1.Results of a study on the prevalence of pulmonary tuberculosis among people with type 2 diabetes mellitus
Tsetsegtuya B ; ; Oyuntuya T ; ; Narantuya G ; Ulzii-Utas A ; Davaadulam D ; Purevsuren B ; Bolortsetseg G ; Aigul U ; Lkhagvajav N ; Ermek J ; Tsolmon B ; Oyuntugs B ; Naranzul D ; Mitarai S ; Buyankhishig B ; Sarantuya J
Mongolian Journal of Health Sciences 2025;90(6):135-140
Background:
The continuous annual increase in the prevalence of diabetes mellitus (DM) poses significant challenges not
only within our nation but also globally in the control and management of tuberculosis.
Aim:
This study aimed to determine the incidence of pulmonary tuberculosis among individuals with type 2 diabetes
mellitus (T2DM) residing in six central districts of Ulaanbaatar and to investigate associated factors.
Materials and Methods:
A cross-sectional study design was employed. Participants aged 18 years and older diagnosed
with T2DM and receiving care at endocrinology clinics in six central districts of Ulaanbaatar were selected using systematic random sampling. Presumptive TB cases were identified through a structured questionnaire and chest X-ray. Sputum
specimens were collected and subjected to smear microscopy and Xpert MTB/RIF assay for tuberculosis detection. Cases
confirmed by laboratory diagnosis, currently undergoing tuberculosis treatment and previously treated cases as per questionnaire data were classified as tuberculosis cases, and prevalence was calculated.
Results:
A total of 1,644 individuals with T2DM were enrolled in the study, of whom 836 (50.9%) were female, with
a mean age of 58 years (range 19–89). The overall prevalence of presumptive TB cases was 10.5% (n=172; 95% CI,
9.0–12.0). Among 112 suspected cases from whom sputum samples were obtained, 10 (8.9%; 95% CI, 4.9–15.7) were
laboratory-confirmed for M.tuberculosis. Notably, 7.2% (6 cases; 95% CI, 3.4–14.9) of asymptomatic individuals with
abnormal X-ray findings were diagnosed with tuberculosis. According to questionnaire responses, 9 participants (0.5%;
95% CI, 0.3–1.0) were undergoing tuberculosis treatment, and 53 (3.2%; 95% CI, 2.5–4.2) reported a previously treated
TB cases. The overall prevalence of tuberculosis among individuals with diabetes was 4.4% (n=72; 95% CI, 3.5–5.5).
Stratification by age and sex revealed a significantly higher prevalence among males (5.9%; n=48; 95% CI, 4.5–7.8)
compared to females (2.9%; 95% CI, 1.2–4.2) (p=0.002), indicating a twofold increased risk of tuberculosis in males.
Although no statistically significant differences in tuberculosis prevalence were observed across age groups (p>0.05), a
declining trend in prevalence with older age was noted.
Conclusion
The prevalence of tuberculosis among individuals with type 2 diabetes was 4.4% (n=72; 95% CI, 3.5–5.5),
with a significantly higher rate in males (p=0.002) and a decreasing trend with increasing age. Among asymptomatic
individuals exhibiting radiographic abnormalities, 7.2% were confirmed to have tuberculosis via laboratory testing
2.ЭМНЭЛЗҮЙН УРЬДЧИЛАН ТООЦООЛОХ ДҮРМЭЭР НОЙР БУЛЧИРХАЙН ЦОЧМОГ ҮРЭВСЭЛТЭЙ ЭМЧЛҮҮЛЭГЧИЙН ТАВИЛАНГ ТОДОРХОЙЛОХ БОЛОМЖ
Dariimaa G ; Otgonjargal B ; Oyundari B ; Maral-Erdene D ; Tserennadmid Ts ; Davaadulam E
Innovation 2017;11(2):127-130
Нойр булчирхайн цочмог үрэвсэл, эмнэлзүйн урьдчилан тооцоолох дүрэм, Ranson –ийн шалгуур, APACHE II-ийн шалгуур
A clinical prediction rule is a type of medical research study in which researchers try to
identify the best combination of medical sign, symptoms, and other findings in predicting
the probability of a specific disease or outcome. More than 80% of all patients with
acute pancreatitis recover promptly without developing severe pancreatitis. The presence
of early organ failure (within 24 hours of admission), multiple-organ system failure,
and persistent or progressive (present beyond 48 hours after admission) organ failure are
associated with prolonged hospitalization, ICU admission, need for surgery, and death.
