1.Death rate and life loss caused by injuries in Jinshan District, Shanghai in 1990-2023
Xiaoyun ZHU ; Decai ZENG ; Zhenjuan LI ; Wenxia XIA
Journal of Public Health and Preventive Medicine 2025;36(5):54-58
		                        		
		                        			
		                        			Objective  To analyze the death rate and life loss of injuries in Jinshan District of Shanghai from 1990 to 2023, and to provide a scientific basis for the formulation of injury prevention and control measures.  Methods  Excel 2010 was used to establish a database for injury death reports in Jinshan District from 1990 to 2023, and the crude mortality rate, standardized mortality rate, age-specific mortality rate, potential years of life lost (PYLL), rate of potential years of life lost (PYLLR) and standardized rate of potential years of life lost (SPYLLR) were calculated.  Results  From 1990 to 2023, the crude mortality rate due to injuries in Jinshan District was 52.25/100 000, while the standardized mortality rate was 36.95/100 000. Based on the standardized mortality rate, the top four causes of injury-related deaths were traffic accidents, falls, drowning, and suicide. Traffic accidents ranked first as the leading cause of death for both males (19.30/100 000) and females (8.41/100 000). The top cause of death for the 0-14 years old group was drowning, the 15-64 years old group was traffic accidents, and the 65 years old and above was falls. Over the 34-year period, according to SPYLLR, the top four causes of death for both genders were consistently traffic accidents, drowning, suicide, and falls. Conclusion  From 1990 to 2023, traffic accidents, falls, drowning, and suicide have been the primary causes of injury-related deaths in Jinshan District, Shanghai. It is essential to develop targeted prevention and control strategies based on the specific characteristics of these injury-related fatalities.
		                        		
		                        		
		                        		
		                        	
2.Death rate and life loss caused by injuries in Jinshan District, Shanghai in 1990-2023
Xiaoyun ZHU ; Decai ZENG ; Zhenjuan LI ; Wenxia XIA
Journal of Public Health and Preventive Medicine 2025;36(5):54-58
		                        		
		                        			
		                        			Objective  To analyze the death rate and life loss of injuries in Jinshan District of Shanghai from 1990 to 2023, and to provide a scientific basis for the formulation of injury prevention and control measures.  Methods  Excel 2010 was used to establish a database for injury death reports in Jinshan District from 1990 to 2023, and the crude mortality rate, standardized mortality rate, age-specific mortality rate, potential years of life lost (PYLL), rate of potential years of life lost (PYLLR) and standardized rate of potential years of life lost (SPYLLR) were calculated.  Results  From 1990 to 2023, the crude mortality rate due to injuries in Jinshan District was 52.25/100 000, while the standardized mortality rate was 36.95/100 000. Based on the standardized mortality rate, the top four causes of injury-related deaths were traffic accidents, falls, drowning, and suicide. Traffic accidents ranked first as the leading cause of death for both males (19.30/100 000) and females (8.41/100 000). The top cause of death for the 0-14 years old group was drowning, the 15-64 years old group was traffic accidents, and the 65 years old and above was falls. Over the 34-year period, according to SPYLLR, the top four causes of death for both genders were consistently traffic accidents, drowning, suicide, and falls. Conclusion  From 1990 to 2023, traffic accidents, falls, drowning, and suicide have been the primary causes of injury-related deaths in Jinshan District, Shanghai. It is essential to develop targeted prevention and control strategies based on the specific characteristics of these injury-related fatalities.
		                        		
