1.Biofilm formation and antibiotic resistance of urinary catheter associated bacteria from hospitalized patients, Bangladesh
Malaysian Journal of Microbiology 2021;17(6):635-645
		                        		
		                        			Aims:
		                        			Biofilm formation of bacteria inside the surface of urinary catheters triggers severe urinary tract infections (UTIs). This study aims to determine the biofilm forming capacity of bacteria isolated from urinary catheters of patients diagnosed with UTIs as well as comparison of antibiotic sensitivity patterns between biofilm and non-biofilm forming isolates.
		                        		
		                        			Methodology and results:
		                        			A total of 40 urinary catheters were collected from 96 h catheterized patients. The isolated uropathogenic bacteria were identified and examined for biofilm formation using the microtiter plate method. Later, the isolates were subjected to antimicrobial susceptibility towards 12 antibiotics that commonly used for treating UTIs using the disk diffusion method. All the catheters were found colonized with two to five different bacterial species individually. Out of the 131 isolates from 40 catheters, Pseudomonas aeruginosa (38/131, 29%) was the predominant isolated bacteria followed by Escherichia coli (31/131, 24%), Proteus vulgaris (24/131, 18%), Klebsiella pneumoniae (21/131, 16%) and Staphylococcus aureus (17/131, 13%). Among these, the highest biofilm forming capacity was observed in P. aeruginosa (26%), followed by P. vulgaris (16%) and K. pneumoniae (13%). Regarding antibiotic resistance, biofilm forming bacteria showed resistance to multiple drugs except for carbapenems. Moreover, biofilm formers exhibited higher resistance than non-biofilm formers against antibiotics such as trimethoprim/sulfamethoxazole (100% vs 82%), amoxicillin-clavulanic acid (81% vs 55%), cefixime (85% vs 55%), ceftriaxone (81% vs 45%), cefalexin (93% vs 55%), amikacin (70% vs 45%), ampicillin (89% vs 73%), ciprofloxacin (70% vs. 36%) and ceftriaxone (81 vs 45%), (p-value<0.05). 
		                        		
		                        			Conclusion, significance and impact of study
		                        			Most of the isolated uropathogenic bacteria from catheters were biofilm formers and multiple antibiotic resistant. Appropriate selection of antibiotics, meticulous hygiene practices in hospital settings and limiting the duration of catheterization can reduce biofilm formation and the emergence of antibiotic resistance.
		                        		
		                        		
		                        		
		                        			Biofilms
		                        			;
		                        		
		                        			 Urinary Catheters
		                        			;
		                        		
		                        			 Urinary Tract Infections
		                        			
		                        		
		                        	
2.Feasibility of Robot-Assisted Gait Training with an End-Effector Type Device for Various Neurologic Disorders
Soojin CHOI ; Seong Woo KIM ; Ha Ra JEON ; June Sung LEE ; Dong Yeong KIM ; Jang Woo LEE
Brain & Neurorehabilitation 2020;13(1):6-
		                        		
		                        			
		                        			Robots are being used to assist the recovery of walking ability for patients with neurologic disorders. This study aimed to evaluate the feasibility and functional improvement of training with robot-assisted gait training (RAGT) using the Morning Walk®, an end-effector type robot using footplates and saddle seat support. A total of 189 individuals (65.1% men, 34.9% women; mean age, 53.2 years; age range: 5–87 years) with brain lesions, spinal cord injuries, Parkinson's disease, peripheral neuropathies, and pediatric patients were involved in this retrospectively registered clinical trial. Each participant performed 30 minutes of RAGT, five times a week, for a total of 24 sessions. Failure was defined as an inability to complete all 24 sessions, and the reasons for discontinuation were analyzed. Parameters of Medical Research Council scales and Functional Ambulation Categories were analyzed before and after RAGT training. Among the 189 patients, 22 (11.6%) failed to complete the RAGT. The reasons included decreased cooperation, musculoskeletal pain, saddle seat discomfort, excessive body-weight support, joint spasticity or restricted joint motion, urinary incontinence from an indwelling urinary catheter, and fatigue. Comparison between the pre- and post-training motor and ambulatory functions showed significant improvement. The result of the study indicates that the Morning Walk® is feasible and safe and useful for functional improvement in patients with various neurologic disordersTRIAL REGISTRATION: Clinical Research Information Service Identifier: KCT0003627
		                        		
