Child ; Adolescent ; Humans ; Feeding and Eating Disorders/diagnosis*

Child ; Adolescent ; Humans ; Feeding and Eating Disorders/diagnosis*

Eating disorders are often underdiagnosed. Orthorexia nervosa (ON), a new type of eating disorder, is defined as excessive preoccupation with healthy eating, causing significant nutritional deficiencies and social and personal impairments. The ORTO-15 is a 15-item instrument widely used to evaluate orthorexia nervosa. It was developed by Donini et al (2005) in Italian and has been translated and adapted in other languages. In this study, the validity and reliability of the Indonesian version of ORTO-15 were assessed. The Indonesian version of the instrument was then reviewed by experts after translation. The back-translation was assessed for consistency with the original instrument. The instrument was then statistically-tested for validity and reliability on 50 randomly selected subjects. The subjects were balanced in gender and the mean age was 19.4 + 0.8 years. The reliability was tested using Cronbach’s alpha. The validity was tested using Pearson's product-moment correlation and confirmatory factor analyses (CFA). The Pearson product moment verified good validity for the instrument (r = 0.369 – 0.881). CFA analyses confirmed good communalities (extraction > 0.5) and revealed three components construct (cumulative 73.5%). Reliability test confirmed that the instrument had good reliability (Cronbach's alpha = 0.915). The ORTO-15 Indonesian version is a valid and reliable instrument for the assessment of ON.
Reproducibility of Results ; Feeding and Eating Disorders

OBJECTIVES: The epidemic of coronavirus disease 2019 (COVID-19) brought psychological stress to the public, especially to patients. This study aims to investigate the mental health of patients with COVID-19 in Changsha. METHODS: We took cross-section investigation for the mental health of 112 patients with COVID-19 via questionnaires. Mann-Whitney test, Chi-square test, and Fisher's exact test were performed to compare general and clinical data between the slight-ordinary patients and severe patients. Single sample -tests were used to compare the difference between the factor scores of the Symptom Check-List 90 (SCL-90) in COVID-19 patients with the norm of 2015 and factor scores of SCL-90 in patients with the severe acute respiratory syndrome (SARS). RESULTS: The obsessive-compulsive, depression, sleep and eating disorders had the highest frequency among the positive symptoms of SCL-90 in patients with COVID-19 in Changsha. The factor scores of somatization, depression, anxiety, phobia anxiety, sleep and eating disorders in patients with COVID-19 were higher than those of the norm (≤0.001 or <0.05). Slight-ordinary patients with COVID-19 in Changsha showed lower factor scores of somatization, depression, anxiety, and hostility compared with the patients with SARS (<0.001 or <0.05). There was no difference in factor scores of SCL-90 between the patients with severe COVID-19 and those with SARS(>0.05). CONCLUSIONS The levels of somatization, depression, anxiety, phobia anxiety, sleep and eating disorders in patients with COVID-19 in Changsha are higher than those of the norm. However, the mental health of slight-ordinary patients with COVID-19 is better than that of patients with SARS. It needs to provide targeting psychological interventions depending on the severity of patients.
Anxiety ; Betacoronavirus ; China ; Coronavirus Infections ; psychology ; Depression ; Feeding and Eating Disorders ; Health Status ; Humans ; Mental Health ; Pandemics ; Pneumonia, Viral ; psychology ; Sleep Wake Disorders ; Surveys and Questionnaires

Anorexia nervosa (AN) affects 2.9 million people, many of whom experience bone loss and increased fracture risk. In this article, we review data on the underlying pathophysiology of AN-related osteoporosis and possible approaches to disease management. Available research suggests that low body weight and decreased gonadal function are the strongest predictors of bone loss and fractures in patients with AN. Additionally, other metabolic disturbances have been linked to bone loss, including growth hormone resistance, low leptin concentrations, and hypercortisolemia, but those correlations are less consistent and lack evidence of causality. In terms of treatment of AN-related bone disease, weight gain has the most robust impact on bone mineral density (BMD). Restoration of gonadal function seems to augment this effect and may independently improve BMD. Bisphosphonates, insulin-like growth factor 1 supplementation, and teriparatide may also be reasonable considerations, however need long-term efficacy and safety data.
Anorexia Nervosa ; Anorexia ; Body Weight ; Bone Density ; Bone Diseases ; Diphosphonates ; Disease Management ; Feeding and Eating Disorders ; Gonads ; Growth Hormone ; Humans ; Leptin ; Osteoporosis ; Teriparatide ; Weight Gain

Eating disorders have especially devastating consequences for patients with diabetes. Even subclinical eating disorders can interfere with glycemic control and result in complications of diabetes mellitus. But, eating disorders of diabetic patients are often undetected and untreated. Therefore, diabetes educators must play a critical role in the detection, support, referral, and treatment of diabetic patients with eating disorders.
Diabetes Complications ; Diabetes Mellitus ; Eating* ; Feeding and Eating Disorders ; Humans ; Referral and Consultation

