1.Experiences of prevention and control of hospital infection in the emergency wards:the designated hospital treating new novel coronavirus disease in Shanghai as an example
Lan-ying LI ; Yin XU ; Lei SHI ; Bang-fang WANG ; Yong-jun TANG ; Jian-liang ZHANG
Shanghai Journal of Preventive Medicine 2020;32(9):746-
		                        		
		                        			
		                        			Since the outbreak of novel coronavirus pneumonia, the World Health Organization and the National Health Commission have issued multiple guidance documents.Medical facilities across the nation have actively implemented the countermeasures in response to the epidemic.However, in the real scenario of prevention and control, hospital infection remains a great concern.It is crucial to formulate measures and procedures based on standard prevention and transmission route prevention to avoid cross infection between medical workers and patients.Based on the practice, we summarize the institutional management, layout process, prevention and control of hospital infection in the emergency wards for further discussion and improvement.
		                        		
		                        		
		                        		
		                        	
2.Comparative study of perpendicular versus parallel double plating methods for type C distal humeral fractures.
Xia LAN ; Li-Hai ZHANG ; Sheng TAO ; Qun ZHANG ; Xiang-Dang LIANG ; Bang-Tuo YUAN ; Wen-Peng XU ; Peng YIN ; Pei-Fu TANG
Chinese Medical Journal 2013;126(12):2337-2342
BACKGROUNDDouble plate osteosynthesis is the standard treatment for intra-articular fractures of the distal humerus. However, there is still controversy concerning dual plate positions in terms of providing optimal stability. The purpose of this retrospective study was to compare the clinical outcomes in patients with type C intra-articular distal humeral fractures using perpendicular and parallel plating methods.
METHODSBetween March 2008 and June 2011, a total of 45 patients with type C distal humerus fractures were treated using two different dual plating methods. Of them, 24 patients were treated by perpendicular plating (group I) and 21 patients were treated by parallel plating (group II). The surgical time, blood loss, and union time were compared between the two groups. The flexion-extension arc, the total range of flexion and extension at the end of follow-up were compared between the two groups. The Mayo Elbow Performance Score (MEPS) was used to determine the elbow functional results.
RESULTSAll patients were followed up. The mean duration of follow-up was 16 months (range 12 - 25 months) in group I and 15.5 months in group II (range 12 - 25 months). There were no significant differences in the surgical time, blood loss, and the bone union time between the two groups. In group I, the mean elbow flexion-extension arc was 101° and the mean MEPS was 85 points. The rate of excellent and good results was 87.5%. In group II, the mean flexion-extension arc was 100° and the mean MEPS was 86.1 points. The rate of excellent and good results was 90.5%. There were no significant differences in the MEPS, flexion-extension arc, and the total range of flexion and extension between the two groups.
CONCLUSIONSPerpendicular and parallel plate configurations with the appropriate surgical techniques can provide anatomical reconstruction and stable fixation of type C intra-articular distal humeral fractures and allow early mobilization of the elbow after an operation. The occurrence of post-operative elbow stiffness can be reduced and good outcomes can be obtained.
Adult ; Aged ; Bone Plates ; Female ; Fracture Fixation, Internal ; methods ; Humans ; Humeral Fractures ; surgery ; Male ; Middle Aged ; Retrospective Studies
3.A survey on the agricultural profession-related injuries among 11 902 rural residents in Shandong province
Zhi-Hua LI ; Wei-Qing YIN ; Hong MA ; Wei-Liang LIU ; Sha-Sha LI ; Meng-Lin ZHANG ; Wen-Jie CHU ; Bang AN
Chinese Journal of Epidemiology 2011;32(8):768-772
		                        		