		                        		
		                        		
		                        			Brain
		                        			;
		                        		
		                        			Fatigue
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Gait
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Information Services
		                        			;
		                        		
		                        			Joints
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Muscle Spasticity
		                        			;
		                        		
		                        			Musculoskeletal Pain
		                        			;
		                        		
		                        			Nervous System Diseases
		                        			;
		                        		
		                        			Parkinson Disease
		                        			;
		                        		
		                        			Peripheral Nervous System Diseases
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Spinal Cord Injuries
		                        			;
		                        		
		                        			Urinary Catheters
		                        			;
		                        		
		                        			Urinary Incontinence
		                        			;
		                        		
		                        			Walking
		                        			;
		                        		
		                        			Weights and Measures
		                        			
		                        		
		                        	
3.Implementation of Enhanced Recovery after Surgery (ERAS) Program in Perioperative Management of Gastric Cancer Surgery: a Nationwide Survey in Korea
Journal of Gastric Cancer 2019;19(1):72-82
		                        		
		                        			
		                        			PURPOSE: Despite its clinical benefits, enhanced recovery after surgery (ERAS) is less widely implemented for gastric cancer surgery. This nationwide survey investigated the current status of the implementation of ERAS in perioperative care for gastric cancer surgery in South Korea. MATERIALS AND METHODS: This survey enrolled 89 gastric surgeons from 52 institutions in South Korea. The questionnaire consisted of 24 questions about the implementation of the ERAS protocols in the management of gastric cancer surgery. The survey was carried out using an electronic form sent via email. RESULTS: Of the 89 gastric surgeons, 58 (65.2%) answered that they have knowledge of the concept and details of ERAS, 45 (50.6%) of whom were currently applying ERAS for their patients. Of the ERAS protocols, preoperative education (91.0%), avoidance of preoperative fasting (68.5%), maintenance of intraoperative normothermia (79.8%), thromboprophylaxis (96.5%), early active ambulation (64.4%), and early removal of urinary catheter (68.5%) were relatively well adopted in perioperative care. However, other practices, such as avoidance of preoperative bowel preparation (41.6%), provision of preoperative carbohydrate-rich drink (10.1%), avoidance of routine abdominal drainage (31.4%), epidural anesthesia (15.9%), single-dose prophylactic antibiotics (19.3%), postoperative high oxygen therapy (36.8%), early postoperative diet (14.6%), restricted intravenous fluid administration (53.9%), and application of discharge criteria (57.3%) were not very well adopted for patients. CONCLUSIONS: Perioperative management of gastric cancer surgery is largely heterogeneous among gastric surgeons in South Korea. Standard perioperative care based on scientific evidence needs to be established to improve the quality of surgical care and patient outcomes.
		                        		
		                        		
		                        		
		                        			Anesthesia, Epidural
		                        			;
		                        		
		                        			Anti-Bacterial Agents
		                        			;
		                        		
		                        			Diet
		                        			;
		                        		
		                        			Drainage
		                        			;
		                        		
		                        			Education
		                        			;
		                        		
		                        			Electronic Mail
		                        			;
		                        		
		                        			Fasting
		                        			;
		                        		
		                        			Gastrectomy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Korea
		                        			;
		                        		
		                        			Oxygen
		                        			;
		                        		
		                        			Perioperative Care
		                        			;
		                        		
		                        			Stomach Neoplasms
		                        			;
		                        		
		                        			Surgeons
		                        			;
		                        		
		                        			Urinary Catheters
		                        			;
		                        		
		                        			Walking
		                        			
		                        		
		                        	
4.Foreign Body Removal in Children Using Foley Catheter or Magnet Tube from Gastrointestinal Tract
Jae Young CHOE ; Byung Ho CHOE
Pediatric Gastroenterology, Hepatology & Nutrition 2019;22(2):132-141
		                        		
