2.Ileo-Ileal Intussusception with Meckel Diverticulum in a Filipino adolescent
John Nicholas Pantoja ; Manuelito Madrid
Philippine Journal of Pathology 2023;8(2):53-56
		                        		
		                        			
		                        			Intussusception refers to the invagination (telescoping) of a part of the intestine into itself. Intussusception occurs primarily in infants and toddlers.1 The peak incidence is between 4 and 36 months of age, and it is the most common cause of intestinal obstruction in this age group. 2 Approximately 1 percent of cases are in infants younger than three months, 30 percent between 3 and 12 months, 20 percent between one and two years, 25 percent between two and three years, and 10 percent between three and four years.3 Although intussusception is most common in infants and young children, it is important to consider this diagnosis in children outside this age range. Approximately 10 percent of cases are in children over five years, and 3 to 4 percent in those over 10 years.3,4 We share here images from an actual case of a 15-year-old Filipino male with an ileo-ileal intussusception that is beyond the typical age range, with an incidental finding of an intraluminal mass that was histomorphologically diagnosed as Meckel’s diverticulum (MD). The diagnosis of intussusception is relatively rare in the patient’s age and the diagnosis of MD in the presence of intussusception is sparsely reported in the Philippines.
Intussusception refers to the invagination (telescoping) of a part of the intestine into itself. Intussusception occurs primarily in infants and toddlers.1 The peak incidence is between 4 and 36 months of age, and it is the most common cause of intestinal obstruction in this age group. 2 Approximately 1 percent of cases are in infants younger than three months, 30 percent between 3 and 12 months, 20 percent between one and two years, 25 percent between two and three years, and 10 percent between three and four years.3 Although intussusception is most common in infants and young children, it is important to consider this diagnosis in children outside this age range. Approximately 10 percent of cases are in children over five years, and 3 to 4 percent in those over 10 years.3,4 We share here images from an actual case of a 15-year-old Filipino male with an ileo-ileal intussusception that is beyond the typical age range, with an incidental finding of an intraluminal mass that was histomorphologically diagnosed as Meckel’s diverticulum (MD). The diagnosis of intussusception is relatively rare in the patient’s age and the diagnosis of MD in the presence of intussusception is sparsely reported in the Philippines.
		                        		
		                        		
		                        		
		                        			Meckel Diverticulum
		                        			;
		                        		
		                        			 Strabismus
		                        			;
		                        		
		                        			 Adolescent 
		                        			
		                        		
		                        	
5.A novel onlay urethroplasty for hypospadias with mild chordee after degloving: modified for complete removal of scar tissue underlying the urethral plate and for long-term outcomes.
Li-Qu HUANG ; Zheng GE ; Li-Xia WANG ; Xiao-Yu LI ; Yong-Ji DENG ; Yun-Fei GUO ; Geng MA
Asian Journal of Andrology 2022;24(6):639-642
		                        		
		                        			
		                        			Urethral plate (UP)-preserving urethroplasty is simple and has few complications, but it may affect the development of penis in the long term and lead to recurrent chordee. In this study, we used obliquely cut UP to repair hypospadias with mild chordee after degloving (15°-30°) and compared the results with onlay urethroplasty to explore its rationality and feasibility. Between April 2018 and October 2020, 108 hypospadias patients underwent onlay urethroplasty or modified onlay urethroplasty. Clinical data were prospectively collected, and medium-term outcomes were assessed at follow-up. The complications were compared between the two groups. Forty-four patients underwent the modified onlay procedure (Group I), with follow-up time (mean ± standard deviation [s.d.]) of 23.2 ± 4.5 (range: 17-31) months. Sixty-four patients underwent a standard onlay procedure (Group II), with follow-up time (mean ± s.d.) of 39.7 ± 3.9 (range: 32-46) months. There was no difference in age at surgery. The urethral defect length and operative time were longer in Group I. Six cases of fistula and one case each of stricture and diverticulum were reported in Group I. In Group II, 11 cases of fistula and one case each of stricture and diverticulum were reported. The complication rates were 18.2% and 20.3% in Group I and Group II, respectively (P > 0.05). These medium-term follow-up results demonstrate that the modified onlay procedure (oblique cut UP urethroplasty) is a safe and feasible technique for hypospadias with mild chordee after degloving. Compared with standard onlay urethroplasty, this modified procedure is conducive to the complete removal of scar tissue underlying the UP without increasing the risk of surgical complications.
		                        		
