1.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
2.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
3.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
4.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
5.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
6.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
7.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
8.Comparison on Policies for Technological Achievement Transformation through Pricing and Investment in Public Hospi-tals
Juan LI ; Hongyao MA ; Xiangrong ZHANG
Chinese Health Economics 2024;43(8):11-15
		                        		
		                        			
		                        			More and more attention is being paid by all parties to the use of pricing and investment for achievement transforma-tion.It is of great significance to enhance the technological transformation ability and economic operation and management ability of public hospitals.Beijing,Shanghai,and Shenzhen have explored the introduction of local special policies to support local public hos-pitals in converting results through priced investment.However,compared with the mature support policies of relevant national regula-tory departments for universities,the improvement are still needed.It compared the pricing and investment policies of universities and relevant local public hospitals from key aspects and contents such as decision-making power of pricing and investment,share-holding platform requirements,completion reward standards,and tax preferential policies,and analyzed the shortcomings of pricing and investment policies in public hospitals.Then it proposed some suggestions,such as exploring innovative models of achievement transformation and shareholding platforms which suitable for public hospitals,further clarifying the content of decision-making exemp-tion policies and asset loss handling procedures.It puts forward countermeasures and suggestions to better promote the transformation of scientific and technological achievements in public hospitals.
		                        		
		                        		
		                        		
		                        	
9.Efficacy and Safety of Pulse Magnetic Therapy System in Insomnia Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
Jiwu LIAO ; Sisi WANG ; Borong ZHOU ; Wei LIANG ; Ping MA ; Min LIN ; Weisen LIN ; Congrui LI ; Xiaotao ZHANG ; Hongyao LI ; Yin CUI ; Jiajia HU ; Yuanyi QIN ; Yanhua DENG ; Aibing FU ; Tianhua ZHU ; Shanlian ZHANG ; Yunhong QU ; Lu XING ; Wumei LI ; Fei FENG ; Xinping YAO ; Guimei ZHANG ; Jiyang PAN
Psychiatry Investigation 2023;20(6):559-566
		                        		
		                        			 Objective:
		                        			This study’s objective is to assess the efficacy and safety of Pulsed Magnetic Therapy System (PMTS) in improving insomnia disorder. 
		                        		
		                        			Methods:
		                        			Participants with insomnia disorder were randomly assigned to receive either PMTS or sham treatment for four weeks (n= 153; PMTS: 76, sham: 77). Primary outcomes are the Insomnia Severity Index (ISI) scores at week 0 (baseline), 1, 2, 3, 4 (treatment), and 5 (follow-up). Secondary outcomes are the Pittsburgh Sleep Quality Index at baseline and week 4, and weekly sleep diary-derived values for sleep latency, sleep efficiency, real sleep time, waking after sleep onset, and sleep duration. 
		                        		
		                        			Results:
		                        			The ISI scores of the PMTS group and the sham group were 7.13±0.50, 11.07±0.51 at week 4, respectively. There was a significant group×time interaction for ISI (F3.214, 485.271=24.25, p<0.001, ηp 2=0.138). Only the PMTS group experienced continuous improvement throughout the study; in contrast, the sham group only experienced a modest improvement after the first week of therapy. At the end of the treatment and one week after it, the response of the PMTS group were 69.7% (95% confidence interval [CI]: 58.6%–79.0%), 75.0% (95% CI: 64.1%–83.4%), respectively, which were higher than the response of the sham group (p<0.001). For each of the secondary outcomes, similar group×time interactions were discovered. The effects of the treatment persisted for at least a week. 
		                        		
		                        			Conclusion
		                        			PMTS is safe and effective in improving insomnia disorders. 
		                        		
		                        		
		                        		
		                        	
10.Study on the application of zebrafish model in the early stage of renal toxicity in drug development
Jinfeng LIANG ; Yong ZHU ; Hongyao ZHANG ; Qiaocong LAO ; Minkang MA ; Chunqi LI
Chinese Journal of Comparative Medicine 2016;26(9):30-35
		                        		
		                        			
		                        			Objective To evaluate the renal toxicity of vancomycin hydrochloride and irbesartan tablets using the zebrafish model. Methods After construction of AB zebrafish kidney model, the fish were treated with drug after fertilization 2 days (2 dpf) to 5 dpf. At the end of the experiment, the number of renal edema zebrafish was counted in each experimental group to evaluate the renal toxicity of drugs. Results The zebrafish development was normal and no obvious toxicity at the dose of 16?4 ng/fish (1/10 MNLD) for vancomycin, and zebrafish renal edema occurred rate was 3?3%, 10% and 10% respectively at the dose of 54?7 ng/fish (1/3 MNLD), 164 ng/fish (MNLD) and 273 ng/fish ( LD10 ) with the death rate of 0%, 0% and 16?7%, respectively, which indicated that there was significant renal toxicity of vancomycin at the dose of 54?7 ng/fish (1/3MNLD) to 273 ng/fish (LD10). Irbesartan didn’t induce renal toxicity at the dose of 8?3 μg/mL (1/10 MNLC) to 91 μg/mL (LC10). Conclusions The zebrafish model of renal toxicity can be used for the early evaluation of drug renal toxicity and we made evaluation of the renal toxicity of vancomycin and irbesartan with this model.
		                        		
		                        		
		                        		
		                        	
            
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