1.Traditional Chinese medicine microbiomics and its research strategies.
Guo-Zhuang ZHANG ; Shi-Lin CHEN ; Lin-Lin DONG
China Journal of Chinese Materia Medica 2023;48(3):596-607
The tight relationships between microbiome and traditional Chinese medicine(TCM)have been widely recognized. New technologies, results, and theories are emerging in the field of microbiomics in recent years with the advances in high-throughput sequencing and multi-omics technologies. Based on the previous research, the present study has proposed the concept of TCM microbiomics(TCMM), which is an interdisciplinary subject aiming at elucidating the functions and applications of microbiome in the areas of herb resources, herb processing, herb storage, and clinical effects by using modern technology of biology, ecology, and informatics. This subject essentially contains the structures, functions, interactions, molecular mechanisms, and application strategies of the microbiome associated with the quality, safety, and efficacy of TCM. Firstly, the development of the TCMM concept was summarized, with the profound understanding of TCMM on the complexity and entirety of microbiome being emphasized. Then, the research contents and applications of TCMM in promoting the sustainable development of herb resources, improving the standardization and diversification of herb fermentation, strengthening the safety of herb storage, and resolving the scientific connotation of theories and clinical efficacy of TCM are reviewed. Finally, the research strategies and methods of TCM microbiomics were elaborated from basic research, application research, and system research. TCMM is expected to promote the integrative development of TCM with frontier science and technology, thereby expanding the depth and scope of TCM study and facilitating TCM modernization.
Ecology
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Fermentation
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High-Throughput Nucleotide Sequencing
;
Medicine, Chinese Traditional
;
Research Design
2.Tsen-Hwang Shaw: Founder of Vertebrate Zoology in China.
Protein & Cell 2021;12(1):1-3
3.Ecology suitability study of Polygonatum cyrtonema.
Peng-Fei ZHANG ; Hong ZHANG ; Xiao-Bo ZHANG ; Yong-Fei YIN ; Shou-Jin LIU ; Lei LI ; Dai-Yin PENG
China Journal of Chinese Materia Medica 2020;45(13):3073-3078
Using the 260 geographical distribution records of Polygonatum cyrtonema in China, combined with 53 environmental factors, the maximum entropy modeling(MaxEnt) was used to study the ecological factors affecting the suitability distribution of P. cyrtonema. The ArcGIS software was used to predict the potential distribution of the population of P. cyrtonema. The dominant factors were chosen by using the Jackknife test and the Receiver Operating Characteristic(ROC) curve was used to evaluate the simulation. The results showed that high value of area under curve(AUC) denoted good results, which significantly differed from random predictions. Based on the evaluation criterion, the accuracies of the predictions of P. cyrtonema potential distribution in the current periods were excellent. The main environmental factors affecting the suitable growth of P. cyrtonema were the monthly precipitation, the wettest monthly precipitation, the annual average temperature range and the precipitation of November, March, February, April, May and October. There are 9 environmental factors in soil type. The potential fitness of P. cyrtonema in China is high, mainly concentra-ted in Hunan, western Hubei, Guangdong, northeastern Guangxi, southeastern Guizhou, Jiangxi, southwestern Anhui, Fujian, Zhejiang, Shaanxi, southwestern Henan and Chongqing. The growth distribution of the potential distribution area of P. cyrtonema was divided, and the zoning map of the growth suitability of P. cyrtonema was formed. Through the comparative analysis of the potential distribution range based on MaxEnt and the distribution range of literature records, the understanding of the distribution range of P. cyrtonema was expanded.
China
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Ecology
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Entropy
;
Polygonatum
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Research Design
;
Soil
4.Factors Influencing Happiness among Pregnant Women in the Ecological Systems Theory
Journal of Korean Academy of Community Health Nursing 2019;30(1):11-24
PURPOSE: This study tries to systematically understand factors that explain levels of happiness among pregnant women in the Ecological systems theory. METHODS: A descriptive, cross-sectional study was conducted with 169 pregnant women in Korea. Collected data from self-report questionnaires were analyzed by hierarchical regression analysis using the SPSS statistics 23 program. RESULTS: A total of 5 models were examined according to individual, microsystem, mesosystem, exosystem, and macrosystem in the Ecological systems theory. In the first model including individual factors, extraversion, neuroticism, and physical and psychological change constitute significant factors explaining happiness. In the second model with microsystem factors and in the third one with mesosystem factors, marital intimacy appears to be a significant factor. In the fourth model including exosystem factors, community service is a significant factor. In the final model with social atmosphere, personality (β=.15 for extraversion; β=−.30 for neuroticism), physical and psychological change (β=−.15), marital intimacy (β=.35), and community service (β= .18) turn out to be significant. These factors explain 59% of the variance of happiness in the pregnant women in Korea. CONCLUSION: Considering the fact that pregnant women's happiness is explained by microsystem and exosystem factors as well as individual factors, developing intervention programs that can promote influencing factors such as marital intimacy and community service is necessary to improve levels of happiness among pregnant women in Korea.