		                        		
		                        		
		                        			Male
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Hypospadias/surgery*
		                        			;
		                        		
		                        			Cicatrix/surgery*
		                        			;
		                        		
		                        			Constriction, Pathologic/surgery*
		                        			;
		                        		
		                        			Urethra/surgery*
		                        			;
		                        		
		                        			Diverticulum
		                        			;
		                        		
		                        			Urologic Surgical Procedures, Male/methods*
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
6.Clinical analysis of 554 patients with colorectal diverticulosis.
Jun Ling ZHANG ; Gui Gen TENG ; Tao WU ; Guo Wei CHEN ; Peng Yuan WANG ; Yong JIANG ; Ying Chao WU ; Lie SUN ; Tao LIU ; Shuai ZUO ; Yi Sheng PAN ; Xin WANG
Chinese Journal of Gastrointestinal Surgery 2021;24(11):1008-1014
		                        		
		                        			
		                        			Objective: Most patients with asymptomatic colorectal diverticulosis are easily overlooked. However, some of diverticulosis become diverticulitis, bleeding and even perforation, which cause extensive harm to patients. The purpose of this study is to analyze the incidence, clinical features, diagnosis and treatment of colorectal diverticulosis in order to improve the clinical understanding of diverticulosis and its related complications. Methods: A descriptive cohort study was carried out. Clinical data of 554 patients with colorectal diverticulosis confirmed by CT, colonoscopy, digestive tract radiography or operation in Peking University First Hospital from January 2009 to June 2019 were retrospectively analyzed. Patients with malignant tumors, autoimmune diseases, long term use of immunosuppressive drugs, chronic liver diseases and renal diseases, and mental disorders were excluded. The analysis parameters included gender, onset age, clinical symptoms, location of diverticulitis, treatment and prognosis. According to the criteria established by the World Society of Emergency Surgery (WSES), acute diverticulitis was divided into 5 stages based on the extension of the infectious process. Stage 0 was simple diverticulitis and stage 1-4 was complicated diverticulitis. Results: Among the 554 patients with colorectal diverticulosis, 358 (64.6%) were males, the median onset age was 63 years; 191 patients (34.5%) had various digestive symptoms, of whom 113 (20.4%) had chronic constipation and abdominal distension, 78 (14.1%) had chronic diarrhea and abdominal pain; the other 363 patients had no obvious abdominal symptoms. Four hundred and six patients were found by colonoscopy and 465 patients were found by CT. Twenty-five patients were diagnosed by lower gastrointestinal tract radiography and 3 were confirmed during operation. There were 339 patients with multiple diverticula (61.2%) and 215 patients with single diverticulum (38.8%). 76.5% (424/554) of diverticula were located in colon, 37.0% (205/554) in ascending colon, 21.3% (118/554) in multiple sites, and 2.2% (12/554) in rectum. The median diameter of diverticulum was 7 mm, and 78 cases (14.1%) was ≥30 mm. Forty-nine patients (8.8%) developed acute diverticulitis, including 13 patients with simple diverticulitis and 36 patients with complicated diverticulitis. Among 36 patients with complicated diverticulitis, 29 (80.6%) were males, 27 (75.0%) had recurrent abdominal pain and fever before onset; diverticula of 25 cases were located in sigmoid colon; 11 cases in ascending colon. Nine cases developed sigmoid colon perforation and 8 cases developed vesicocolonic fistula, and these 17 patients underwent surgical treatment. The other 19 cases with complicated diverticulitis developed gastrointestinal bleeding, of whom 18 cases were male, 11 cases were located in ascending colon; 13 cases were healed after conservative treatment, 4 cases received endoscopic hemostatic intervention, and 2 cases underwent surgery. Conclusions: Colorectal diverticulosis is more common in male patients, and CT and colonoscopy are main diagnostic methods. The symptoms of complicated colonic diverticulitis are related to the location of diverticulum. In addition to symptomatic treatment, surgical procedures are the most important treatments.
		                        		