		                        		
		                        		
		                        	
3.Trend analysis of the death level and probability of premature death caused by chronic obstructive pulmonary disease in Jinshan District, Shanghai, 1980-2020
Xiaoyun ZHU ; Xia GAO ; Xihong TANG ; Biping MA ; Qi SHU
Journal of Public Health and Preventive Medicine 2022;33(3):47-51
		                        		
		                        			
		                        			Objective  To analyze the trend of death level and the probability of premature death caused by chronic obstructive pulmonary disease (COPD) in Jinshan District of Shanghai from 1980 to 2020, and to provide reference for the formulation of prevention and control measures of COPD.  Methods  The death cases of COPD in Jinshan District from 1980 to 2020 were collected through the death cause registration information system. The crude mortality, standardized mortality, age group mortality, early death probability and annual change percentage in different periods were calculated.  Results  From 1980 to 2020, the crude mortality of COPD in Jinshan District was 154.38/100 000, and the standardized mortality was 82.66/100,000. In the past 41 years, the standardized mortality of COPD showed a downward trend in males and females (APC=-1.79%, -2.52%, P<0.001). In the same period, the mortality of COPD in subjects aged 30-69 years old and subjects aged 70 years old and above also decreased (APC=-8.79%, -4.79%, P<0.001), and the probability of premature death caused by COPD showed a downward trend in males and females (APC=-9.61%, -10.71%, P<0.001).  Conclusion  The mortality rate and the probability of premature death of COPD in Jinshan District have decreased in the past 41 years. However, COPD is still one of the major chronic diseases that pose a serious threat to the health of residents in Jinshan District. Comprehensive prevention and treatment measures should be taken to reduce the mortality and the probability of premature death of COPD.
		                        		
		                        		
		                        		
		                        	
4.Attenuation of anti-measles antibody in the healthy population aged 1-14 years old in an urban district, Shanghai
Shu-hua LI ; Cheng-xiao WANG ; Xi-hong TANG ; Xia GAO ; Chun-zhu WU ; Fan-di XIE ; Yu CHEN
Shanghai Journal of Preventive Medicine 2021;33(5):410-413
		                        		
		                        			
		                        			Objective:To determine the level of anti-measles antibody in healthy population aged 1-14 years old in Shanghai, and project the risk of measles incidence in adult population in the future, which may provide evidence for enhancing the measles immunization strategy. Methods:A cross-sectional study was conducted to collect the serum of healthy people aged 1-14 years old in an urban district hospital in Shanghai. Serum concentration of anti-measles IgG antibody was examined by enzyme-linked immunosorbent assay (ELISA) and dynamics of IgG antibody was compared. Results:The prevalence of anti-measles antibody in healthy people aged 1-14 years old was determined to be 95.29%, and the antibody protection rate was 61.86%. There was no significant difference in the distribution of antibody between men and women (
		                        		
		                        	
		                				5.Semi-quantitative risk assessment of the contamination of Vibrio parahaemolyticus  in oysters from Jinshan District, Shanghai
		                			
		                			Chen-chen LI ; Dong-fang HAN ; Feng-xia QUE ; Hong-yan WU ; Dan-dan YU ; Yu-long YE
Shanghai Journal of Preventive Medicine 2021;33(3):232-
		                        		
		                        			
		                        			Objective To investigate the prevalence of 
		                        		
		                        	
6.Characterization of Vibrio parahaemolyticus isolated from diarrhea patients in Jinshan District,Shanghai
Bo-wen YANG ; Yu-long YE ; Jia-chun YUAN ; Feng-xia QUE ; Hong-you CHEN
Shanghai Journal of Preventive Medicine 2021;33(8):714-719
		                        		
