3.Erratum: Diagnostic challenges in the assessment of thyroid neoplasms using nuclear features and vascular and capsular invasion: a multi-center interobserver agreement study
Agnes Stephanie HARAHAP ; Mutiah MUTMAINNAH ; Maria Francisca HAM ; Dina KHOIRUNNISA ; Abdillah HASBI ASSADYK ; Husni CANGARA ; Aswiyanti ASRI ; Diah Prabawati RETNANI ; Fairuz QUZWAIN ; Hasrayati AGUSTINA ; Hermawan ISTIADI ; Indri WINDARTI ; Krisna MURTI ; Muhammad TAKBIR ; Ni Made MAHASTUTI ; Nila KURNIASARI ; Nungki ANGGOROWATI ; Pamela ABINENO ; Yulita Pundewi SETYORINI ; Kennichi KAKUDO
Journal of Pathology and Translational Medicine 2025;59(3):201-201
4.Erratum: Diagnostic challenges in the assessment of thyroid neoplasms using nuclear features and vascular and capsular invasion: a multi-center interobserver agreement study
Agnes Stephanie HARAHAP ; Mutiah MUTMAINNAH ; Maria Francisca HAM ; Dina KHOIRUNNISA ; Abdillah HASBI ASSADYK ; Husni CANGARA ; Aswiyanti ASRI ; Diah Prabawati RETNANI ; Fairuz QUZWAIN ; Hasrayati AGUSTINA ; Hermawan ISTIADI ; Indri WINDARTI ; Krisna MURTI ; Muhammad TAKBIR ; Ni Made MAHASTUTI ; Nila KURNIASARI ; Nungki ANGGOROWATI ; Pamela ABINENO ; Yulita Pundewi SETYORINI ; Kennichi KAKUDO
Journal of Pathology and Translational Medicine 2025;59(3):201-201
6.Erratum: Diagnostic challenges in the assessment of thyroid neoplasms using nuclear features and vascular and capsular invasion: a multi-center interobserver agreement study
Agnes Stephanie HARAHAP ; Mutiah MUTMAINNAH ; Maria Francisca HAM ; Dina KHOIRUNNISA ; Abdillah HASBI ASSADYK ; Husni CANGARA ; Aswiyanti ASRI ; Diah Prabawati RETNANI ; Fairuz QUZWAIN ; Hasrayati AGUSTINA ; Hermawan ISTIADI ; Indri WINDARTI ; Krisna MURTI ; Muhammad TAKBIR ; Ni Made MAHASTUTI ; Nila KURNIASARI ; Nungki ANGGOROWATI ; Pamela ABINENO ; Yulita Pundewi SETYORINI ; Kennichi KAKUDO
Journal of Pathology and Translational Medicine 2025;59(3):201-201
8.Do work schedule and work position have an impact on fatigue among geothermal workers during the COVID-19 pandemic? An analysis using structural equation modeling
Caesar Nurhadiono Raharjo ; Suryo Wibowo ; Aria Kekalih ; Amilya Agustina ; Muhammad Ilyas
Acta Medica Philippina 2024;58(Early Access 2024):1-10
Objectives:
This study aimed to examine the impact of work schedule and work position on fatigue levels among employees at a private geothermal firm in Indonesia during the COVID-19 pandemic. The company has modified its work schedule considering the COVID-19 epidemic to ensure a continuous supply of energy and meet the needs of the public.
Methods:
In this cross-sectional study, the dependent variable is fatigue, which is classified as a latent variable. Fatigue is assessed using the Indonesian version of the Swedish Occupational Fatigue Inventory (SOFI). Fatigue is a condition that has five dimensions: lack of energy, physical exertion, physical discomfort, sleepiness, and lack of motivation. The observed variables in this study include work schedule and work position, which serve as independent variables. Using structural equation modeling (SEM), we assessed the impact of the independent variables on each dimension of fatigue. This approach allowed for the analysis of both the measurement and structural models.
Results:
The investigation employed total sampling, involving 132 workers from the company who willingly participated in the study. According to the findings, workers' main fatigue dimension was lack of energy. However, the statistical analysis did not establish a significant influence of work schedule and work position on fatigue.
Conclusion
Based on the findings of the SEM analysis, it is evident that there is no statistically significant correlation between work schedules and job positions with various dimensions of fatigue assessed using the SOFI questionnaire. These dimensions include lack of energy, physical exertion, physical discomfort, sleepiness, and lack of motivation. While this outcome suggests that work schedules and job positions may not directly influence fatigue levels as measured in this study, it underscores the importance of implementing occupational health and safety management systems. Additionally, promoting good work practices such as offering flexible working hours may help address potential fatigue concerns among employees. However, further research is necessary to explore additional variables that could potentially impact fatigue levels in the context of the COVID-19 pandemic and beyond.