		                        			
		                        			Foreign body (FB) ingestion of children is a common pediatric emergency requiring medical attention. Pediatric emergency physicians and gastroenterologists often encounter nervous and distressed situations, because of children presenting with this condition in the common clinical practice. When determining the appropriate timing and indications for intervention, physicians should consider multiple patient- and FB-related factors. The utilization of a flexible endoscopy is considered safe and effective to use in these cases, with a high success rate, for the effective extraction of FBs from the gastrointestinal tract of a child. Additionally, a Foley catheter and a magnet-attached Levin tube have been used for decades in the case of FB removal. Although their use has decreased significantly in recent times, these instruments continue to be used for several indications. Using a Foley catheter for this purpose does not require special training and does not necessarily require sedation of the patient or fluoroscopy, which serve as advantages of utilizing this method for foreign object retrieval. An ingested magnet or iron-containing FB can be retrieved using a magnet-attached tube, and can be effective to retrieve an object from any section of the upper gastrointestinal tract that can be reached. Simple and inexpensive devices such as Foley catheters and magnet-attached tubes can be used in emergencies such as with the esophageal impaction of disk batteries if endoscopy cannot be performed immediately (e.g., in rural areas and/or in patients presenting at midnight in a facility, especially in those without access to endoscopes or emergency services, or in any situation that warrants urgent removal of a foreign object).
		                        		
		                        		
		                        		
		                        			Catheters
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Eating
		                        			;
		                        		
		                        			Emergencies
		                        			;
		                        		
		                        			Endoscopes
		                        			;
		                        		
		                        			Endoscopy
		                        			;
		                        		
		                        			Esophagus
		                        			;
		                        		
		                        			Fluoroscopy
		                        			;
		                        		
		                        			Foreign Bodies
		                        			;
		                        		
		                        			Gastrointestinal Tract
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Methods
		                        			;
		                        		
		                        			Upper Gastrointestinal Tract
		                        			;
		                        		
		                        			Urinary Catheterization
		                        			
		                        		
		                        	
5.Whole body ultrasound in the operating room and intensive care unit
André DENAULT ; David CANTY ; Milène AZZAM ; Alexander AMIR ; Caroline E GEBHARD
Korean Journal of Anesthesiology 2019;72(5):413-428
		                        		
		                        			
		                        			Whole body ultrasound can be used to improve the speed and accuracy of evaluation of an increasing number of organ systems in the critically ill. Cardiac and abdominal ultrasound can be used to identify the mechanisms and etiology of hemodynamic instability. In hypoxemia or hypercarbia, lung ultrasound can rapidly identify the etiology of the condition with an accuracy that is equivalent to that of computed tomography. For encephalopathy, ocular ultrasound and transcranial Doppler can identify elevated intracranial pressure and midline shift. Renal and bladder ultrasound can identify the mechanisms and etiology of renal failure. Ultrasound can also improve the accuracy and safety of percutaneous procedures and should be currently used routinely for central vein catheterization and percutaneous tracheostomy.
		                        		
		                        		
		                        		
		                        			Anoxia
		                        			;
		                        		
		                        			Brain Diseases
		                        			;
		                        		
		                        			Catheterization
		                        			;
		                        		
		                        			Catheters
		                        			;
		                        		
		                        			Critical Care
		                        			;
		                        		
		                        			Critical Illness
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Intensive Care Units
		                        			;
		                        		
		                        			Intracranial Hypertension
		                        			;
		                        		
		                        			Lung
		                        			;
		                        		
		                        			Operating Rooms
		                        			;
		                        		
		                        			Renal Insufficiency
		                        			;
		                        		
		                        			Tracheostomy
		                        			;
		                        		
		                        			Ultrasonography
		                        			;
		                        		
		                        			Urinary Bladder
		                        			;
		                        		
		                        			Veins
		                        			
		                        		
		                        	
6.Recent Updates in Urinary Catheter Products for the Neurogenic Bladder Patients with Spinal Cord Injury
Seong Jin JEONG ; Seung June OH
Korean Journal of Neurotrauma 2019;15(2):77-87
		                        		
		                        			
		                        			Clean intermittent catheterization (CIC) is one of the core elements of neurogenic bladder management in the patients with spinal cord injury and is effective and safe to maintain low intra-bladder pressure and achieve urinary continence. Until now, the most notable development in urinary catheter products for CIC is the introduction of hydrophilic coating. Fortunately, in Korea, the national medical insurance has recently covered the cost for urinary catheters in this patient group. The purpose of this review is to summarize the history of CIC and the recent development of urinary catheter products. From our review, we would like to suggest a way of thinking that is the way forward for the future to improve the implementation of CIC with minimal morbidity.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Insurance
		                        			;
		                        		
