Pituitary hyperplasia and Van Wyk Grumbach Syndrome:  A consequence of chronic untreated congenital Hypothyroidism

Author: Deep Dutta ¹ ; Manoj Kumar ¹ ; Rajesh Jain ¹ ; Anubhav Thukral ¹ ; Sujoy Ghosh ¹ ; Satinath Mukhopadhyay ¹ ; Subhankar Chowdhury ¹
Author Information

1. Department of Endocrinology and Metabolism, Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karani Memorial Hospital, Calcutta, India
Publication Type:Journal Article
Keywords: Van Wyk Grumbach Sundrome
MeSH: Hypothyroidism; Puberty, Precocious
From: Journal of the ASEAN Federation of Endocrine Societies 2013;28(1):88-89
CountryPhilippines
Language:English
Abstract: An eight-year, 4-month old Indian girl with low IQ and delayed milestones, presented with headache (4 years), breast development (4 months), and menstrual bleeding for 22 days. Examination revealed short stature [height: 91.5 cm; SD score: -5.59], coarse dry skin, umbilical hernia (arrow), delayed reflexes, Tanner’s stage-3 breasts, absent pubic and axillary hair
Full text:58-Article Text-288-1-10-20140524.pdf