Primary hypoparathyroidism and non-functioning pituitary adenoma: An incidental coexistence?
- Author:
Lit Sin Yong
1
;
Noorlita Adam
1
Author Information
- Publication Type:Journal Article
- Keywords: Pituitary macroadenoma; Primary hypoparathyroidism; Endocrine autoimmunity,
- MeSH: Hypopituitarism; Autoimmune Hypophysitis; DiGeorge Syndrome
- From: Journal of the ASEAN Federation of Endocrine Societies 2014;29(1):86-89
- CountryPhilippines
- Language:English
- Abstract: Primary hypoparathyroidism is caused by a group of heterogeneous conditions in which hypocalcemia and hyperphosphatemia occur as a result of deficient parathyroid hormone (PTH) secretion. The most common cause is surgical excision and damage to the parathyroid gland(s). Nonetheless, autoimmune endocrine disorder of primary hypothyroidism has been well-described in polyglandular autoimmune syndromes (PAS).1 Its association with pituitary lesion may be autoimmune lymphocytic hypophysitis as the cause for pituitary disorder. In this report, we encountered a patient with primary hypoparathyroidism who had a non-functioning pituitary tumour. It was confirmed as pituitary adenoma rather than lymphocytic hypophysitis from the histopathological examination. To our knowledge, this is the first reported case of non-functioning pituitary macroadenoma and primary hypoparathyroidism.
- Full text:121-Article Text-589-1-10-20140531.pdf
