Background: Coronavirus illness (COVID-19) reached the level of a significant public health emergency in 2019, with an estimated worldwide death toll of more than 1,00,000 people 2019. Coronavirus illness (COVID-19). This survey was conducted to identify the factors influencing COVID-19 practice among undergraduate nursing students at the University of Nizwa, Sultanate of Oman. Methods: A quantitative cross-sectional online survey of sixty-four undergraduate nursing students chosen from the school of Nursing at the University of Nizwa in Sultanate of Oman took part from July 30 to August 5, 2021. Results: Participants’ average age was 22.27 ± 1.04, and the male-to-female ratio was 31.8% (n=64). Nursing students had adequate knowledge (13.67 ± 3.46), a positive attitude (48.14 ± 12.29), and good practices (32.6 ± 6.12), according to the results of a survey. Female students, compared to males (0.006, p<0.05), were more likely to follow better practices. Significant positive associations were found between age (0.025, p<0.05), gender (0.006, P<0.05), living areas (0.031, p<0.05), grade (0.000, p<0.05), Clinical practice experienced (0.016, p<0.05) and practice on COVID -19. Conclusions The study findings exhibited the essential elements that affected COVID-19 precautionary practices, knowledge, and a positive attitude, which were the most critical variables to consider. Male students and students who reside in rural regions should be targeted for further health education, and efforts should be made to ensure these groups have access to reliable and effective online tools to assist them.

Backgroun: Social media tends to cause poorer physical and mental health. Students are more addicted to using media in their daily lives and are more likely to stress. Objective: This study's primary objective is to explore the current level of knowledge of cyber bullying and provide awareness programs to bolt their reflective minds with possible coping strategies to prevent consecutive reduction behaviours among students of Aysha Al- Riyamia school in Bahla. Methods: One hundred eighty participants were recruited from Aysha Al- Riyamia school in Bahla in grades 10 through 12 using a convenient sampling technique. The questionnaire was constructed with knowledge and coping skills about cyber bullying and adopted to collect data from the participants before and after an educational awareness program. Results: The results showed that awareness programs had significantly enhanced students' knowledge and coping strategies in cyber bullying. Furthermore, the evidence of the study confirmed that cyber bullying awareness programs had a positive influence on knowledge among school students; the mean difference between pre-test and post-test was 2.81 at p<0.05. Conclusion Given the widespread use of social media in everyday life, these findings highlight the need for more incredible research into the education program to minimize the risks involved in cyber bullying.

Purpose: One of the essential goals regarding the successful control of rabies infection is the development of a safe, effective, and inexpensive vaccine. the current study aimed to evaluate the inactivation potential of β-propiolactone (βPL), binary ethyleneimine (BEI), and hydrogen peroxide (H2O2). Materials and Methods: Estimating the inactivation kinetics of βPL, BEI, and H2O2 revealed that the tested inactivants could completely and irreversibly inactivate rabies virus within 2, 12, and 4 hours, respectively while maintaining its viral immunogenicity. The potency of βPL, BEI, and H2O2 inactivated vaccines was higher than the World Health Organization acceptance limit and were in the order of 3.75, 4.21, and 3.64 IU/mL, respectively. Monitoring the humoral and cellular immunity elicited post-immunization using Staphylococcus aureus derived hyaluronic acid (HA) and bacillus Calmette-Guérin purified protein derivative (PPD) adjuvanted rabies vaccine candidates were carried out using enzyme-linked immunosorbent assay. Results: Results: demonstrated that both adjuvants could progressively enhance the release of anti-rabies total immunoglobulin G as well as the pro-inflammatory mediators (interferon-gamma and interleukin-5) relative to time. However, a higher immune response was developed in the case of HA adjuvanted rabies vaccine compared to PPD adjuvanted one. The harmful consequences of the tested adjuvants were considered via investigating the histopathological changes in the tissues of the immunized rats using hematoxylin and eosin stain. Lower adverse effects were observed post-vaccination with HA and PPD adjuvanted vaccines compared to that detected following administration of the currently used alum as standard adjuvant. Conclusion Our findings suggested that HA and PPD could serve as a promising platform for the development of newly adjuvanted rabies vaccines with elevated immune enhancing potentials and lower risk of health hazards.

