To summarize the clinical experience and characteristics of Professor XU Xin in syndrome differentiation and treatment of polycystic ovary syndrome with insulin resistance （PCOS-IR）. XU Xin believes that the etiological factors of PCOS-IR is qi deficiency of the spleen and kidney， and the key disease mechanism is dysfunction in transportation and transformation of spleen and kidney， causing phlegm dampness and turbid heat accumulated in yangming， then evolving into the lower jiao， mixed with blood stasis， finally obstructing the chong （冲） and ren （任） mai and uterus. So in clinic， the method of boosting the kidney and fortifying the spleen was used through out the whole treatment commonly using modified Shoutai Pill （寿胎丸） and Sijunzi Decoction （四君子汤）. The main therapeutic method for treating PCOS-IR refers to clearing and draining dampness heat in yangming， invigorating blood and regulating period， with self-prescribed Yishen Quzhuo Formula （益肾祛浊方）， as a reference for the treatment of this disease.

Traditional Chinese Medicine (TCM), as a treasure of the Chinese nation, plays a significant role in maintaining public health. In 2019, the Central Committee of the Communist Party of China and the State Council proposed for the first time the establishment of a TCM registration and evaluation evidence system that integrates TCM theory, "personal experience" and clinical trials (referred to as the "Three-in-One" System) to promote the inheritance and innovation of TCM. Subsequently, the National Medical Products Administration issued several guiding principles to advance the improvement and implementation of this system. Owing to the complexity of its implementation, there are still differing understandings within the TCM industry regarding the positioning of the "Three-in-One" Registration and Evaluation Evidence System, as well as the connotation and value orientation of the "personal experience." To address this, Academician WANG Qi, President of the TCM Association, China International Exchange and Promotion Association for Medical and Healthcare and TCM master, led a group of academicians, TCM masters, TCM pharmacology experts and clinical TCM experts to convene a "Seminar on Promoting the Implementation of the ′Three-in-One′ Registration and Evaluation Evidence System for Chinese Medicinals." Through extensive discussions, an expert consensus was formed, clarifying the different roles of the TCM theory, "personal experience" and clinical trials within the system. It was further emphasized that the "personal experience" is the core of this system, and its data should be derived from clinical practice scenarios. In the future, the improvement of this system will require collaborative efforts across multiple fields to promote the high-quality development of the Chinese medicinal industry.

To promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization, led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles, research experts in the field of herbal medicine and extracellular vesicles were invited nationwide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles, Professional Committee on Extracellular Vesicle Research and Application, Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal Vesicles. Based on the collation of relevant literature, we have adopted the Delphi method, the consensus meeting method combined with the nominal group method to form a discussion draft of "Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023)". The first draft was discussed in online and offline meetings on October 12, 14, November 2, 2022 and April and May 2023 on the current status of research, nomenclature, isolation methods, quality standards and research applications of extracellular vesicles of Chinese herbal medicines, and 13 consensus opinions were finally formed. At the Third Academic Conference on Research and Application of Chinese Herbal Vesicles, held on May 26, 2023, Kewei Zhao, convenor of the consensus, presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal Vesicles. The consensus highlights the characteristics and advantages of Chinese medicine, inherits the essence, and keeps the righteousness and innovation, aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad, decode the mystery behind Chinese herbal vesicles together, establish a safe, effective and controllable accurate Chinese herbal vesicle prevention and treatment system, and build a bridge for Chinese medicine to the world.

