1.Development and construction of comprehensive examination database for periodontology based on curriculum integration
Yiwei WANG ; Lizhen WANG ; Xi CHEN ; Ling ZHU ; Jian JIN ; Chaolun LI ; Rong SHU ; Yufeng XIE
Chinese Journal of Medical Education Research 2023;22(1):38-41
Periodontology is one of the important disciplines in oral clinical medicine, which covers a wide range of subjects and intersects with many basic disciplines. Under the environment of the implementation of modular teaching in Shanghai Jiao Tong University School of Medicine, the assessment method with separate propositions for the teaching and research section is still adopted. There is a mismatch between the assessment mode and the curriculum setting; the basic subject propositions are difficult to be combined with clinical cases; the knowledge point assessment is single, and the students' ability to integrate the knowledge points cannot be assessed. The development and construction of the comprehensive examination database for periodontology was based on curriculum integration, gathering the teaching backbones of various disciplines, focusing on periodontology, radiating all related disciplines, unifying the proposition outline, proposition type, proposition principle, combining with relevant knowledge points of various disciplines based on clinical cases, and tried to apply to clinical students majoring in stomatology. The use of the examination database promotes students' ability to flexibly apply theoretical knowledge to clinical case analysis, further promotes the reform of modular teaching, lays a solid foundation for future clinical work, and meanwhile provides an important basis for directions of the teaching and research section.
2.Tooth root resorption after guided tissue regeneration: A case report
Lan JIA ; Chaolun LI ; Wenjie ZHOU
Journal of Practical Stomatology 2018;34(2):280-282
This paper reports a case with severe chronic periodontitis who was eventually diagnosed with extensive internal and external apical root resorption due to the ineffective fixation of loose teeth after treatment by guided tissue regenaration.
3.The primary application of S-Detect technique in the diagnosis of thyroid tumors
Hong HAN ; Qing YU ; Lei ZHAO ; Longhui ZHANG ; Wenping WANG ; Chaolun LI ; Cong LI
Chinese Journal of Ultrasonography 2018;27(1):28-30
Objective To evaluate the value of S-Detect technology of ultrasonography in the diagnosis of thyroid tumors. Methods Ninety-three thyroid tumors in 93 patients were enrolled in the group.A varied image features of the thyroid masses in gray-scale ultrasonography were analyzed by S-Detect technology and experienced doctor separately.The results were compared and the diagnostic ability were also compared between the two methods. Results There were 44 malignant tumors and 49 benign tumors in these thyroid nodules.The sensitivity of S-Detect technology in the diagnosis of thyroid malignant tumors was higher,up to 88.7%. In the five image features of the thyroid tumors in gray-scale ultrasonography,the result of composition of the mass obtained by S-Detect was the most consistent with that of the doctors and Kappa value was 0.89.Conclusions S-Detect is a kind of computer-aided diagnosis system,which is suitable for the ultrasound beginners in the diagnosis of thyroid tumors.
