Telangiectasia macularis eruptiva perstans (TMEP) represents a rare form of cutaneous mastocytosis, which is clinically characterized by reddish-brown telangiectatic macules symmetrically distributed over the trunk and extremities. Although in the majority of cases the disease is limited to the skin, systemic involvement may occur. Treatment is often challenging due to lack of an established first-line therapy and as such is primarily focused on symptomatic relief. This case describes a 45-year-old Filipino Female with chronic refractory TMEP.

Human ; Female ; Middle Aged: 45-64 Yrs Old ; Mastocytosis, Cutaneous ; Telangiectasia Macularis Eruptiva Perstans

Nodular lesions in syphilis are typical of the late benign stage of the disease. It is a rare clinical manifestation of the said disease with a generalized distribution, involving both skin and mucous membranes. Lesions are more prominent on the upper extremities with a special predilection for the palms and the soles in the early stages. We present a case of a 25-year-old Filipino male with a 5-month history of generalized purplish to violaceous nodules with excoriations and scaling. When co-infected with advanced HIV it may present similarly as malignant secondary syphilis. After administration of Benzathine Penicillin G single dose IM, it is important to frequently assess these patients clinically and serologically for possible treatment failures at 3, 6, 9, 12, and 24 months after therapy.

Human ; Male ; Adult: 25-44 Yrs Old ; Aids ; Acquired Immunodeficiency Syndrome ; Hiv