BACKGROUND: The prescriptions of multi-component have been the subject of chemical study fora long time. Therefore, when compounding the preparations of multi-component in traditionalmedicine, their taste is cautiously relied on, as the power of the medicine should not be subduedwith the power of another. Our research group has been carrying out tests on the raw materials,which are contained in multi-component prescriptions. However, research on multiple prescriptionsis relatively less being carried out.The traditional medicine naro-3 is used in traditionalmedical practicefor the treatment of inflammationand as a pain relieving remedy. Naro-3 is composed of 3 medicinal herbs including AconitumKuznezoffii Reichb, Terminalia chebula Retz, Piper longum L.GOAL: The aim of the study is to investigate some phytochemical compounds of traditional prescriptionNaro-3.OBJECTIVES:1. To reveal biological active substances of naro-3;2. The sum of the quantitative chemical study by spectrophotometry;3. To establish main criteria of standardMATERIALS AND METHODS: Traditional medicine narî-3 was produced from the Traditional Medicinefactoryof TMSTPC. In the phytochemical research, biological active substances were determinedby thin layer chromatography (TLC), on silica gel plats. The total contents of alkaloid and tannincompounds were determined by titrimetric method. TheMongolian pharmacopoeia was used fordetermination of quality parameters of traditional medicine Naro-3.RESULTS: TLC measurements of biological active substances of naro-3 showed that contains gallicacid and alkaloids respectively. The result of our research it was determined that the total tannin10.4 percent, total alkaloid 2.47 percent and organic acid 2.67 percent in drug Naro-3.CONCLUSION: The results of the study indicate that naro-3 contains a large amount of biologicalactive substances such as tannins, alkaloids and organic acids, which are connected with its painrelieving and anti-inflammatory effects.

Foreword: There is a demand to compare traditional medicine with modern medical science so that it will educate public for proper usage of natural traditional medicine such as main concept, identifying medical plants, reducing its volume, taste etc...1We mainly concentrated on comparisement of Mongolian religious healers books and chose following books for our research work that are “Thefour basic medicine” by Yutig Yondongombo Tibeten doctor and 2 other books by Mongolian doctor Luvsanchultem and Jambaldorj. Methods we used are analyzing, summarizing, comparing and classifying. According to a book “The four basic medicine” the animal starch includes horn, bone, meat, blood, gall, fat, brain, skin, nail, hair, urine, litter and body. Also, the book states their potential healing power. In a book named “Beautification” it says there are11 medicine comes from human and 124 medicine comes from animals and detailed classification is stated here. “Medicine identifying science” by Luvsanchultem Tsakhar gevsh (monastic title for a learned lama) says that there are 54 animal starch medicineand it shows us how to be aware of recognition and not to be mistaken. Here popular medicine are determined how to find out that is in good or bad condition, so that made it easier for us to identify and contributed greatly to Mongolian medical science.

Introduction:Influenza A viruses (IAV) are important pathogens that cause acute diseases in humans and domestic animals. In Mongolia only during 2010/2011 influenza season, there has been registered in average 1232 influenza like illness per 10.000 people, which is 5.8% of all the registered outpatient visits. Scutellaria baicalensis Georgi is one of the most widely used Mongolian Traditional Medicine that historically is used in anti-inflammation, anticancer, antiviral and antibacterial therapy. The goal of this study was to study antiviral effectiveness of Scutellaria baicalensis Georgi extract on the cells via in vitro. Methods:Water extracts of Scutellaria baicalensis Georgi were prepared from its rhizomes and herbs. To assess the antiviral properties, avian influenza virus isolate A/H3/Teal/Tunka/7/2010 was incubated at 37°C for 30min in presence and absence of plants and the drug extracts in various concentrations. Subsequently the concentration of infectious virus in each sample was determined by plaque assays. Neutralisation indexes and 90% plaque reduction concentrations had been estimated for each extract and significance of data obtained was evaluated using convenient statisticalmethods. Results:The extracts of Scutellaria baicalensis Georgi no significant toxicity, is well tolerated by Madin-Darby canine kidney cells at concentrations up to 1-0.25%. The extracts of Scutellaria baicalensis Georgi reduced the titer of A/Teal/Tunka/7/2010 (H3N8) by 50% (p≤0.05). The plaque reduction neutralization tests revealed that none of the extracts tested were able to inhibit 90% of plaques. However, extract ofScutellaria baicalensis Georgi, is able to inhibit more than 50% of plaques at low dilutions from 1:3 to 1:14 and the former two were expressing concentration- dependent inhibitory effect. Conclusion 1.Antiviral action of the extracts of Scutellaria baicalensis Georgiis detected. These extracts significantly reduced the infectiveness ofinfluenza A virus H3N8 in-vitro when used in high concentrations (1-0.25%). 2.Extract of Scutellaria baicalensis Georgi is well tolerated by Madin-Darby canine kidney cells at concentrations up to 0.94%.