		                        			Intermittent Urethral Catheterization
		                        			;
		                        		
		                        			Korea
		                        			;
		                        		
		                        			Spinal Cord Injuries
		                        			;
		                        		
		                        			Spinal Cord
		                        			;
		                        		
		                        			Thinking
		                        			;
		                        		
		                        			Urinary Bladder, Neurogenic
		                        			;
		                        		
		                        			Urinary Catheters
		                        			
		                        		
		                        	
7.Chlorhexidine: a hidden life-threatening allergen
Mara FERNANDES ; Tatiana LOURENÇO ; Anabela LOPES ; Amélia SPÍNOLA SANTOS ; Maria Conceição PEREIRA SANTOS ; Manuel PEREIRA BARBOSA
Asia Pacific Allergy 2019;9(4):e29-
		                        		
		                        			
		                        			Chlorhexidine is a commonly used antiseptic and disinfectant in the health-care setting. Anaphylaxis to chlorhexidine is a rare but potentially life-threatening complication. Epidemiologic data suggest that the cases of chlorhexidine allergy appears to be increasing. In this article we report a life-threatening anaphylactic shock with cardiorespiratory arrest, during urethral catheterization due to chlorhexidine. The authors also performed a literature review of PubMed library of anaphylactic cases reports due to this antiseptic between 2014 and 2018, demonstrating the increase in the number of cases occurring worldwide and the importance of detailed anamnesis and appropriate diagnostic workup of allergic reactions to disinfectants.
		                        		
		                        		
		                        		
		                        			Anaphylaxis
		                        			;
		                        		
		                        			Chlorhexidine
		                        			;
		                        		
		                        			Disinfectants
		                        			;
		                        		
		                        			Hypersensitivity
		                        			;
		                        		
		                        			Urinary Catheterization
		                        			;
		                        		
		                        			Urinary Catheters
		                        			
		                        		
		                        	
8.Linguistic Validation of the Intermittent Self-catheterization Questionnaire for Patients With Neurogenic Bladder Who Perform Intermittent Catheterization for Voiding Dysfunction
Soon Ho KANG ; Seung June OH ; Seong Jin JEONG ; Sung Yong CHO
International Neurourology Journal 2019;23(1):75-85
		                        		
		                        			
		                        			PURPOSE: In recent years, the importance of patient satisfaction and quality of life—referred to as patient-related outcomes— has been emphasized, in addition to the evaluation of symptoms and severity through questionnaires. However, the questionnaires that can be applied to Korean patients with neurogenic bladder are limited. Therefore, the current study linguistically validated the Intermittent Self-Catheterization Questionnaire (ISC-Q) as an instrument to evaluate the quality of life of Korean patients with neurogenic bladder who regularly perform clean intermittent catheterization (CIC). METHODS: The validation process included permission for translation, forward translations, reconciliation, backward translation, cognitive debriefing, and proofreading. Two bilingual translators independently translated the original version of the ISC-Q into Korean and then combined the initial translations. A third bilingual translator performed a backward translation of the reconciled version into English. Five Korean-speaking patients with neurogenic bladder carried out the cognitive debriefing. RESULTS: During the forward translation process, the 24 questions of the ISC-Q were translated into 2 Korean versions. The terms used in each version were adjusted from the original version to use more conceptually equivalent expressions in Korean. During the backward translation process, several changes were involving substitutions of meaning. In the cognitive debriefing process, 5 patients were asked to complete the questionnaire. All patients agreed that the questionnaire explained their situation well. CONCLUSIONS: This study presents a successful linguistic validation of the Korean version of the ISC-Q, which could be a useful tool for evaluating treatment satisfaction in patients with neurogenic bladder performing CIC regularly.
		                        		