4.Combined application of contrast enhanced ultrasound and dynamic contrast enhanced magnetic resonance imaging in hepatic epithelioid hemangioendothelioma
Yadan XU ; Wenping WANG ; Qun WANG ; Feng MAO ; Chaolun LI ; Min GUO ; Dong WU
Chinese Journal of Ultrasonography 2018;27(8):692-697
Objective To analyze the imaging characteristics of contrast-enhanced ultrasound(CEUS) and dynamic contrast enhanced magnetic resonance imaging ( CEMRI) for diagnosis of hepatic epithelioid hemangioendothelioma ,and to increase the accuracy of diagnostic imaging . Methods The imaging characteristics of CEUS and dynamic CEMRI in 11 patients with hepatic epithelioid hemangioendothelioma confirmed by surgical pathology or fine needle aspiration biopsy were retrospectively analyzed . Results On conventional ultrasound ,14 lesions in 11 patients showed hypoechoic . The peripheral blood flow was detected in most patients by color Doppler flow imaging and the average resistant index was 0 .62 ± 0 .05 . During the arterial phase ,6 lesions showed diffuse enhancement ,6 lesions showed annular enhancement and 2 lesions showed branch enhancement .As to time of peak enhancement ,compared to the normal hepatic parenchyma ,hypoenhancement ,isoenhancement and hyperenhancement were observed in 1 lesion ,7 lesions and 6 lesions respectively . Synchronous enhancement was observed in 8 lesions on contrast-enhanced ultrasound ,rapid enhancement was observed in 5 lesions and slow enhancement was observed in 1 lesion and all lesions decreased quickly in portal phase and delayed phase . On CEMRI ,all lesions showed low signal on TIWI ,high signal on T2WI and DWI . There were 5 lesions showed obvious annular constant enhancement and 1 lesion showed obvious annular progressive enhancement . Progressive peripheral enhancement and fully filling in delayed phase were found in 4 lesions .While progressive peripheral enhancement and incompletely filling in delayed phase were found in 3 lesions . One lesion displayed constant enhancement and incompletely filling in delayed phase . Halo sign" , lollipopsign" , capsular retraction sign" and vessel sign" were appeared in 6 ,7 ,8 and 8 patients respectively . Conclusions Both contrast-enhanced ultrasound and CEMRI have characteristic manifestations for the diagnosis of hepatic epithelioid hemangioendothelioma and cominbing them would be great significance to improve the preoperative diagnostic accuracy .
5.Diagnostic value of contrast-enhanced ultrasound for dysplastic nodule with a focus of hepatocellular carcinoma
Peili FAN ; Wenping WANG ; Jiaying CAO ; Feng MAO ; Zhengbiao JI ; Yi DONG ; Hong HAN ; Chaolun LI ; Lingli CHEN ; Yalan LIU
Chinese Journal of Ultrasonography 2018;27(12):1042-1047
Objective To investigate the imaging features of dysplastic nodules with a focus of hepatocellular carcinoma ( DN-HCC ) on contrast-enhanced ultrasound ( CEUS ) and to improve the diagnostic accuracy . Methods The clinical data of 60 patients and CEUS imaging of 62 hepatic nodules [DN-HCCs , n =54 ;dysplastic nodules (DN) , n =8] pathologically proved were reviewed retrospectively . According to Contrast Enhanced Ultrasound Liver Imaging Reporting and Data System (CEUS LI-RADS) , the lesions were categorized . Results Significantly different CEUS patterns between DN-HCCs and DNs were observed ( P < 0 .05) . During the arterial phase ,54 DN-HCC lesions showed various enhancement patterns [ hypervascular ,59 .3% ( 32/54 ) ;nodule-in-nodule ,9 .3% ( 5/54 ) ;isovascular ,13 .0% ( 7/54 ) and hypovascular ,18 .5% (10/54)] . Of the 54 DN-HCC lesions ,44 .4% (24/54) showed washout during the late phase .Of the 8 DN lesions ,62 .5% (5/8) showed iso-enhancement during the arterial phase ,25% (2/8) showed hypo-enhancement ,and 12 .5% (1/8) showed hyper-enhancement . No DN lesion showed washout during the late phase .According to CEUS LI-RADS (LR) algorithm ,27 .8% (15/54) DN-HCCs were LR-5 ,46 .3% (25/54) DN-HCCs were LR-4 ,25 .9% (14/54) DN-HCCs and 100% (8/8) DNs were LR-3 . Regarding hyper-enhancement ( including local hyper-enhancement ) during the arterial phase or hypo-enhancement (including local hypo-enhancement) during the late phase as the diagnostic standard of DN-HCC , the diagnostic sensitivity , specificity and accuracy value were 83 .3% , 87 .5% and 83 .9% , respectively . Conclusions The imaging features of hyper-enhancement during the arterial phase or hypo-enhancement during the late phase on CEUS are useful to diagnose DN-HCCs .