In high developed country, Ranson and APACHE II prognostic criteria are used in order
to evaluate patient´s situation and modified treatment tactics. That is give an idea us
to carry out retrospective study, by using patients´ documents, who hospitalized in National
central hospital in last year. As result, according to Ranson´s criteria 13 (31.7%) of
all patients had 0-2 score, which means mortality risk was 1.8%, 20 (48.8%) had 3-4 score
(mortality risk is 11%), 8 (19.5%) were estimated 5-6 score, having 33% of mortality risk.
Whereas, regarding to APACHE-II criteria 14 (34.2%) of total patients had score of 0-4,
showing 4% of mortality risk, 23 (56.1%) were scored 5-9, having 8% of risk, 3 (7.3%) were
scored 10-14, having 15% of risk, 1 (2.4%) had 15-19 score, having 24% of risk. Moreover,
we determined that incomplete laboratory test, meaning essential prognostic criteria
not used in Mongolia.
3.Lead residue and health risk in some commonly consumed imported food products among Mongolian population
Enkhtungalag B ; Gereljargal B ; Tuvshinbayar B ; Oyundelger D ; Unurtsetseg CH ; Davaadulam B ; Tserenlkham B ; Khishigtogtokh D ; Sodnomtseren B ; Jargal E ; Batkhishig O
Mongolian Medical Sciences 2014;168(2):71-76
IntroductionThe imported food products are more than 60 percent of total food consumption of Mongolia. Thelead residue in food products causes chronic and acute poisoning to the human health when exceedsmaximum residues limits, and human exposure and significant public health problems in many partsof the world.GoalTo assess lead residues and health risk of some commonly consumed imported food productsamong Mongolian population.Objectives:1. To determine consumption of some imported food products of Mongolian population;2. To investigate lead residue in some commonly consumed imported food products;3. To assess potential health risk related lead residue.Materials and MethodsThe research used analytic study of cross-sectional study design. Randomly selected 1290 people’simports food consumption was analyzed by questionnaire and body weight measurements. Tooksamples from 145 import products, identified lead residue with Academy of Sciences Soil ResearchLaboratory`s, ASS (USA, 2002) equipment.Results60.7% of imported food samples were lead residues exceeded to Maximum Residues Limits, suchus mean lead residues in meat product were 1.55 mg/kg, in milk product 1.22 mg/kg, in cerealproducts 1.15 mg/kg, in vegetables 1.57 mg/kg, in fruit and fruit juice 1.03 mg/kg, in alcohols drink1.31 mg/kg, and in tea 1.93 mg/kg (p=0.001). Estimated Provisional Tolerable Weekly Intake (PTWI)of lead exposure for survey responses was 0.079mg/kg body weight.Conclusions:1. 60.7% of imported food samples were lead residues exceeded to Maximum Residues Limits,such us mean lead residues in meat product, milk products, fruits and vegetables.2. Imported vegetables (54.0%), cereal 8.4% products (15.5%), fruit and fruit juice (11.8%), andmilk products (8.4%) is main contributing to lead residues in imported food.3. Estimated Provisional Tolerable Weekly Intake (PTWI) of lead exposure for survey responseswas 0.079mg/kg body weight, which is 3.2 times higher than toxicological guidance (PTWI 0.025mg/kg per 1 kg human body weight) and the high health risk level.
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