Atmosphere
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Community Health Services
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Cross-Sectional Studies
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Ecology
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Ecosystem
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Extraversion (Psychology)
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Family Characteristics
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Female
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Happiness
;
Humans
;
Korea
;
Pregnancy
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Pregnant Women
;
Social Welfare
5.Factors Influencing Death Anxiety in Community-Dwelling Elderly: Based on the Ecology Theory
Korean Journal of Hospice and Palliative Care 2019;22(1):30-38
PURPOSE: This study analyzed a path through which factors influencing death anxiety in the community-dwelling elderly, assuming personal organismic factors and microsystemic factors based on the ecology model purported by Belsky (1980). METHODS: This study was performed with 189 elderly people. Data were collected through a self-report questionnaire. The data were analyzed using the SPSS and AMOS programs. RESULTS: The factors influencing death anxiety in the elderly were depression, family support, social network, and familism value, and the explanatory power of these variables was 22%. Death anxiety increased with higher depression, higher familism value, larger social network, and lower family support. Spiritual well-being and elderly discrimination experience had indirect effects on death anxiety, and these effects were mediated by depression. CONCLUSION: Depression, family support, social network, and familism value were found to influence death anxiety in the elderly, and the strongest effect came from depression. To reduce death anxiety in the elderly, it is important to improve their relationship with their family and friends. Moreover, support should be provided by establishing local systems, and intervention should be provided to alleviate depression.
Aged
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Anxiety
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Depression
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Discrimination (Psychology)
;
Ecology
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Friends
;
Humans
6.Strenthening entry-exit supervision for protecting natural resources of traditional Chinese medicine.
Wen-Juan ZHU ; Xiao GUAN ; Yan-Jun CHEN ; Chun-Xin ZANG ; Gao-Hui LIU
China Journal of Chinese Materia Medica 2019;44(11):2411-2415
China is highly rich of medicinal plants. Traditional Chinese medicine(TCM) has a long history and is important traditional resources in China. As one of the important strategic resources and the link among all the countries along the ancient "Silk Road", TCM has played important role in economy, politics, society and ecology. With the initiative of the "Belt and Road" in recent years, many natural resources of TCM now are facing the risk of extinction due to more and more frequent trade between China and other countries, also the increase of export has influenced to the stock of TCM. In order to prevent the loss of the resources, strengthen the protection and sustainable use of TCM, our study provided the strategies to the natural resources of TCM's entry-exit supervision from nine aspects, like law and regulation system, based on the analysis of current supervision status quo.
China
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Conservation of Natural Resources
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Drugs, Chinese Herbal
;
Ecology
;
Medicine, Chinese Traditional
;
Plants, Medicinal
7.Sulzbacheromyces sinensis, an Unexpected Basidiolichen, was Newly Discovered from Korean Peninsula and Philippines, with a Phylogenetic Reconstruction of Genus Sulzbacheromyces
Dong LIU ; Xin YU WANG ; Li Song WANG ; Nitaro MAEKAWA ; Jae Seoun HUR
Mycobiology 2019;47(2):191-199
Most of lichens are formed by Ascomycota, less than 1% are lichenized Basidiomycota. The flora investigation of lichenized Ascomycota of South Korea has been well studied in the past three decades; however, prior to this study, none of basidiolichens was discovered. During the recent excursion, an unexpected clavarioid basidiolichen, Sulzbacheromyces sinensis was collected. Morphology and ecology has been recorded in detail. DNA was extracted, and ITS, 18S, 28S nuclear rDNA were generated. In order to further confirm the systematic position of the Korean specimens, maximum likelihood and Bayesian inference analysis including all the species of the order Lepidostromatales were conducted based on the ITS. As a result, the phylogenetic tree of the order Lepidostromatales was reconstructed, which differed from the previous studies. The inferred phylogenetic tree showed that species of Sulzbacheromyces in three different continents (Asia, South Africa and South America) were separated into three clades with support. In this study, the species worldwide distribution map of Lepidostromatales was illustrated, and S. sinensis had a widest distribution range (paleotropical extend to the Sino-Japanese) than other species (paleotropical or neotropical). Prior to this study, the range of distribution, southernmost and northernmost points and the fruiting time of S. sinensis were recorded, and the genus Sulzbacheromyces was firstly reported from Korean peninsula and Philippines.