		                        		
		                        		
		                        			Catheterization
		                        			;
		                        		
		                        			Catheters
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intermittent Urethral Catheterization
		                        			;
		                        		
		                        			Linguistics
		                        			;
		                        		
		                        			Patient Satisfaction
		                        			;
		                        		
		                        			Quality of Life
		                        			;
		                        		
		                        			Translations
		                        			;
		                        		
		                        			Urinary Bladder, Neurogenic
		                        			;
		                        		
		                        			Urination
		                        			
		                        		
		                        	
9.Feasibility of Self-administered Neuromodulation for Neurogenic Bladder in Spinal Cord Injury
Argyrios STAMPAS ; Rose KHAVARI ; Joel E FRONTERA ; Suzanne L GROAH
International Neurourology Journal 2019;23(3):249-256
		                        		
		                        			
		                        			PURPOSE: To determine if self-administered transcutaneous tibial nerve stimulation (TTNS) is a feasible treatment option for neurogenic bladder among people with spinal cord injury (SCI) who utilize intermittent catheterization for bladder management. METHODS: Four-week observational trial in chronic SCI subjects performing intermittent catheterization with incontinence episodes using TTNS at home daily for 30 minutes. Those using anticholinergic bladder medications were given a weaning schedule to begin at week 2. Primary outcomes were compliance and satisfaction. Secondary outcomes included change in bladder medications, efficacy based on bladder diary, adverse events, and incontinence quality of life (I-QoL) survey.
		                        		
		                        		
		                        		
		                        			Appointments and Schedules
		                        			;
		                        		
		                        			Catheterization
		                        			;
		                        		
		                        			Catheters
		                        			;
		                        		
		                        			Compliance
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mouth
		                        			;
		                        		
		                        			Quality of Life
		                        			;
		                        		
		                        			Sleep Stages
		                        			;
		                        		
		                        			Spinal Cord Injuries
		                        			;
		                        		
		                        			Spinal Cord
		                        			;
		                        		
		                        			Tibial Nerve
		                        			;
		                        		
		                        			Transcutaneous Electric Nerve Stimulation
		                        			;
		                        		
		                        			Urinary Bladder
		                        			;
		                        		
		                        			Urinary Bladder, Neurogenic
		                        			;
		                        		
		                        			Urodynamics
		                        			;
		                        		
		                        			Weaning
		                        			
		                        		
		                        	
10.The Effectiveness of Cystography-Measured Bladder Neck Elevation at Predicting the Return of Continence After Robot-Assisted Radical Prostatectomy
Jung Sik HUH ; Young Joo KIM ; Sung Dae KIM ; Kyung Kgi PARK
International Neurourology Journal 2019;23(3):234-239
		                        		
		                        			
		                        			PURPOSE: To analyze the clinical parameters correlated with early recovery of urinary continence after radical prostatectomy, with a focus on urethral mobility during pelvic contraction at catheter removal. METHODS: We prospectively analyzed 67 patients who underwent prostatectomy for prostate cancer at Jeju National University Hospital from January 2015 to June 2018. At the time of catheter removal, a cystography was performed in 67 men (median age, 65 years; range, 55–76 years) who had undergone robot-assisted laparoscopic prostatectomy. The vertical length of bladder neck movement between relaxing and contracting the pelvic muscles was measured. The correlation between the rate of continence recovery and the length of urethral movement was also assessed. All participants were divided into 2 groups according to the length of bladder neck elevation. Group 1 had ≥0.6 cm of elevation, while group 2 demonstrated <0.6 cm of elevation. RESULTS: A reverse correlation existed between the length of urethral movement and the recovery rate of urinary continence (r=–0.488, P<0.001). The optimal cutoff value for length of urethral movement was found to be 0.6 cm among patients (area under the curve, 0.703). A statistically significant difference was observed between group 1 (length≥0.6 cm) and group 2 (<0.6 cm) (P<0.05). Multivariate regression analysis showed that urethral movement predicted the postoperative urinary incontinence. CONCLUSIONS: The extent of bladder neck elevation after robot-assisted laparoscopic prostatectomy, which can be easily evaluated using cystography, may be a good predictor of the recovery of urinary continence.
		                        		
		                        		
		                        		
		                        			Catheters
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Muscles
		                        			;
		                        		
		                        			Neck
		                        			;
		                        		
		                        			Prospective Studies
		                        			;
		                        		
		                        			Prostatectomy
		                        			;
		                        		
		                        			Prostatic Neoplasms
		                        			;
		                        		
		                        			Urinary Bladder
		                        			;
		                        		
		                        			Urinary Incontinence
		                        			
		                        		
		                        	
            

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