		                        		
		                        		
		                        			Cohort Studies
		                        			;
		                        		
		                        			Colorectal Neoplasms
		                        			;
		                        		
		                        			Diverticulitis, Colonic
		                        			;
		                        		
		                        			Diverticulum
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Retrospective Studies
		                        			
		                        		
		                        	
7.Value of capsule endoscopy in children with small intestinal diseases with hematochezia as the chief complaint.
Jie WU ; Ai-Juan XUE ; Zi-Fei TANG ; Yu-Huan WANG ; Ying HUANG
Chinese Journal of Contemporary Pediatrics 2020;22(9):1007-1010
		                        		
		                        			OBJECTIVE:
		                        			To evaluate the value of capsule endoscopy in children with small intestinal diseases with hematochezia as the chief complaint.
		                        		
		                        			METHODS:
		                        			A retrospective analysis was performed on the clinical data and capsule endoscopy findings of 93 children with hematochezia who were admitted to Children's Hospital of Fudan University from May 2015 to January 2019 and underwent capsule endoscopy. According to the capsule endoscopy findings of the jejunum and the ileum, they were divided into a positive lesion group with 39 patients and a negative lesion group with 54 patients. Related clinical data and the features of lesion on capsule endoscopy were analyzed for the two groups.
		                        		
		                        			RESULTS:
		                        			There were no significant differences in age, sex, duration of capsule endoscopy, gastric transit time, and small intestinal transit time between the positive lesion and negative lesion groups (P>0.05). The positive lesion group had a significantly lower level of hemoglobin than the negative lesion group (P<0.05). Hemoglobin level was negatively correlated with the rate of positive lesions on capsule endoscopy (r=-0.342, P=0.001). Among the 39 patients with positive lesions on capsule endoscopy, the detection of Meckel's diverticulum was the highest (41%), followed by inflammatory bowel disease (21%).
		                        		
		                        			CONCLUSIONS
		                        			Capsule endoscopy has a certain value in detecting small intestinal diseases, especially diseases in the jejunum and the ileum, in children with lower gastrointestinal hemorrhage.
		                        		
		                        		
		                        		
		                        			Capsule Endoscopy
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Gastrointestinal Hemorrhage
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intestinal Diseases
		                        			;
		                        		
		                        			Jejunum
		                        			;
		                        		
		                        			Meckel Diverticulum
		                        			;
		                        		
		                        			Retrospective Studies
		                        			
		                        		
		                        	
8.Adult Ileocolic Intussusception Caused by Diffuse Large B Cell Lymphoma
Joon Woo PARK ; Geun Am SONG ; Dong Hoon BAEK ; Gwang Ha KIM ; Bong Eun LEE ; Moon Won LEE ; Sung Yong HAN ; Young Joo PARK ; Eun Young PARK
The Korean Journal of Gastroenterology 2020;75(1):46-49
		                        		
		                        			
		                        			Intussusception is a medical condition, in which a proximal part of the intestine folds into the distal intestine. Adult intussusceptions are rare and account for approximately 5% of all cases of intussusceptions. The anatomical leading points include tumors, diverticulums, polyps, and strictures in 80-90% of adult intussusceptions, and 65% of colon intussusceptions and 30% of small bowel intussusceptions originate from malignant tumors. Treatments for adult intussusception have not been established, but most cases require surgical treatment. The gastrointestinal tract is the most common extranodal site for non-Hodgkin lymphoma. The symptoms are mostly non-specific, but they rarely lead to complications, such as bleeding, perforation, and intussusception. Furthermore, few cases of primary gastrointestinal lymphomas causing intussusception have been reported. This paper reports a case of small bowel diffuse large B cell lymphoma that caused ileocolic intussusception in a 69-year-old woman with no medical history. She underwent a small bowel resection and received six cycles of adjuvant chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone. Since then, she has been in complete remission.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Chemotherapy, Adjuvant
		                        			;
		                        		
		                        			Colon
		                        			;
		                        		
		                        			Constriction, Pathologic
		                        			;
		                        		
		                        			Cyclophosphamide
		                        			;
		                        		