As the physical abnormalities seen in eating disorders seem to be largely secondary to these patients' disturbed eating habits and their compromised nutritional state, most physical abnormalities associated with eating disorders are reversed by restoring healthy eating habits and sound nutrition. However, some medical consequences of eating disorders are irreversible or have later repercussions on health, especially those affecting the skeleton, the reproductive system, and the brain. Early medical intervention and psychiatric treatment are particularly important for those with or at risk of severe emaciation. Eating disorders are common among adolescent girls and young women and are associated with potentially serious medical complications, yet they often go undetected and untreated. All patients with eating disorders should be evaluated and treated for medical complications of the disease at the same time that psychotherapy and nutritional counseling are undertaken.
Adolescent ; Anorexia Nervosa ; Binge-Eating Disorder ; Brain ; Bulimia Nervosa ; Counseling ; Early Medical Intervention ; Eating ; Emaciation ; Feeding and Eating Disorders ; Female ; Humans ; Psychotherapy ; Skeleton

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive hereditary disease and is a congenital metabolic disorder of neurotransmitter biosynthesis. It is mainly manifested as hypotonia, oculogyric crisis, autonomic dysfunction, and developmental delay. This article reports a boy manifested as delayed motor development, hypotonia, and oculogyric crisis. Gene screening for metabolic disorders revealed new compound heterozygous mutations, c.1063dupA (p.I355fs) and c.250A>C (p.S84R), in the exon of DDC gene. The boy had a significant increase in 3-O-methyldopa as measured by dried blood spot. Therefore, he was diagnosed with AADC deficiency. After treatment with the dopamine receptor agonist pramipexole dihydrochloride, the catechol-O-methyltransferase inhibitor entacapone, and vitamin B6, the boy showed mild improvements in hypotonia, blepharoptosis, and oculogyric crisis. Clinical physicians should enhance their ability for identifying AADC deficiency, so as to facilitate early diagnosis and treatment of this disorder. Genetic counseling for birth health and prenatal diagnosis should be performed for parents in need.
Amino Acid Metabolism, Inborn Errors ; complications ; Aromatic-L-Amino-Acid Decarboxylases ; deficiency ; Developmental Disabilities ; etiology ; Feeding and Eating Disorders ; etiology ; Humans ; Infant ; Male ; Nystagmus, Pathologic ; etiology

OBJECTIVES: The current study aimed to investigate individuals with night eating syndrome tendency in 115 female undergraduate sample based on night eating syndrome criteria, and analyze its association between mood, sleep, and alcohol use. METHODS: Subjects were divided into high and low tendency group of night eating syndrome based on the night eating questionnaire. All participants completed the Hospital Anxiety and Depression Scale, Insomnia Severity Index, Munich Chronotype Questionnaire, and Alcohol-Use Disorders Identification Test. Data was collected at two time points which were 3 months apart. All analyses were conducted using repeated measure ANOVA. RESULTS: Results indicated a significant difference between night eating syndrome tendency groups for anxiety and depression [F(1,113)=12.35, p=0.001 and F(1,113)=9.59, p=0.002, respectively]. Depression also had a significant time effect [F(1,113)=11.15, p=0.001]. Additionally, the high night eating syndrome tendency group had higher levels of insomnia severity [F(1,113)=24.34, p<0.001], eveningness [F(1,113)=15.09, p<0.001], and alcohol use [F(1,113)=6.73, p=0.011], and lower sleep efficiency [F(1,113)=6.30, p=0.014] compared to the low night eating syndrome tendency group. CONCLUSIONS: The high night eating syndrome tendency group had higher negative mood, sleep disturbance, and alcohol use compared to the low night eating syndrome tendency group. In summary, intervention for night eating syndrome may be important to consider in undergraduate students.
Alcohol Drinking ; Anxiety ; Circadian Rhythm ; Depression ; Eating* ; Feeding and Eating Disorders ; Female* ; Humans ; Sleep Initiation and Maintenance Disorders

PURPOSE: The aim of this study was to develop a Korean version of Night Eating Questionnaire (KNEQ) and test its psychometric properties and evaluate items according to item response theory. METHODS: The 14-item NEQ as a measure of severity of the night eating syndrome was translated into Korean, and then this KNEQ was evaluated. A total of 1171 participants aged 20 to 50 completed the KNEQ on the Internet. To test reliability and validity, Cronbach's alpha, correlation, simple regression, and factor analysis were used. Each item was analyzed according to Rasch-Andrich rating scale model and item difficulty, discrimination, infit/outfit, and point measure correlation were evaluated. RESULTS: Construct validity was evident. Cronbach's alpha was .78. The items of evening hyperphagia and nocturnal ingestion showed high ability in discriminating people with night eating syndrome, while items of morning anorexia and mood/sleep provided relatively little information. The results of item analysis showed that item2 and item7 needed to be revised to improve the reliability of KNEQ. CONCLUSION: KNEQ is an appropriate instrument to measure severity of night eating syndrome with good validity and reliability. However, further studies are needed to find cut-off scores to screen persons with night eating syndrome.
Adult ; Anorexia/etiology ; Factor Analysis, Statistical ; Feeding and Eating Disorders/*psychology ; Humans ; Internet ; Middle Aged ; *Program Evaluation ; *Psychometrics ; Republic of Korea ; Self Report ; Surveys and Questionnaires ; Translating ; Young Adult