Review of the Benefits of Eggshell Content in Body Tissue  Structure Repair
	    		
	    			
	    			
		        		
			        		
		        		
			        
		   		
		   		
		   			
		   		
	    	
    	 
    	https://doi.org/10.47836/mjmhs.19.2.39
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Hastuti Herman
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Rahmawati Minhajat
			        		
			        		
			        		
			        			2
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Mirna Muis
			        		
			        		
			        		
			        			3
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Batari Todja Umar
			        		
			        		
			        		
			        			4
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Muhammad Husni Cangara
			        		
			        		
			        		
			        			5
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Andi Alfian Zainuddin
			        		
			        		
			        		
			        			6
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Biomedical Science Study Program, Graduate School, Universitas Hasanuddin, Makassar, Indonesia
			        		
			        			2. Department of Histology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia&Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
			        		
			        			3. Department of Histology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia&Department of Radiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
			        		
			        			4. Department of Histology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia&Department of Ophthalmology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
			        		
			        			5. Department of Anatomical Pathology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
			        		
			        			6. Department of Public Health Sciences, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Review
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Eggshell, Eggshell membrane, Body tissue repair
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:Malaysian Journal of Medicine and Health Sciences
	            		
	            		 2023;19(No.2):278-285
	            	
            	
 
            
            
            	- CountryMalaysia
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Eggshell (ES) is a waste material that cannot be consumed with low economic value. ES mainly contains calcium 
carbonate (CaCO3) and an organic matrix in the form of proteins, glycoproteins, and proteoglycans. Meanwhile, 
the eggshell membrane (ESM) contains osteopontin collagen, fibronectin, keratin, histones, avian beta defensins, 
ovocalyxin-36, apolipoproteins, protocadherin, chondroitin sulfate, ovotransferrin, hyaluronic acid, and sialic acid 
as well as various amino acids. Recently, ES has been widely used in industry, agriculture, food, and medical fields. 
The potential of ES in the medical field is interesting to discuss, especially in relation to tissue repair. Efforts to reduce 
the prevalence of wounds that generally originate from acute wounds but become chronic due to various factors 
that are neglected in their management. In particular, this review will describe the benefits of ES content in repairing 
body tissues. ES-derived active ingredients such as CaCO3, brushite, and hydroxyapatite exhibit osteoconductive 
properties that promote bone regeneration. Calcium ions can increase insulin and leptin sensitivity in the liver and 
can induce repair of acute kidney injury. Meanwhile, ESM contributes positively to neural tissue repair and plays an 
important role in wound healing, response to external stimuli, defense response, inflammatory response, cell-substrate adhesion, promoting cell growth, migration, differentiation, and tissue remodeling. 
				        	
				        
				    
			    
 
	        
	        
	        	- Full text:11.2023my1489.pdf