		                        			Diverticulum
		                        			;
		                        		
		                        			Doxorubicin
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Gastrointestinal Tract
		                        			;
		                        		
		                        			Hemorrhage
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intestines
		                        			;
		                        		
		                        			Intussusception
		                        			;
		                        		
		                        			Lymphoma
		                        			;
		                        		
		                        			Lymphoma, B-Cell
		                        			;
		                        		
		                        			Lymphoma, Non-Hodgkin
		                        			;
		                        		
		                        			Polyps
		                        			;
		                        		
		                        			Prednisone
		                        			;
		                        		
		                        			Rituximab
		                        			;
		                        		
		                        			Vincristine
		                        			
		                        		
		                        	
9.Asymptomatic Bladder Diverticulum Can Develop New Urinary Symptoms after a New Onset of Stroke: a Case Report
Won Jae JO ; Yong Soon YOON ; Eun Sil KIM ; Jun Hyun CHOI ; Kwang Jae LEE
Brain & Neurorehabilitation 2020;13(1):5-
		                        		
		                        			
		                        			Bladder diverticulum can be caused by many varying factors. It is usually asymptomatic in nature and thus often found by chance. In adult males, it can develop as a result of increased intravesicular pressure in the presence of an underlying benign prostatic hyperplasia. We observed a case in which a patient with asymptomatic bladder diverticulum developed new urinary symptoms owing to an underlying neurogenic lower urinary tract disorder which occurred following a cerebral infarction.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Cerebral Infarction
		                        			;
		                        		
		                        			Diverticulum
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Prostatic Hyperplasia
		                        			;
		                        		
		                        			Stroke
		                        			;
		                        		
		                        			Urinary Bladder
		                        			;
		                        		
		                        			Urinary Bladder, Neurogenic
		                        			;
		                        		
		                        			Urinary Tract
		                        			
		                        		
		                        	
10.Risk factors predicting development of complications in 72 dogs with esophageal foreign bodies
Bohye SHIN ; Hakhyun KIM ; Dongwoo CHANG ; Ji Houn KANG ; Byeong Teck KANG ; Mhan pyo YANG
Korean Journal of Veterinary Research 2019;59(1):25-31
		                        		
		                        			
		                        			The aim of this study was to determine predictive risk factors implicated in complications in dogs with esophageal foreign bodies. Medical records of 72 dogs diagnosed with esophageal foreign bodies by endoscopy were reviewed retrospectively. Factors analyzed included age; breed; gender; body weight, location, dimension, and type of foreign body; and duration of impaction. To identify risk factors associated with complications after foreign body ingestion, categorical variables were analyzed using the chi-square or Fisher's exact tests and multivariate analysis, as appropriate. Complications secondary to esophageal foreign body ingestion included megaesophagus, esophagitis, perforation, laceration, diverticulum, and pleuritis. Univariate analysis revealed that the location and duration of impaction after foreign body ingestion were associated with an increased risk of esophageal laceration and perforation. Multivariate analysis showed that age, duration of impaction, and foreign body dimension were significant independent risk factors associated with the development of complications in dogs with esophageal foreign bodies. In conclusion, these results showed that longer duration of impaction and larger foreign body dimensions may increase the risks of esophageal laceration, perforation, and plueritis in dogs.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Body Weight
		                        			;
		                        		
		                        			Diverticulum
		                        			;
		                        		
		                        			Diverticulum, Esophageal
		                        			;
		                        		
		                        			Dogs
		                        			;
		                        		
		                        			Eating
		                        			;
		                        		
		                        			Endoscopy
		                        			;
		                        		
		                        			Esophageal Achalasia
		                        			;
		                        		
		                        			Esophageal Perforation
		                        			;
		                        		
		                        			Esophagitis
		                        			;
		                        		
		                        			Foreign Bodies
		                        			;
		                        		
		                        			Lacerations
		                        			;
		                        		
		                        			Medical Records
		                        			;
		                        		
		                        			Multivariate Analysis
		                        			;
		                        		
		                        			Pleurisy
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Risk Factors
		                        			
		                        		
		                        	
            

Result Analysis
Print
Save
E-mail