ObjectiveTo improve the quality standard of Yuanhu Zhitong oral liquid in order to strengthen the quality control of this oral liquid. MethodThin layer chromatography（TLC） was used for the qualitative identification of Corydalis Rhizoma and Angelicae Dahuricae Radix in Yuanhu Zhitong oral liquid by taking tetrahydropalmatine， corydaline reference substances and Corydalis Rhizoma reference medicinal materials as reference， and cyclohexane-trichloromethane-methanol（5∶3∶0.5） as developing solvent， Corydalis Rhizoma was identified using GF254 glass thin layer plate under ultraviolet light（365 nm）. And taking petroleum ether（60-90 ℃） -ether-formic acid（10∶10∶1） as developing solvent， Angelicae Dahuricae Radix was identified using a silica gel G TLC plate under ultraviolet light（305 nm）. High performance liquid chromatography（HPLC） was performed on a Waters XSelect HSS T3 column（4.6 mm×250 mm， 5 μm） with acetonitrile（A）-0.1% glacial acetic acid solution（adjusted pH to 6.1 by triethylamine）（B） as the mobile phase for gradient elution（0-10 min， 20%-30%A； 10-25 min， 30%-40%A； 25-40 min， 40%-50%A； 40-60 min， 50%-60%A）， the detection wavelength was set at 280 nm， then the fingerprint of Yuanhu Zhitong oral liquid was established， and the contents of tetrahydropalmatine and corydaline were determined. ResultIn the thin layer chromatograms， the corresponding spots of Yuanhu Zhitong oral liquid， the reference substances and reference medicinal materials were clear， with good separation and strong specificity. A total of 12 common peaks were identified in 10 batches of Yuanhu Zhitong oral liquid samples， and the peaks of berberine hydrochloride， dehydrocorydaline， glaucine， tetrahydropalmatine and corydaline. The similarities between the 10 batches of samples and the control fingerprint were all >0.90. The results of determination showed that the concentrations of corydaline and tetrahydropalmatine had good linearity with paek area in the range of 0.038 6-0.193 0， 0.034 0-0.170 0 g·L^-1， respectively. The methodological investigation was qualified， and the contents of corydaline and tetrahydropalmatine in 10 batches of Yuanhu Zhitong oral liquid samples were 0.077 5-0.142 9、0.126 1-0.178 2 g·L^-1， respectively. ConclusionThe established TLC， fingerprint and determination are simple， specific and reproducible， which can be used to improve the quality control standard of Yuanhu Zhitong oral liquid.

Under the backdrop of smart health management technology development, this article reviews research advances in smart monitoring, assessment and intervention technologies for older people with mild cognitive impairment, including the types, typical applications and results of monitoring, assessment and intervention technologies.In addition, from the perspective of community-dwelling older adults' cognitive health management, a model for innovative management of community-dwelling older adults' cognitive function taking advantage of smart health management technologies is proposed, aiming to enhance the acceptance of smart health technologies among older people with cognitive impairment and to provide policy advice on developing friendly communities for older people with cognitive impairment.

Objective To quantitatively analyze Chinese Healthy China initiative policies and provide a basis for the formulation and improvement of relevant policies.Methods The Healthy China initiative policies released at the national and provincial levels from 2016 to 2023 was selected as the research object.A PMC index model containing 9 primary variables and 42 secondary variables was constructed using text mining methods to evaluate the quality of the Healthy China initiative policies.Results Using 32 selected Healthy China initiative policies as sample policies,the average PMC index is 7.81,and the policy quality is good or above,at a moderate depression level.The PMC index average values of policy nature,policy content,and policy evaluation are relatively high in the primary variables,and the shortcomings of policy incentives and effectiveness levels are more obvious.Conclusion The overall coverage of the Healthy China initiative policies is relatively comprehensive,but there are still problems such as weak effectiveness levels,insufficient use of diverse incentives and corresponding policy tools,and uneven regional development.In the future,improvements should be made in terms of enriching effectiveness levels,balancing the use of policy tools,and strengthening inter regional exchanges and learning.

