Objective  To investigate an effective method of treating primary hepatic cancer(PHC) with portal venous tumor thrombosis (PVTT).  Methods  The clinical data Of 23 patients with PHC and PVTT were retrospectivly analysed. Results  Of the 23 patieats after hepatoma resection and PVTT extraction, continuous micro  dose infusion chemotherapy or perfusion chemotherapy by DDS was adopted. In 8 patients with  main portal vein tumor thrombus, 2 died, 4 recured in 6 months. In 8 patients with the first class branch of portal vein tumor thrombus, 2 recurrd in 6 months and 6 recurred in 12 months. In 4 patients with secondary class branch of portal vein tumor thrombus, l recurred in 12 months (P