Work Schedule
;
Personnel Staffing and Scheduling
9.Effect of tomato and cucumber juice on blood pressure in hypertensive patients: A quasi-experimental study
Agung Sutriyawan ; Ernie Halimatushadyah ; Fibrianti Fibrianti ; Ilham Kamaruddin ; Kurniawan Kurniawan ; Vina Vitniawati ; Ayuda Nia Agustina
Acta Medica Philippina 2024;58(Early Access 2024):1-8
Background:
Hypertension is associated with the improvement of cardiovascular disease and all-cause mortality. A healthy diet based on consuming natural foods can prevent and control hypertension.
Objective:
The aim of this study was to analyze the effectiveness of tomato and cucumber juice in reducing the blood pressure of hypertensive patients.
Methods:
The study used a quasi-experiment pretest-posttest control group design. The target population are people with hypertension Stage 1, people living in urban area - Cibiru Health Centre Work Area. Purposive sampling was used and the sample size was calculated using the average comparison formula with effect size=0.9, α=0.05, β =0.2. Forty-five subjects involved in the study were divided into three groups (15 subjects were given tomato juice, 15 subjects were given cucumber juice, and 15 subjects were given treatment with mineral water (control group)., This research used 100 grams of ripe red tomatoes, 100 grams of fresh cucumber, and 200 ml of water. The data collected were patient characteristics and blood pressure. The ANOVA analysis test and the Bonferroni Post Hoc test were used to analyze the data.
Results:
The results of the study showed a difference in blood pressure reduction in each group. The decrease in systolic blood pressure in the tomato juice group was 7.3+3.1, the cucumber juice group was 4.2+3.3, and the control group was -0.0+2.5 (p=0.0001). The decrease in diastolic blood pressure in the group given tomato juice was 9.2+3.1, the group given cucumber juice was 7.6+3.4, and the control group was 0.4+2.1 (p=0.0001).
Conclusion
There is a difference in blood pressure reduction between the group given tomato juice and the control group, and there is a difference in blood pressure between the group given cucumber juice and the control group.
Blood Pressure
10.Diagnostic challenges in the assessment of thyroid neoplasms using nuclear features and vascular and capsular invasion: a multi-center interobserver agreement study
Agnes Stephanie HARAHAP ; Mutiah MUTMAINNAH ; Maria Francisca HAM ; Dina KHOIRUNNISA ; Abdillah Hasbi ASSADYK ; Husni CANGARA ; Aswiyanti ASRI ; Diah Prabawati RETNANI ; Fairuz QUZWAIN ; Hasrayati AGUSTINA ; Hermawan ISTIADI ; Indri WINDARTI ; Krisna MURTI ; Muhammad TAKBIR ; Ni Made MAHASTUTI ; Nila KURNIASARI ; Nungki ANGGOROWATI ; Pamela ABINENO ; Yulita Pundewi SETYORINI ; Kennichi KAKUDO
Journal of Pathology and Translational Medicine 2024;58(6):299-309
Background:
The diagnosis of thyroid neoplasms necessitates the identification of distinct histological features. Various education/hospital centers located in cities across Indonesia likely result in discordances among pathologists when diagnosing thyroid neoplasms.
Methods:
This study examined the concordance among Indonesian pathologists in assessing nuclear features and capsular and vascular invasion of thyroid tumors. Fifteen pathologists from different centers independently assessed the same 14 digital slides of thyroid tumor specimens. All the specimens were thyroid neoplasms with known BRAFV600E and RAS mutational status, from a single center. We evaluated the pre- and post-training agreement using the Fleiss kappa. The significance of the training was evaluated using a paired T-test.
Results:
Baseline agreement on nuclear features was slight to fair based on a 3-point scoring system (k = 0.14 to 0.28) and poor to fair based on an eight-point system (k = –0.02 to 0.24). Agreements on vascular (κ = 0.35) and capsular invasion (κ = 0.27) were fair, whereas the estimated molecular type showed substantial agreement (κ = 0.74). Following the training, agreement using the eight-point system significantly improved (p = 0.001).
Conclusions
The level of concordance among Indonesian pathologists in diagnosing thyroid neoplasm was relatively poor. Consensus in pathology assessment requires ongoing collaboration and education to refine diagnostic criteria.


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