Ascomycota
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Asia
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Basidiomycota
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DNA
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DNA, Ribosomal
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Ecology
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Fruit
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Geography
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Korea
;
Lichens
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Philippines
;
Phylogeny
;
South Africa
;
Trees
8.A Structural Equation Model of Happiness in Korean College Students
Journal of Korean Academy of Psychiatric and Mental Health Nursing 2019;28(2):181-189
PURPOSE: The aim of this study was to develop a structural model based on Bronfenbrenner's ecology of human development theory, that illustrates relationships of happiness and associated factors among Korean college students. METHODS: Study participants were 357 college students recruited from five universities throughout the convenience sampling. Self-reported data were collected from November, 2018 to January, 2019. The data were analyzed using descriptive statistics, Pearson's correlation coefficients, and a structural equation modeling in order to identify factors associated with college students' happiness. RESULTS: The tested model demonstrated the acceptable model fit compared to the hypothesized model, that explained college students' happiness with 68.7% accuracy. Positive family function, high self esteem and ego-resilience were significant factors associated with happiness for college students. However, positive friend support was not significant in our model. CONCLUSION: Our study findings suggest that both family and individual interventions are required to reduce negative emotions and increase happiness of college students. In particular, multicomponent interventions should include the concepts of self esteem, ego-resilience, and family function in terms of assessment and intervention contents tailored to Korean college students.
Ecology
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Ecosystem
;
Friends
;
Happiness
;
Human Development
;
Humans
;
Models, Structural
;
Self Concept
9.Diversity and Ecology of Myxomycetes from Kütahya and Konya (Turkey) with Four New Records.
Mycobiology 2018;46(3):215-223
In this study, we examined myxomycetes that developed in moist chamber cultures of substrata material collected from Kütahya and Konya provinces in Turkey. We collected bark samples from living trees, plant litter from the ground, standing dead wood or stumps, and downed and decayed wood or bark and placed them in the moist chamber cultures. We identified 36 species belonging to 12 genera of myxomycetes. The species determined are listed, and four new records, Didymium balearicum Ing, Macbrideola oblonga Pando & Lado, Paradiacheopsis erythropodia (Ing) Nann–Bremek. and Perichaena pedata (Lister & G. Lister) G. Lister, are added to the mycoflora of Turkey.
Ecology*
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Myxomycetes*
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Plants
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Trees
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Turkey
;
Wood
10.Research Progress on Leptotrombidium deliense
Yan LV ; Xian Guo GUO ; Dao Chao JIN
The Korean Journal of Parasitology 2018;56(4):313-324
This article reviews Leptotrombidium deliense, including its discovery and nomenclature, morphological features and identification, life cycle, ecology, relationship with diseases, chromosomes and artificial cultivation. The first record of L. deliense was early in 1922 by Walch. Under the genus Leptotrombidium, there are many sibling species similar to L. deliense, which makes it difficult to differentiate L. deliense from another sibling chigger mites, for example, L. rubellum. The life cycle of the mite (L. deliense) includes 7 stages: egg, deutovum (or prelarva), larva, nymphochrysalis, nymph, imagochrysalis and adult. The mite has a wide geographical distribution with low host specificity, and it often appears in different regions and habitats and on many species of hosts. As a vector species of chigger mite, L. deliense is of great importance in transmitting scrub typhus (tsutsugamushi disease) in many parts of the world, especially in tropical regions of Southeast Asia. The seasonal fluctuation of the mite population varies in different geographical regions. The mite has been successfully cultured in the laboratory, facilitating research on its chromosomes, biochemistry and molecular biology.
Adult
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Asia, Southeastern
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Biochemistry
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Ecology
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Ecosystem
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Host Specificity
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Humans
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Larva
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Life Cycle Stages
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Mites
;
Molecular Biology
;
Nymph
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Ovum
;
Scrub Typhus
;
Seasons
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Siblings
;
Trombiculidae

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