Background: Biomarkers by definition are measurable molecules that mark the evidence of certain pathological processes. Collaboration of various biomarkers influences morbidity of schsitosomiasis in Egypt. Objectives: To identify the biomarkers: CRP, IgE, hemoglobin, ferritin, vitamin D, and platelets in terms of relationship with active and chronic schistosomiasis; demographic data, and their interinfluence. Study design: A cross-sectional study. Methods: Parasitological analysis of stool and urine samples, Indirect Hemagglutination Test, Enzyme linked Immunoassay, Hematology Analyzer, and Statistical Package SPSS (Statistical Package for the Social Sciences) version 25. Results: Out of 400 participants, 25% suffered of schistosomiasis: active S. mansoni infections in 7 cases (1.75%), S. haematobium infections in 6 cases (1.5%), and chronic schistosomiasis infections in 20 cases (5%). Creactive protein (CRP) likewise IgE levels were higher in active S. mansoni and S. haematobium infections when compared with chronic schistosomiasis. IgE levels appeared to affect infection intensity in S. haematobium. Inversely, hemoglobin (Hb) values were low in active schistosomiasis and upgraded in chronic infection (*p<0.05). Ferritin levels varied in active Schistosoma infection and normalized during chronicity. Vitamin D was reduced in active and chronic schistosomiais. Platelet counts were within normal ranges throughout the study groups. Distribution of ferritin, vit D, and platelets was statistically insignificant among Schistosoma infected population. Age affected only hemoglobin, CRP, and IgE biomarkers. CRP and IgE were in direct relationship together and inversely proportional with hemoglobin (*P <0.05). Conclusion: Anemia increased proportionally with biomarkers of inflammatory stress (CRP and IgE) in early infections. Meanwhile, Hb and ferritin (iron stores) improved during chronicity. Hypovitaminosis-D associated the entire course of schistosomiasis while platelet counts were not affected.

PURPOSE: The purpose of this study was to investigate magnetic resonance imaging (MRI) and 3-dimensional transperineal ultrasound (3D-TPUS) features of pelvic floor dysfunction (PFD) in symptomatic women in correlation with digital palpation and to define cut-offs for hiatal dimensions predictive of muscle dysfunction. METHODS: This prospective study included 73 women with symptoms suggesting PFD. 3D-TPUS, MRI, and digital palpation of the levator ani muscle were performed in all patients. Levator hiatal antero-posterior (LHap) diameter and area (LH area) were measured at rest and at maximum muscle contraction. RESULTS: The reduction in LHap diameter and LH area during contraction was significantly less in women with underactive pelvic floor muscle contraction (UpfmC) than in those who had normal pelvic floor muscle contraction by digital palpation (P<0.001). Statistically significant positive correlations (P<0.001) were found between the Modified Oxford Score and 3D-TPUS and MRI regarding the reduction in the LHap diameter (r=0.80 and r=0.82, respectively) and LH area (r=0.60 and r=0.70, respectively). A reduction in LHap of <6.5% on 3D-TPUS and <7.6% on MRI predicted UpfmC with sensitivities of 46.2% and 82.7%, respectively. A reduction in LH area of <3.4% on 3D-TPUS and <3.8% on MRI predicted UpfmC with sensitivities of 75.0% and 88.5%, respectively. MRI was more sensitive in detecting levator avulsion (63.4%) than 3D-TPUS (27.1%). CONCLUSION: MRI and 3D-TPUS had strong positive correlations with findings on palpation, and at certain cut-offs for hiatal dimensions, they can be used as complementary and objective tools to improve the accuracy of diagnosis and management planning of PFD.
Diagnosis ; Female ; Humans ; Magnetic Resonance Imaging ; Muscle Contraction ; Palpation ; Pelvic Floor ; Prospective Studies ; Ultrasonography