		                        			
		                        			Objective:To determine the distribution and epidemic characteristics of 
		                        		
		                        	
7.Bioremediation of Hexavalent Chromium Pollution by Sporosarcina saromensis M52 Isolated from Offshore Sediments in Xiamen, China.
Ran ZHAO ; Bi WANG ; Qing Tao CAI ; Xiao Xia LI ; Min LIU ; Dong HU ; Dong Bei GUO ; Juan WANG ; Chun FAN ;
Biomedical and Environmental Sciences 2016;29(2):127-136
OBJECTIVECr(VI) removal from industrial effluents and sediments has attracted the attention of environmental researchers. In the present study, we aimed to isolate bacteria for Cr(VI) bioremediation from sediment samples and to optimize parameters of biodegradation.
METHODSStrains with the ability to tolerate Cr(VI) were obtained by serial dilution and spread plate methods and characterized by morphology, 16S rDNA identification, and phylogenetic analysis. Cr(VI) was determined using the 1,5-diphenylcarbazide method, and the optimum pH and temperature for degradation were studied using a multiple-factor mixed experimental design. Statistical analysis methods were used to analyze the results.
RESULTSFifty-five strains were obtained, and one strain (Sporosarcina saromensis M52; patent application number: 201410819443.3) having the ability to tolerate 500 mg Cr(VI)/L was selected to optimize the degradation conditions. M52 was found be able to efficiently remove 50-200 mg Cr(VI)/L in 24 h, achieving the highest removal efficiency at pH 7.0-8.5 and 35 °C. Moreover, M52 could completely degrade 100 mg Cr(VI)/L at pH 8.0 and 35 °C in 24 h. The mechanism involved in the reduction of Cr(VI) was considered to be bioreduction rather than absorption.
CONCLUSIONThe strong degradation ability of S. saromensis M52 and its advantageous functional characteristics support the potential use of this organism for bioremediation of heavy metal pollution.
Biodegradation, Environmental ; China ; Chromium ; metabolism ; Geologic Sediments ; microbiology ; RNA, Ribosomal, 16S ; genetics ; Sporosarcina ; genetics ; isolation & purification ; metabolism
8.Early primary pulmonary mucosa-associated lymphoid tissue lymphoma:a prognostic analysis and literature review
Ge WEN ; Yujing ZHANG ; Jinshan ZHANG ; Shaoqing NIU ; Yiyang LI ; Lingling FENG ; Yunfei XIA
Chinese Journal of Radiation Oncology 2016;25(7):713-717
		                        		
		                        			
		                        			Objective To analyze the clinical features,treatment methods,and prognostic factors for early primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma.Methods A retrospective analysis was performed on the clinical data,treatment outcomes,and survival of 32 patients with early pulmonary MALT lymphoma from March 2001 to September 2013.The median age of those patients was 56 years.Twenty-three patients had stage ⅠE disease and nine had stage Ⅱ E disease.According to the marginal zone B-cell lymphoma prognostic index (MZLPI),twenty-three patients were scored as 0 and nine as 1.Nine patients received radiotherapy,eight patients underwent surgery alone,three patients underwent surgery plus chemotherapy,and twelve patients received chemotherapy alone.The Kaplan-Meier method was adapted for calculating the OS,PFS and the log-rank test was used for survival difference analysis and univariate prognostic analysis.Results The 5-year sample size was 22.The 5-year overall survival (OS) and progression-free survival (PFS) rates were 84.5% and 73.2%,respectively.Radiotherapy yielded an overall response rate of 100%,including a complete response rate of 66.7% and a partial response rate of 33.3%.The univariate analysis showed that non-radiotherapy treatment was a prognostic factor for poor PFS.The patients treated with radiotherapy had significantly higher 5-year PFS rates than those treated without radiotherapy (100% vs.63.0%,P=0.029),while there was no significant difference in 5-year OS rate between these two groups (100% vs.78.8%,P=0.129).Age older than 60 years,an ECOG score of 2,and an MZLPI score of 1 were prognostic factors for poor PFS (P=0.041,0.018,and 0.044) and OS (P=0.001,0.001,and 0.003).Conclusions The prognostic factors for early pulmonary MALT lymphoma include age,ECOG score,and MZLPI score.Low-dose involved-field radiotherapy (24-30 Gy) can improve local control and survival.
		                        		
		                        		
		                        		