		                        			
		                        			Objective To understand the prevalence and risk factors of agricultural activities related injuries among rural residents in Shandong province. Methods A retrospective investigation was conducted among agricultural profession-related workers in 20 villages with multistage cluster sampling method in Shandong province. Four times face-to-face interview were conducted by trained interviewers, including 32 students and local medical personnel under constructed questionnaires.Accidental injuries occurred in the activities or in the agricultural profession-related jobs were recorded, from May 1st 2009 to April 30st 2010. Data was input and analyzed by SPSS 13.0 statistical software. Results A total of 837 cases reported at least 1 job-related injury out of the 11 902 people who had been surveyed in one year. The crude incidence rate was 7.03% and the standardized incidence rate was 7.36%, higher in males (9.01%) than in females (4.10%), X2= 105.53, P=0.000.Children and adolescents (≤ 14 aged) had the higher incidence rate (9.50%), X2=9.70, P=0.008.People working in the area of commercial service related to agricultural products had the highest incidence rate (12.94%). In particular, those occupations that related to agricultural construction or materials appeared to have had higher incidence rates as 16.80% and 15.59% respectively, than other kinds of jobs (X2= 167.30, P=0.000). There were higher proportion of injuries occurred in the roads (28.79%), in the fields(28.08%) during labor work(38.00%) transportation(27.97%), respectively.The seasonality of agricultural injures mostly occurred between June and August, accounted for 47.43%. Major external causes related to injuries were instruments or tools (31.42%) being used,transportation (24.13%) and falls (20.19%). Wounds on limbs took the majority (56.39%). The accidental self-inflicted injury occupied 76.82%, while accidents to passive injuries occupied 11.47%,other kinds accounted for 11.71%. Most of the accidents caused mild or moderate damage, accounted for 60.22% and 30.34% respectively. 7 cases died of injuries, with the fatality rate as 0.84% and the mortality rate was 58.81 per one hundred thousand. 72 cases ended up in disability caused by injuries,with the morbidity rate as 6.05 per thousand. Answers to the major internal causes of injuries appeared to be: "did not know how to protect oneself" (29.87%) with females (45.41%) in particular,followed by "over fatigue" and "inappropriate treatment" which took the 2nd place in males. Major natural environmental factors of injuries would relate to "high air temperature and humidity but lower wind velocity"(14.93%), "unclear signs on the country road"(12.19%), "the sky was cloudy or dark"(10.87%), "slippery road caused by rain or snow" (10.51%), "kids were unintended" (10.27%) etc.Most of the wounded received treatment clinically (50.18%), with the percentile (P50) of medical cost as 182.76 RMB (Yuan). The proportion of inpatient was 27.72% and with percentile of time as P50=7.57 day and cost as P50=2840.00 RMB Yuan. The wounded had a rest of P50=5.9 days, with an indirect cost as P50=233.16 RMB Yuan. Conclusion The results of this study indicated that the incidence of agricultural profession-related injuries was high, with serious harm. Behavioral intervention and awareness of injuries should be enhanced, together with the improvement of environmental condition.
		                        		
		                        		
		                        		
		                        	
4.NUSS procedure by video-assisted thoracoscopy for correction of pectus excavatum.
Wen-liang LIU ; Feng-lei YU ; Bang-liang YIN
Journal of Central South University(Medical Sciences) 2008;33(5):443-447
		                        		
		                        			OBJECTIVE:
		                        			To review the management of NUSS procedure by video-assisted thoracoscopy for the correction of pectus excavatum in 18 patients, and to prevent and treat some complications.
		                        		
		                        			METHODS:
		                        			Eighteen patients with severe pectus excavatum underwent NUSS procedure by video-assisted thoracoscopy from December 2006 to September 2007.
		                        		
		                        			RESULTS:
		                        			The operation time ranged from 30 to 70 min ( average 45 min). Good Results were achieved for all patients after the operation. All of them recovered and were discharged 5 approximately 7 days after the operation. Minor complications occurred in 2 patients.
		                        		
		                        			CONCLUSION
		                        			NUSS procedure is microinvasive and has beautiful outlook with shorter operation time and simple handling.The minimally invasive technique has a low complication rate with satisfactory short-term result. Proper management is important for the recovery at the early postoperative stage.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Child, Preschool
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Funnel Chest
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Minimally Invasive Surgical Procedures
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Thoracic Surgery, Video-Assisted
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Thoracic Surgical Procedures
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Thoracoscopy
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
5.Retrospective study on clinical application of biovalves in 52 cases.
Feng LI ; Jian-guo HU ; Bang-liang YIN ; Jin-fu YANG ; Tao TANG ; Hua GAO
Journal of Central South University(Medical Sciences) 2008;33(3):257-261
		                        		
		                        			OBJECTIVE:
		                        			To summarize the clinical application of bioprosthetic valve replacement.
		                        		
