-MEDINA ; Cesar Heriberto JUELAMOSCOSO
The Korean Journal of Orthodontics 2025;55(2):120-130
Objective:
Orthodontic appliances are commonly used to achieve anchorage during orthodontic treatments; however, their use can contribute to oral diseases. Studies have shown that bisphosphonates and osteoprotegerin are highly effective in reducing orthodontic tooth movement. To determine the efficacy of bisphosphonates and osteoprotegerin in reducing orthodontic tooth movement.
Methods:
A comprehensive search was conducted across five databases—MEDLINE-PubMed, Scopus, Google Scholar, ScienceDirect, and Taylor & Francis—up to August 2, 2023. Clinical trials conducted in healthy animals, where bisphosphonates and osteoprotegerin were administered during tooth movement, were included. The search identified 3,099 articles, which underwent a two-phase screening process, resulting in twelve studies for the systematic review and seven for the meta-analysis. Risk of bias was assessed using the SYRCLE tool, and Egger’s regression was used to evaluate publication bias.
Results:
The administration of bisphosphonates was more effective than osteoprotegerin in reducing mesiodistal orthodontic movement. However, osteoprotegerin did not significantly reduce orthodontic tooth movement.
Conclusions
The findings align with previous studies, confirming the superior efficacy of bisphosphonates over osteoprotegerin. Further research is required to determine the optimal dosage and mechanism of action for these drugs in clinical practice, considering the specific objectives of orthodontic treatments.
4.Long-term structural and functional nasomaxillary evolution of children with mouth-breathing after rapid maxillary expansion: An 8-year follow-up study
Raquel Harumi Uejima SATTO ; Emerson Taro Inoue SAKUMA ; José Dirceu RIBEIRO ; Eulalia SAKANO
The Korean Journal of Orthodontics 2025;55(2):95-104
Objective:
To evaluate the effects of rapid maxillary expansion (RME) on nasal patency and nasomaxillary dimensions in children and adolescents with mouthbreathing through 8 years of clinical follow-up.
Methods:
RME was performed using a Hyrax orthodontic appliance in 28 mouth-breathers (6–13 years old).During follow-up, objective tests of nasal respiratory function were conducted, such as acoustic rhinometry, which provided the minimum cross-sectional areas of the nasal cavity, and active anterior computed rhinomanometry, which measured inspiratory nasal resistance. The tomographic widths of the coronal sections of the nose and maxilla were also measured. Fisher’s exact test and the Mann–Whitney U test were used to compare categorical and numerical variables, respectively, in mouth-breathers with and without allergic rhinitis.Temporal evolution was assessed using generalized estimating equation models.Statistical significance was set at P < 0.05.
Results:
There was a reduction in inspiratory resistance after RME with a stable improvement in nasal patency during the 8-year follow-up period (P = 0.0179). All nasal and maxillary tomographic widths showed statistically significant increases in the short-term (P < 0.0001), and most of them showed significant increases in the long-term when compared with the pre-expansion period. Tomographic measurements were not influenced by allergic rhinitis.
Conclusions
Our study showed that RME promoted and maintained the widening of the posterior maxillary structure in children and adolescents with mouth-breathing, with a decrease in inspiratory nasal resistance during the 8-year follow-up period. These findings highlight the importance of RME in mouth-breathers with maxillary atresia.
5.Effect of bisphosphonate vs. osteoprotegerin during orthodontic tooth movement: A systematic review and meta-analysis
Kuri Tupak SARANGOQUISHPE ; María Isabel CABRERAPADRÓN ; José Esteban TORRACCHICARRASCO ; Gloria ANDRADE-MEDINA ; Cesar Heriberto JUELAMOSCOSO
The Korean Journal of Orthodontics 2025;55(2):120-130
Objective:
Orthodontic appliances are commonly used to achieve anchorage during orthodontic treatments; however, their use can contribute to oral diseases. Studies have shown that bisphosphonates and osteoprotegerin are highly effective in reducing orthodontic tooth movement. To determine the efficacy of bisphosphonates and osteoprotegerin in reducing orthodontic tooth movement.
Methods:
A comprehensive search was conducted across five databases—MEDLINE-PubMed, Scopus, Google Scholar, ScienceDirect, and Taylor & Francis—up to August 2, 2023. Clinical trials conducted in healthy animals, where bisphosphonates and osteoprotegerin were administered during tooth movement, were included. The search identified 3,099 articles, which underwent a two-phase screening process, resulting in twelve studies for the systematic review and seven for the meta-analysis. Risk of bias was assessed using the SYRCLE tool, and Egger’s regression was used to evaluate publication bias.
Results:
The administration of bisphosphonates was more effective than osteoprotegerin in reducing mesiodistal orthodontic movement. However, osteoprotegerin did not significantly reduce orthodontic tooth movement.
Conclusions
The findings align with previous studies, confirming the superior efficacy of bisphosphonates over osteoprotegerin. Further research is required to determine the optimal dosage and mechanism of action for these drugs in clinical practice, considering the specific objectives of orthodontic treatments.