6.Clinical study of carotid artery contrast-enhanced ultrasonography in evaluating the activity of Takayasu's disease
Lingying MA ; Chaolun LI ; Xiufang KONG ; Xiaojie ZHANG ; Hong HAN ; Zhenqi DING ; Huiyong CHEN ; Beijian HUANG ; Lindi JIANG
Chinese Journal of Rheumatology 2017;21(11):748-753
Objective To observe the morphological changes of carotid artery wall by ultrasonography in patients with Takayasu arteritis,and to evaluate the diagnostic value of contrast-enhanced ultrasonography for active Takayasu arteritis.Methods High-frequency ultrasound technique was used to analyze the morphological changes of the carotid artery in 40 patients.NIH score was used as the gold standard and the complete clinical data and acute phase reactors were recorded.T test,Chi-square test,sensitivity and specificity were calculated for statistical analysis.Results The thickness of carotid artery wall in active group was much more thickened than the non-active group [(2.2±0.6) mm vs (1.8±0.5) mm,t=-2.142,P<0.05].The CDD [(0.89±0.06) in active group vs (0.95±0.03) in non-active group,t=3.683,P<0.01] and RDD [(0.17±0.06 in active group vs (0.09±0.05) in non-active group,t=-4.020,P<0.01] were significantly different between the two groups.The distribution of neovascularization in the carotid artery wall of the active group was more diffuse in the central part of the wall.The sensitivity and specificity of contrast-enhanced ultrasonography to diagnose the active of Takayasu arteritis were 72.7% and 87.5% respectively,and the positive predictive value and the negative predictive value were 80.0% and 82.4% respectively.Conclusion Contrast-enhanced ultrasonography can be used as an effective way to assess the disease activity of TA patients.
7.Epidemiological study on periodontal health status of medical students
Chaolun LI ; Dali LIU ; Yufeng XIE ; Zhongchen SONG ; Linhua GE ; Rong SHU
Journal of Shanghai Jiaotong University(Medical Science) 2017;37(4):545-550
Objective·To investigate and analyze periodontal health knowledge and behaviors in medical students and the relationship of these knowledge and behaviors with periodontal health status, and to determine the periodontal health level of this population. Methods·A total of 602 medical students were included in this cross-sectional epidemiological study. The questionnaire covered sociodemographic information, periodontal health-related behaviors and knowledge, experience about themselves, and periodontal health of parents, etc. Meanwhile, periodontal health indices of index teeth were examined, including probing depth (PD), clinical attachment loss (CAL), and bleeding on probing (BOP), etc. Results·Of 570 subjects aged 16-26 who completed the survey, 79.82% never used dental floss, and 78.25% never underwent periodontal debridement. 50.25% of the index teeth had BOP, and only 0.70% of the subjects had no BOP. 81.05% of the subjects had some degree of periodontal attachment loss. Male students were more susceptible to periodontitis (P=0.027) and gingivitis (P=0.012) than female students. Conclusion·No new risk factors affecting the periodontal health are identified. Regular periodontal cleaning and protection are important for young people to prevent periodontitis.
8.The applied anatomy study of vertebral basilar artery
Xiaoming FU ; Zhiqiang CHEN ; Chaolun WEN ; Yanbin LI
Journal of Chinese Physician 2015;17(1):37-40
Objective To observe the vertebrobasilar artery and its branch courses,diameters and the included angles in the starting part,offering morphological basis for clinic intervention and vascular image.Methods Layer by layer dissecting head,neck and chest of nine adult specimens affused with red latex,and after affused carotid artery with red latex,the origin,course,branches,distribution,anastomosis,and accompanying of the vertebrobasilar artery were observed in three normal adult corroded specimens.Results The degree of the left included angle between subclavian artery and vertebral was (91.70 ± 0.90) ° and that of the right one was (115.80 ± 1.60) ° (P < 0.05).A percentage (14.1%) of them contacted with vagus and glosssopharyngeal nerve.The degree of the left included angle between posterior cerebal lower artery and vertebral artery was (118.60 ± 3.70) ° and that of the right one (77.60 ± 7.90) °.A percentage (27.6 %) of itself contacted or pressed by root of facial nerve.The degree of the included angle on the left side between anterior cerebellar lower artery and brobasilar artery was (91.60 ± 2.40) ° and that of the right one was (27.10 ±2.70)°(P <0.05).The degree of the left included angle between posterior cerebral artery and basilar artery was (93.90 ± 3.40) ° and that of its right one was (130.80 ± 3.20) ° (p < 0.05).Conclusions Both vertebral artery in every part out of skull and the data of the each branch pipe diameter,the starting included angle of vertebrobasilar artery had statistical significance,which should select personalized catheter or operation method in endovascular intervention or craniocervical surgery.