		                        			METHODS:
		                        			Fifty two patients, aged 13-73(52.4+/-14.0) years, underwent cardiac valve replacement with biovalves from June 2002 to June 2006 in our hospital. Fifty three tissue valve replacements combined with 8 mechanical valve replacements were performed. Other procedures were also carried out if appropriate, including bidirectional Glenn shunt in 1 patient with double outlet of right ventricle and pulmonary artery stenosis; interruption of accessory pathway in 1 patient with Wolff-Parkinson-White syndrome; coronary artery bypass graft in 5 with severe coronary artery disease; and atrial or ventricular repair in 4 with congenital septum defects.
		                        		
		                        			RESULTS:
		                        			One patient died in hospital due to multiple organ failure. The hospital mortality rate was 1.9%. The mean follow-up was 25 months. Two patients lost follow-up and the follow-up rate was 96%. Forty one patients returned to NYHA class I, 9 to class II, and 1 to class III. Echocardiography showed the implanted bioprosthesis functioned well without stenosis or regurgitation. There was no structural deterioration with freedom from thromboembolism and anticoagulant hemorrhage in all patients.
		                        		
		                        			CONCLUSION
		                        			The efficacy of biovalves in heart valve replacement is satisfactory.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Bioprosthesis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Heart Valve Prosthesis
		                        			;
		                        		
		                        			Heart Valve Prosthesis Implantation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Mitral Valve
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Tricuspid Valve
		                        			;
		                        		
		                        			surgery
		                        			
		                        		
		                        	
6.Integrated mediastinal pleura upon aortic arch and left cervical anastomosis in radical operation for esophageal carcinoma.
Yun-chang YUAN ; Jian-guo HU ; Feng-lie YU ; Bang-liang YIN
Journal of Central South University(Medical Sciences) 2008;33(1):78-80
		                        		
		                        			OBJECTIVE:
		                        			To evaluate the therapeutic effect of remaining integrated mediastinal pleura upon the aortic arch and performing the anastomosis at the left cervix in radical operation for esophageal carcinoma.
		                        		
		                        			METHODS:
		                        			Ninety-eight patients with esophageal carcinoma were treated with the operation mentioned above. Among them, 56 patients had cancer in the middle, 12 in the upper-middle, 24 in the lower-middle segments, and 6 had double-primary tumors, with carcinoma length of (5.2+/- 2.4) cm. The TNM stages were 6 of Stage I and 92 of Stages II-III. All cases were squamous cell carcinomas.
		                        		
		                        			RESULTS:
		                        			All patients had satisfactory operation processes, without perioperative death, chylothorax, dyspnea, gastric retention, incision infection, and severe gastro-esophageal reflux. The life quality of the patients was improved.
		                        		
		                        			CONCLUSION
		                        			The radical operation with remaining integrated mediastimal pleura upon the aortic arch and anastomosis at the cervix for treating esophageal carcinomas is of minimal invasion with fewer complications, and may be used in clinical practice.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Anastomosis, Surgical
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Aorta, Thoracic
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Carcinoma, Squamous Cell
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Esophageal Neoplasms
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pleura
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Thoracic Surgical Procedures
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
7.Connective tissue growth factor and pulmonary allograft fibrosis in rats.
Yun-chang YUAN ; Dian-jun WANG ; Bang-liang YIN
Journal of Central South University(Medical Sciences) 2007;32(5):873-876
		                        		
		                        			OBJECTIVE:
		                        			To investigate the role of connective tissue growth factor (CTGF) in pulmonary allograft fibrosis in rats.
		                        		
		                        			METHODS:
		                        			The lungs of 20 Wistar rats were transplanted into 20 Sprague-Dawley(SD) rats. Ten allograft lungs were harvested 1 week postoperatively (acute rejection group,AR); the other 10 allografts were harvested 6 weeks postoperatively (chronic rejection group,CR); and ten normal Wistar rats served as a control group(normal lung, NL). Paraffin embedded sections of the harvested lung specimens were stained with hematoxylin and eosin (HE), Van Gieson (VG) for the examination of tissue morphology under the microscope. The scores of lung fibrosis were measured and the wet/dry ratio of the lung specimens was evaluated. The CTGF expression was determined by immunohistochemical method.
		                        		