Zhuye Shigaotang is one of the 100 classic prescriptions published by the National Administration of Traditional Chinese Medicine. This study used the traceability method and bibliometrics method to analyze the main applicable syndromes， efficacy and meanings， modern disease spectrum， and other aspects of Zhuye Shigaotang， so as to further promote the research and development of this prescription. The results showed that Zhuye Shigaotang originated from the Treatise on Febrile Diseases， and its ingredients included Lophatheri Herba， Gypsum Fibrosum， Pinelliae Rhizoma， Ophiopogonis Radix， Ginseng Radix et Rhizoma， Glycyrrhizae Radix et Rhizoma， and Oryza sativa. The main applicable syndromes of Zhuye Shigaotang recorded in ancient books included heatstroke， cough and asthma， sores， sweat syndrome， hiccup， insomnia， malaria， headache， blood syndrome， nasosinusitis， laryngitis， etc.， involving diseases of internal medicine， surgery， gynecology， and pediatrics. Its pathogenesis was "incomplete residual heat， both Qi and Yin injuries， and stomach-Qi disharmony". The research found that Zhuye Shigaotang could also be used to treat acne， measles， and cholera， and it was especially suitable for the treatment at the later stage of epidemic diseases. Lophatheri Herba and Gypsum Fibrosum in the prescription could clear away heat and relieve vexation. Ginseng Radix et Rhizoma，Ophiopogonis Radix， Ginseng Radix et Rhizoma， and Oryza sativa could promote body fluid production and invigorate Qi. Pinelliae Rhizoma could harmonize the stomach and stop vomiting. The prescription had stable compatibility and had the effects of clearing away heat， relieving vexation， invigorating Qi， promoting body fluid production， and harmonizing the stomach. Zhuye Shigaotang was widely applied in modern clinical practices， with high application frequency in the digestive system， pediatric-related diseases， respiratory system， infectious diseases， circulatory system， and neuropsychiatric system. The specific symptoms included recurrent aphtha， hiccup， infantile pneumonia， infantile summer fever， unexplained fever， upper respiratory tract infection， epidemic hemorrhagic fever， and late measles.

Objective To quantitatively analyze Chinese Healthy China initiative policies and provide a basis for the formulation and improvement of relevant policies.Methods The Healthy China initiative policies released at the national and provincial levels from 2016 to 2023 was selected as the research object.A PMC index model containing 9 primary variables and 42 secondary variables was constructed using text mining methods to evaluate the quality of the Healthy China initiative policies.Results Using 32 selected Healthy China initiative policies as sample policies,the average PMC index is 7.81,and the policy quality is good or above,at a moderate depression level.The PMC index average values of policy nature,policy content,and policy evaluation are relatively high in the primary variables,and the shortcomings of policy incentives and effectiveness levels are more obvious.Conclusion The overall coverage of the Healthy China initiative policies is relatively comprehensive,but there are still problems such as weak effectiveness levels,insufficient use of diverse incentives and corresponding policy tools,and uneven regional development.In the future,improvements should be made in terms of enriching effectiveness levels,balancing the use of policy tools,and strengthening inter regional exchanges and learning.

Objective To quantitatively analyze Chinese Healthy China initiative policies and provide a basis for the formulation and improvement of relevant policies.Methods The Healthy China initiative policies released at the national and provincial levels from 2016 to 2023 was selected as the research object.A PMC index model containing 9 primary variables and 42 secondary variables was constructed using text mining methods to evaluate the quality of the Healthy China initiative policies.Results Using 32 selected Healthy China initiative policies as sample policies,the average PMC index is 7.81,and the policy quality is good or above,at a moderate depression level.The PMC index average values of policy nature,policy content,and policy evaluation are relatively high in the primary variables,and the shortcomings of policy incentives and effectiveness levels are more obvious.Conclusion The overall coverage of the Healthy China initiative policies is relatively comprehensive,but there are still problems such as weak effectiveness levels,insufficient use of diverse incentives and corresponding policy tools,and uneven regional development.In the future,improvements should be made in terms of enriching effectiveness levels,balancing the use of policy tools,and strengthening inter regional exchanges and learning.

Objective To quantitatively analyze Chinese Healthy China initiative policies and provide a basis for the formulation and improvement of relevant policies.Methods The Healthy China initiative policies released at the national and provincial levels from 2016 to 2023 was selected as the research object.A PMC index model containing 9 primary variables and 42 secondary variables was constructed using text mining methods to evaluate the quality of the Healthy China initiative policies.Results Using 32 selected Healthy China initiative policies as sample policies,the average PMC index is 7.81,and the policy quality is good or above,at a moderate depression level.The PMC index average values of policy nature,policy content,and policy evaluation are relatively high in the primary variables,and the shortcomings of policy incentives and effectiveness levels are more obvious.Conclusion The overall coverage of the Healthy China initiative policies is relatively comprehensive,but there are still problems such as weak effectiveness levels,insufficient use of diverse incentives and corresponding policy tools,and uneven regional development.In the future,improvements should be made in terms of enriching effectiveness levels,balancing the use of policy tools,and strengthening inter regional exchanges and learning.