9.Diagnostic value and characterization of contrast enhanced ultrasound for hepatic giant hemangionmas
Liang FANG ; Wenping WANG ; Yue CHEN ; Beijian HUANG ; Hong DING ; Feng MAO ; Chaolun LI
Chinese Journal of Ultrasonography 2015;24(3):232-236
Objective To explore the enhancement pattern and characterization of hepatic hemangionmas with contrast enhanced ultrasound (CEUS).Methods A total of 44 patients with 49 nodules preliminary diagnosed of liver hemangioma were included in this study.For each nodule,the enhancement pattern,level,and dynamic change of CEUS were evaluated,and the features of hemangionmas were groups as echoic and compared with those on CEUS.Results All hemangiomas enhanced in arterial phase with centripetal progression in venous and late phase on CEUS,among which 41 lesions showed peripheral nodular enhancement while 8 showed peripheral rim-like enhancement.The whole-tumor enhancement pattern was seen in 13 lesions and part-tumor enhancement was shown in 36 lesions.The performance of part-tumor was independent of tumor echoic and hypoechoic tumors mostly presented to be whole tumor enhancement pattern.During portal venous and late phase,42 lesions showed hyperenhancement,while 7 lesions showed isoenhancement.Conclusions CEUS can suggest the enhancement dynamic characters of hepatic giant hemangionmas and reveals the relationship of grey-scale echoic and enhancement pattern of hemangiomas.It is important to diagnose the hepatic giant hemangionmas for CEUS.
10.Value of Color Doppler Ultrasound in the Evaluation of Carotid Artery Restenosis after Carotid Artery Stenting or Carotid Endarterectomy
Xiting XU ; Chaolun LI ; Wanyuan HE ; Wenping WANG ; Xiyuan LIN
Chinese Journal of Clinical Medicine 2014;(3):301-303
Objective:To investigate the value of color Doppler ultrasound in the evaluation of carotid artery restenosis after ca-rotid artery stenting (CAS) and carotid endarterectomy (CEA) .Methods :A total of 53 patients with 62 carotid artery stenosis diagnosed by digital subtraction angiography (DSA) were enrolled .All of them underwent CAS and CEA .The postoperative and preoperative ultrasound datum including the minimum luminal diameter ,the peak systolic velocity (PSV )of the internal ca-rotid artery (ICA) and common carotid artery (CCA) ,end diastolic velocity (EDV) of ICA were retrospectively analyzed . Results:A total of 52 arteries were normal or had <50% restenosis ,while 10 arteries had ≥50% restenosis after the treat-ment .Compared with those before treatment ,the minimum luminal diameter was significantly wider ,and PSVICA decreased significantly in patients with <50% restenosis(P<0 .01) ,whereas the minimum luminal diameter and PSVICA were not sig-nificantly changed in patients with≥50% restenosis(P>0 .05) .PSVICA ,EDVICA and PSVICA/PSVCCA in patients with≥50% restenosis significantly increased compared with that in patients with <50% restenosis(P<0 .01) .PSVICA/PSVCCA≥2 was set as the cut-off point ,the sensitivity and specificity for detecting ≥50% restenosis were 80 .0% and 98 .1% respective-ly .Conclusions :Color Doppler ultrasound can effectively evaluate carotid artery restenosis after CAS or CEA .

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