		                        			RESULTS:
		                        			The wet/dry ratios of lung decreased gradually(AR group vs. control group: 3.48+/-0.47 vs. 4.67+/-0.51, P<0.05; CR group vs. AR group: 2.85+/-0.52 vs. 3.48+/-0.47, P<0.05). The transplanted lungs showed massive lymphocytic infiltration, interstitial fibrosis, destroyed alveolus architecture, obliterative bronchiolitis, and lung tissue consolidation. These pathological changes were more severe in the CR group than in the AR group, but there were no such changes in the control group (scores of pulmonary fibrosis: NH, 0.00+/-0.00; AR, 0.98+/-0.47; CR, 2.35+/-0.52; AR vs. NH, P<0.01; CR vs. AR, P<0.01). CTGF was not expressed in the normal rat lungs (0.00+/-0.00); however, it was detected in the lung allograft after the operation. The CTGF expression in the CR group was significantly higher than that in the AR group (P<0.01).
		                        		
		                        			CONCLUSION
		                        			The expression of CTGF protein is related to the transplanted pulmonary fibrosis,and is involved in the pathogenesis of transplanted pulmonary fibrosis.
		                        		
		                        		
		                        		
		                        			Allografts
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Connective Tissue Growth Factor
		                        			;
		                        		
		                        			metabolism
		                        			;
		                        		
		                        			Fibrosis
		                        			;
		                        		
		                        			Lung
		                        			;
		                        		
		                        			metabolism
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Lung Transplantation
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Pulmonary Fibrosis
		                        			;
		                        		
		                        			metabolism
		                        			;
		                        		
		                        			Rats
		                        			;
		                        		
		                        			Rats, Sprague-Dawley
		                        			;
		                        		
		                        			Rats, Wistar
		                        			
		                        		
		                        	
8.Structural and hemodynamic study of right ventricular outflow tract reconstruction with valved bovine jugular vein conduit in the canine model by color Doppler echocardiography.
Xin-Hua XU ; Zhong-Shi WU ; Bang-Liang YIN ; Jian-Guo HU ; Yi-Feng YANG
Journal of Central South University(Medical Sciences) 2007;32(4):599-603
		                        		
		                        			OBJECTIVE:
		                        			To observe the structural and hemodynamic changes after the reconstruction of right ventricular outflow tract (RVOT) with valved bovine jugular vein conduit (BJVC) in the canine model by color Doppler echocardiography (UCG).
		                        		
		                        			METHODS:
		                        			BJVC was used in the reconstruction of RVOT of 32 canines. UCG was used to observe the structure of the right ventricle and RVOT. The structure and hemodynamics were observed, and the diameter, width, blood velocity and pressure gradient (PG) were measured between the right ventricle and the conduits.
		                        		
		                        			RESULTS:
		                        			In the first stage, UCG showed that PG between the right ventricle and BJVC was high in 5 canines, and a few anastomosis in BJVCs with main pulmonary artery was small. Blood velocity quickened and PG increased, and color Doppler showed that the bloodstream was very bright. In the second stage, 7 canines survived for 1 year after the implantation. One year after the operation, UCG showed that the valve closed well, no graft kinking or obvious regurgitation of the valve was observed. The PG of the valve was low. The BJVCs were unobstructed and there was no thrombus.All the valves of BJVC opened well except one. In the third stage, 20 canines survived for 1 year after the implantation. UCG showed that the valve motion was good, no graft kinking or obvious regurgitation of the valve was observed. No neoplasm was observed.
		                        		
