Potency of Anosmia and Ageusia as Covid-19 Prognostic Factors: A Systematic Review
https://doi.org/10.47836/mjmhs.19.5.30
- Author:
Theresia Feline Husen
1
;
Ruth Angelica
1
;
R. Muhammad Kevin Baswara
1
Author Information
1. Faculty of Medicine, University of Indonesia, Pondok Cina, Beji, Depok City, 16424, West Java, Indonesia
- Publication Type:Other Types
- Keywords:
Anosmia, Ageusia, Covid-19, Prognostic factors
- From:Malaysian Journal of Medicine and Health Sciences
2023;19(No.5):211-217
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: The clinical signs of COVID-19 include ageusia and anosmia. Anosmia and ageusia haven’t been
evaluated as prognostic factors in any prior studies, though. Therefore, the purpose of this review is to assess the effectiveness of ageusia and anosmia as prognostic indicators in COVID-19 patients. Methods: Literature was collected
from various databases systematically using the PRISMA until May 25th,2022. The screening process was performed
based on inclusion and exclusion criteria, before being analyzed qualitatively. The risk of bias was assessed using
Newcastle-Ottawa Quality Assessment Scale converted by AHRQ. Results: Anosmia and ageusia could be used as
the indicator for the good prognostic associated with lower mortality, milder trajectory rate, ICU, and hospital admission risk, and shorter length of stay. Anosmia and ageusia have shown high prevalence to predict a prognosis for
the COVID-19 infection. Although COVID-19 prognosis also depends on the other lying conditions, patients with
anosmia or ageusia had a lower mortality risk due to the lower body mechanism and cell inflammation mechanism
toward the viral load that may not lead to the maladaptive cytokine release in response to infection generally called
as a cytokine storm. Conclusion: In COVID-19 patients, anosmia and ageusia have been shown to be indicators of a
favorable prognosis due to lower disease severity, mortality, risk of ICU and hospital admission, and shorter duration
of stay. Therefore, in order to determine the prognosis, it is important to assess the clinical symptoms of the patients.
- Full text:11.2023my1632.pdf