		                        	
9.Molecular epidemiology study on an acute gastroenteritis outbreak caused by a new GII. 4 norovirus recombinant strain.
Can-lei SONG ; Jia-chun YUAN ; Zhi-cheng CAO ; Lan LI ; Hai-ming ZHONG ; Jian-ming ZHU ; Xia GAO
Chinese Journal of Preventive Medicine 2013;47(12):1114-1117
OBJECTIVETo analyze the epidemiological characteristics of an acute gastroenteritis outbreak in a nursing home caused by norovirus (NoV) and the genotype of the pathogen.
METHODSOn January 29th 2013, a total of 26 acute gastroenteritis patients infected by norovirus were reported in the nursing home of Jinshan, Shanghai. A questionnaire was used to acquire information of patients involved in the outbreak, 9 stool or anal swab samples were collected from 9 patients without treatment by simple random sampling method, and 4 environmental samples from the surface of doorknobs or toilets were collected. The samples were detected by Real-time PCR for NoV, and positive samples were then amplified by routine RT-PCR. The PCR products were purified, sequenced, and aligned by comparing sequences in GenBank. Phylogenetic trees were constructed by using Clustal X, employing MEGA 5.1 program package.
RESULTSFor the 26 patients, 7 were men and 19 were women.8 samples were found NoV positive among the 13 samples when detected by real-time PCR. The sequence alignment showed that the nucleotide sequence homology between Jinshan08 and Jinshan12 strain which obtained sequencing signal was 100%. The phylogenetic analysis revealed that Jinshan08, Jinshan12 and GII.e/NV2634/BCN/Spain/2008 strains in the RdRp region were on the the same branch of evolutionary tree, the confidence level was 99%, and in the N/S region of the Capsid, 2 other strains and Lordsdal strain were in the same branch, the confidence level was 97%.
CONCLUSIONIt was confirmed that the acute gastroenteritis outbreak was caused by the new GII.4 NoV recombinant.
Aged ; Aged, 80 and over ; China ; epidemiology ; Disease Outbreaks ; Female ; Gastroenteritis ; epidemiology ; genetics ; virology ; Genetic Variation ; Humans ; Male ; Middle Aged ; Molecular Epidemiology ; Norovirus ; classification ; genetics ; isolation & purification ; Phylogeny
10.Comparison of effectiveness of intensity-modulated radiotherapy with conventional two-dimensional radiotherapy for patients with locally recurrent nasopharyngeal carcinoma
Wenjuan MA ; Jinshan ZHANG ; Kajia CAO ; Weixiong XIA
Chinese Journal of Radiation Oncology 2012;21(4):298-301
		                        		
		                        			
		                        			ObjectiveTo compare the efficacy and side-effects in locally recurrent nasopharyngeal carcinoma (NPC) treated by intensity-modulated radiotherapy (IMRT) and two-dimensional conventional radiotherapy (2DCRT).MethodsAmong the 292 newly diagnosed,nonmetastatic recurrent NPC,211were treated with IMRT and 81 with 2DCRT.All patients were staged according to the seventh edition of the UICC 2009 staging system.Kaplan-Meier and Logrank methods were used for survival analysis.A Cox proportional hazard model was used to examine prognostic factors.ResultsThe follow-up rate was 91.8%,there are 38 patients in 2DCRT and 106 patients in IMRT group was followed more than 3 years.There were significant differences in the 3-year actuarial overall survival (OS) rate ( 36.9% and 51.3%,x2 =8.44,P =0.004) and local progression-free survival (LRFS) rate (63.3% and 86.0%,x2 =13.83,P =0.000),and no significant differences in actuarial distant metastasis free survival rates (79.0% and 83.5%,x2 =0.25,P=0.618 ) between the 2DCRT group and the IMRT group.Multivariate analysis showed that T category and IMRT ( yes vs.no) were the independently prognostic factors for OS and LRFS ( x2 =9.51,5.20,P =0.002,0.023 and x2 =4.84,9.24,P =0.027,0.002 ).The incidence of grade 3and4 trismus and radiation-induced encephalopathy were 19.9%,8.1% for the IMRT group and 43.2%,24.7% for the 2DCRT group ( x2 =16.37,P =0.000 and x2 =14.64,P =0.000).Whereas,severe mucosa necrosis and/or massive hemorrhage in the nasopharynx was observed in IMRT group which was not common in 2DCRT (33.2%∶7.4%,x2 =20.19,P=0.000).ConclusionsHigher local tumor control and overall survival were achieved by IMRT than 2DCRT,the incidence of severe trismus and radiation-induced encephalopathy was also reduced by IMRT,in cost of a higher incidence of mucosa necrosis and/or massive hemorrhage in the nasopharynx.
		                        		
		                        		
		                        		
		                        	
            

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