		                        			CONCLUSION
		                        			UCG is one of the most useful measurements in the structural and hemodynamic study of RVOT reconstruction by BJVC in the canine model. The good evaluation of UCG implies that it is important for the study and clinical practice.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Blood Vessel Prosthesis
		                        			;
		                        		
		                        			Cattle
		                        			;
		                        		
		                        			Dogs
		                        			;
		                        		
		                        			Echocardiography, Doppler, Color
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Ventricles
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Jugular Veins
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			transplantation
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Pulmonary Artery
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			surgery
		                        			
		                        		
		                        	
9.Surgical treatment of total anomalous pulmonary venous connection.
Liang CAO ; Jian-Guo HU ; Yi-Feng YANG ; Jin-Fu YANG ; Bang-Liang YIN ; Xin-Min ZHOU ; Zhong-Shi WU ; Jian LIU
Journal of Central South University(Medical Sciences) 2007;32(4):542-545
		                        		
		                        			OBJECTIVE:
		                        			To summarize the surgical treatment of total anomalous pulmonary venous connection (TAPVC).
		                        		
		                        			METHODS:
		                        			We retrospectively analyzed 49 patients with TAPVC as follows: 37 patients with supra-cardiac type in which 35 received anastomoses between the rear wall of the left atrium and the common pulmonary vein and the other 2 received anastomoses between the rear edge of the left atrium roof and the common pulmonary vein; another 12 patients with cardiac type who were incised the upper edge of coronary sinus, connected the common junction of pulmonary veins with the left atrium to form a new left atrium, and repaired the atrial septal defect with a pericardial patch.
		                        		
		                        			RESULTS:
		                        			Forty-six patients recovered and 3 patients died. Thirty-eight patients were followed-up from 3 months to 8 years. The rest patients got fluent pulmonary vein drainage and their heart function resumed to NYHA I.
		                        		
		                        			CONCLUSION
		                        			TAPVC patients should be operated on immediately at definite diagnosis. The fluency of the common pulmonary vein-left atrium anastomoses and proper postoperative care can ensure a satisfactory outcome.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Anastomosis, Surgical
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Child, Preschool
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Infant, Newborn
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Pulmonary Veins
		                        			;
		                        		
		                        			abnormalities
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
10.Multifactor analysis of postoperative mechanical ventilation supporting time in infants with congenital heart diseases.
Jin-Lan CHEN ; Yi-Feng YANG ; Jian-Guo HU ; Bang-Liang YIN ; Qi-Hua GONG ; Xin-Hua XU
Journal of Central South University(Medical Sciences) 2007;32(2):328-332
		                        		
		                        			OBJECTIVE:
		                        			To analyze the multiple factors affecting the postoperative mechanical ventilation supporting time in infants less than 10 kg with simple congenital heart diseases and to seize time by the forelock of extube and improve the outcome of surgical treatment.
		                        		
		                        			METHODS:
		                        			Data of 231 infants less than 10 kg with atrial septal defect(ASD),ventricular septal defect, and combining patent ductus arteriosus were retrospectively analyzed. The multivaricate stepwise logistic regression statistics were done for the predisposing factors affecting the ventilative supporting time.
		                        		
		                        			RESULTS:
		                        			The ventilative supporting time was 3~375 (average 23.5 h) h. The multivaricate stepwise logistic regression analysis indicated that severe pulmonary hyperpressure, cross-cramp aortic time, cardiopulmonary bypass time, preoperational pulmonary infection, membrane oxygenator, modified ultrafiltration, weight, and postoperative complications were significantly correlated to the ventilative supporting time.
		                        		
		                        			CONCLUSION
		                        			Severe pulmonary hyperpressure, preoperational pulmonary infection, long cross-cramp aortic time, long cardiopulmonary bypass time, postoperative complications all prolong the ventilation supporting time; the use of membrane oxygenator and modified ultrafiltration during the operation and big weight can diminish the pulmonary complications and shorten the ventilation supporting time.
		                        		
		                        		
		                        		
		                        			Cardiopulmonary Bypass
		                        			;
		                        		
		                        			Child, Preschool
		                        			;
		                        		
		                        			Ductus Arteriosus, Patent
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Defects, Congenital
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Heart Septal Defects, Atrial
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Heart Septal Defects, Ventricular
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Logistic Models
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Multivariate Analysis
		                        			;
		                        		
		                        			Postoperative Period
		                        			;
		                        		
		                        			Respiration, Artificial
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Time Factors
		                        			
		                        		
		                        	
            
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