7.Infected Paravisceral Aneurysm Repair with Parallel Stent Grafts
Iria Fernández ÁLVAREZ ; Javier Fernández LORENZO ; Jorge Vidal REY ; José Manuel Encisa de SÁ
Vascular Specialist International 2025;41(1):1-
An infected aortic aneurysm (IAA) is a rare but potentially life-threatening pathology characterized by rapid growth and a substantial risk of rupture compared to non-infected aneurysms. Reports on the endovscular treatment of infected paravisceral aneurysms are limited in the literature. This article describes our experience with endovascular repair of IAAs involving the visceral arteries and includes a literature review. We present two cases of symptomatic IAAs located at the celiac trunk ostium in high-risk surgical patients. Both cases were successfully treated with the parallel stent grafting (PG) technique in combination with prolonged antibiotic therapy. A bibliographic review of the endovascular treatment of IAAs was also conducted. Complex endovascular repair of paravisceral IAAs using a combination of a thoracic aortic stent graft and PG, together with prolonged antibiotic therapy, appears to be a reasonable treatment option with promising short- and medium-term results.
8.Association Between Functional Dyspepsia and Binge Eating Disorder: A Frequent, Often Overlooked Overlap Clinical Presentation
Francisco A FÉLIX-TÉLLEZ ; Alejandra X CRUZ-SALGADO ; José M REMES-TROCHE ; Ángel R FLORES-RENDON ; Héctor R ORDAZ-ÁLVAREZ ; José A VELARDE-RUIZ VELASCO ; Marco A O FLORES-LIZÁRRAGA ; José I SOTO-GONZÁLEZ ; Nadia S ABIZAID-HERRERA
Journal of Neurogastroenterology and Motility 2025;31(1):95-101
Background/Aims:
This study aims to investigate the association between Binge Eating Disorder and functional dyspepsia in a Mexican population, focusing on symptomatology and demographic characteristics.
Methods:
We conducted a cross-sectional study on 1016 subjects, evaluating binge eating disorder (BED) and functional dyspepsia based on the Rome IV criteria. Data collection included sociodemographic information, gastrointestinal symptom severity, and anxiety/depression screening using validated tools. A multivariate logistic regression analysis with the 2 test was conducted for comparison analysis.
Results:
The prevalence of dyspepsia in BED was 53.6% (95% CI, 46-56). Postprandial fullness (OR, 1.52; 95% CI, 1.06-2.17; P = 0.021) and overlap syndrome (OR, 1.80; 95% CI, 1.25-2.60; P = 0.002) were significantly associated with BED. Patients with BED also presented more severe postprandial distress syndrome (P = 0.027). Anxiety was prevalent in BED patients, while depression was more prominent in patients with BED and dyspepsia overlap.
Conclusions
BED patients have a high prevalence of dyspepsia with an association between postprandial fullness and this eating disorder. BED appears to be more prevalent in younger individuals and males. These findings underscore the importance of considering dyspepsia in the management of BED and highlight the need for further research on this association.
9.Associations of Sex and Household Area With Physical Activity and Sedentary Behavior During Total and Partial COVID-19 Lockdowns in Chile: A Study in Adults Aged 18-44 Years
Jairo VANEGAS-LÓPEZ ; Rodrigo GUZMÁN-VENEGAS ; Gabriel MARZUCA-NASSR ; Claudio MUÑOZ-POBLETE ; Gonzalo QUIROZ-SANDOVAL ; Juan SILVA-URRA ; Andres ORELLANA-URIBE ; Sebastián DUBÓ ; Ignacio SEPÚLVEDA ; José Luis MÁRQUEZ
Journal of Preventive Medicine and Public Health 2025;58(2):177-187
Objectives:
The coronavirus disease 2019 pandemic led to various intensities of lockdowns, affecting lifestyles globally. This study investigates the impact of partial lockdown versus total lockdown on adult physical activity (PA) and sedentary behavior.
Methods:
A cross-sectional online survey was conducted from April 2020 to October 2020, with 493 participants included in the analysis.
Results:
The analysis revealed no significant differences in total PA or total sitting time between partial lockdown and total lockdown scenarios. However, moderate physical activity (MPA) significantly decreased during total lockdowns, with more pronounced reductions among females than males. Notably, a positive correlation was found between household area and MPA, suggesting that larger living spaces may encourage more PA. A negative correlation was observed between sitting time and MPA during both types of lockdown.
Conclusions
Total lockdown conditions were associated with a significant decrease in MPA, highlighting sex disparities in PA responses. Living space size emerged as a crucial factor in maintaining PA levels during restricted conditions. This study emphasizes the need to consider environmental and demographic factors in public health strategies during prolonged periods of restricted movement.
10.Evaluation of novel cardiovascular risk calculators in patients with rheumatoid arthritis
Dionicio Angel GALARZA-DELGADO ; Valeria GONZALEZ-GONZALEZ ; Natalia GUAJARDO-JAUREGUI ; Jesus Alberto CARDENAS-DE LA GARZA ; Rosa Icela ARVIZU-RIVERA ; Maria Fernanda ELIZONDO-BENITEZ ; Andrea Lizbeth GUAJARDO-ALDACO ; Jose Ramon AZPIRI-LOPEZ ; Iris Jazmin COLUNGA-PEDRAZA
Journal of Rheumatic Diseases 2025;32(2):145-147

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