IntroductionNowadays the risk factors for thrombosis include blood stasis, vessel wall injury, and hypercoagulability, as proposed by Virchow over 150 years ago. We chose to study affect of Zomoshin 6 tan to the model of thrombosis formed in experimental animal. It was written in books and sudar that it has action of treating some type’s disease such as blood diluting, meeting frozen blood and treating some gynecological disease.PurposeTo study affect of Zomoshin-6 tan deep vein thrombosis model formed in experimental animal.Material and Methods30 male rats of wistar bread with 180-220 gram of weight for control group, experimental group or Zomoshin-6 tan and comparative group Warfarin. Thirty rats were equally divided into 3 groups: Group 1 received saline alone, Group 2 received Zomoshin-6 (200 mg/kg), and Group 3 received Warfarin as a positive control (0.25 mg/kg), seven days prior to the assessment of thrombus formation. Thrombus formation was also assessed histopathologically. Thrombi were detected in all rats after experimentallyinduced thrombosis.ResultsHistological analysis demonstrated the presence of thrombosis in the interior vena cava (IVC) of the control group, which contained fibrin, erythrocytes, and leucocytes and obstructed the lumen. Only a small amount of fibrin clot, containing a few leucocytes and large numbers of erythrocytes, were observed in the Zomoshin-6-treated group. The thrombus formed in the IVC of Warfarin-treated animals consisted of fibrin clot, which was mostly attached to the wall, with few leucocytes but abundant erythrocytes. These findings suggest that Zomoshin-6 is an effective antithrombotic agent.Conclusion:Zomoshin-6 tan has an action of inhibing thrombosis forming of vein in experimental animal.

This study was carried out to investigate the pharmacological effects of aqueous extracts from the traditional Mongolian medicinal herb, the root of Caraganajubata pall poir, on liverfibrosisinduced carbon tetrachloride (CCl4) in rats. Liverfibrosis was assessed by histological observations and serum enzyme activities. Treatment with aqueous extract of Caraganajubata significantly reduced the levels of liver ASAT and ALAT. Aqueous extract of Caraganajubata root inhibits fibrosis and reduced serum enzyme in rat liverinduced by CCl4.

Introduction: There is an increasing need to study traditional medical sourcebooks and explanatory materials to enrich and develop medical concepts and clinical practices. Objectives: To study Mongolians contribution of nomenclature, origin andclassification of precious medicine using traditional medical sourcebooks and explanatory materials. Results and conclusion: The sourcebook “The Four Medical Tantras”written 10 type of jewel and the sourcebook “Em tanikh ukhaan”hadreferred mentioned above brass and plumbum. Although, this book determined jewel medicines shape, function and treatment, how to know these jewel.In the sourcebook “Uzesgelent nuden chimeg” jewel had divided an not fluxible-25, fluxible-13. These scientists medicinal prescriptions knowledge were shown greatly consideration in Mongolian traditional medicine.

Үе мөчний өвчин нь удаан явцтай ба урьдчилан сэргийлэх түүнчлэн тууштай эмчилгээ хийлгэхгүй бол хүндэрч хөдөлгөөний дутагдалд орох аюултай байдаг.Иймд өрний эмийн эмчилгээний зэрэгцээ хүний биед сөрөг нөлөө багатай ургамлын гаралтай эм бэлдмэл гарган авах, судлах ажил чухлаар шаардагдаж байна. Бид далан түрүү, урт навчит батраш, улаан чинжүүгээр найрсан үе мөчний бигнүүрийг судлагдахуун болгон авч эмнэл зүйн судалгааг УАШУТҮК-н амбулаториор эмчлүүлэхээр ирсэн 60 хүнд шавар эмчилгээтэй харüцуулан явууллаа. Судалгааны үр дүнд бигнүүр нь үрэвслийг дарахын зэрэгцээ хэсэг газрын үйлчлэлээрээ захын мэдрүүлүүдийг цочроож үений цусан хангамжинд нөлөөлж үрэвслийг дарах , өвдөлт намдаах, антиоксидант үйлдэл үзүүлдэг нь уг бигнүүрт агуулагдаж байгаа ургамлуудын биологийн идэвхит бодисуудын (флавоноид, кумарин, алкалоид, органик хүчил ) үйлчилгээг гаргаж чадаж байгааг баталж байна.

Introduction: The present work was focused on the investigation of resistance of biological membranes of various herbal formulations “Adapton 6” containing of rosa cinnamomea (плоды шиповника), Crataegus sanguine Pall (боярышника), Hippophae rhamnoides L (облепихи), radix Astragalus dasyanthus Pall (корни Астрагала) (левзеи) and Rheum palmatum L (ревеня).Purpose: study of evaluation of the membranostabilizing effect of “Adapton 6”Materials and Methods: in the experiment was made from 1% suspension of cleaned erythrocytes. The hemolisis of erythrocytes was induced by Phentona (peroxide hemolise) and added distilled water (osmotic hemolisis).Result: The membranostabilzing effect defined in vitro, according to the degree of bracing of peroxide and osmotic hemolisis of erythrocytes of donor’s blood 4. Suspension erythrocytes were taken with equal volume of distilled water to get osmotic hemolisis. The studied range of concentration of membranostabilizing effect of “Adapton 6” was 0.1 mkg/ml and reducing hemolisis in 64%, comparison with control group. In the studied drug were 1.0, 0.1and 0.01 mg/ml when degree of hemolisis reduced on 42. 52 and 60%, accordingly. The peroxide hemolise established that IC50 is 0.492 mg/ml (492 mkg/ml). Also in the studied drug were 1.0, 0.1 and 0.01 percent mg/ml when degree hemolisis reduced on 32, 49 and 51 respectively. The osmotic hemolise established that IC 50 is 0.6 mg/ml (60 mkg/ml). Conclusion: On conclusion, the prepared multicomponent herbal drug “Adapton 6” has membranostabilzing effect due to reduce of peroxide and osmotic hemolisis on the erythrocytes and degranulation adipocyates.