Progress of researches on the role and mechanisms of non - coding RNA in Angiostrongylus cantonensis infection
10.16250/j.32.1374.2022283
- VernacularTitle:非编码RNA在广州管圆线虫感染中作用 和机制研究进展
- Author:
Donghui CHENG
1
;
Zhongqiu LI
1
;
Wenbo ZENG
1
;
Tiange JIANG
2
;
Yunhai GUO
1
;
Yi ZHANG
3
Author Information
1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (National Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China
2. School of Global Health, National Center for Tropical Disease Research and Shanghai Jiao Tong University, Shanghai 200025, China
3. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (National Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China; School of Global Health, National Center for Tropical Disease Research and Shanghai Jiao Tong University, Shanghai 200025, China
- Publication Type:Journal Article
- Keywords:
Angiostrongylus cantonensis;
Non-coding RNAs;
Regulatory role;
Molecular mechanism
- From:
Chinese Journal of Schistosomiasis Control
2023;35(4):407-412
- CountryChina
- Language:Chinese
-
Abstract:
Angiostrongylus cantonensis is a food-borne zoonotic parasite, and human infection may cause eosinophilic meningitis. Non-coding RNAs (ncRNAs) may regulate physiological and pathological processes at multiple biological levels; however, there are few studies pertaining to the regulatory role of ncRNAs in A. cantonensis infection. Based on publications retrieved from PubMed, Wanfang Data and CNKI, the regulatory role of ncRNAs in A. cantonensis infections mainly includes immune responses, cell apoptosis and signaling transduction, and ncRNAs may serve as biomarkers for diagnosis of angiostrongyliasis. This review summarizes the main roles of ncRNAs in A. cantonensis infections and the underlying mechanisms, so as to provide insights into diagnosis and treatment of angiostrongyliasis.
