Two new 2,3-seco triterpenoids from Rubus pirifolius Smith
10.16438/j.0513-4870.2023-0152
- VernacularTitle:红簕钩中两个新的2,3-裂环三萜酸
- Author:
Xiao-yan NING
1
;
Mei-fang HUANG
2
;
Qin-qin LIANG
2
;
Xu FENG
1
;
Chen-yan LIANG
3
;
Jian-fang FENG
4
;
Liu-ping WANG
5
;
Jian-hua WEI
3
Author Information
1. College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China; Key Laboratory of TCM Extraction and Purification and Quality Analysis, Education Department of Guangxi Zhuang Autonomous Region, Nanning 530200, China
2. College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China
3. College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China; Key Laboratory of TCM Extraction and Purification and Quality Analysis, Education Department of Guangxi Zhuang Autonomous Region, Nanning 530200, China; Guangxi Superior Chinese Patent Medicine and National Medicine Development Engineering Technology Research Center, Nanning 530200, China
4. Guangxi Superior Chinese Patent Medicine and National Medicine Development Engineering Technology Research Center, Nanning 530200, China
5. College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China; Guangxi Superior Chinese Patent Medicine and National Medicine Development Engineering Technology Research Center, Nanning 530200, China
- Publication Type:Research Article
- Keywords:
italic>Rubus pirifolius Smith;
2,3-seco triterpene;
chemical composition
- From:
Acta Pharmaceutica Sinica
2023;58(10):3065-3069
- CountryChina
- Language:Chinese
-
Abstract:
Eight compounds were isolated from the ethyl acetate fraction of the 80% aqueous ethanol extract of the roots and stems of Rubus pirifolius Smith by AB-8 macroporous resin, silica gel, ODS, Sephadex LH-20 column chromatography, and semi-preparative HPLC. Their structures were identified by spectral analysis such as 1D/2D NMR, MS, UV, IR and by comparison with literature information as rubussecotriterpene A (1), rubussecotriterpene B (2), cecropiacic acid (3), cecropiacic acid 3-methyl ester (4), alphitolic acid (5), betulinic acid (6), betulin (7), and obtusalin (8). Compounds 1 and 2 are new compounds, and compounds 3-8 were isolated from this plant for the first time.
