Epidemiological characteristics and risk factors of bronchiectasis in patients with chronic obstructive pulmonary disease in Suining area
10.3969/j.issn.1006-2483.2023.05.032
- VernacularTitle:遂宁地区慢性阻塞性肺疾病患者支气管扩张流行病学特征及危险因素
- Author:
Ying LONG
1
;
Xiaobin LUO
1
;
Rong LI
1
;
Yu YAO
1
;
Jianping HU
2
Author Information
1. Respiratory Department of Suining Central Hospital , Suining , Sichuan 629000 ,China
2. Department of Emergency , Suining Central Hospital , Suining , Sichuan 629000, China
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Bronchiectasis;
Epidemiological characteristics
- From:
Journal of Public Health and Preventive Medicine
2023;34(5):137-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the epidemiological characteristics and risk factors of bronchiectasis in patients with chronic obstructive pulmonary disease (COPD) in Suining area, and to provide theoretical basis for COPD prevention and treatment of bronchiectasis. Methods A total of 582 patients with ACUTE exacerbation of COPD (AECOPD) admitted to grade A Hospitals in Suining area from 2019 to 2020 were selected as the investigation objects. According to whether the patients had bronchiectasis, they were divided into control group (without bronchiectasis, n=485) and observation group (with bronchiectasis, n=97). The risk factors of bronchiectasis in COPD patients were analyzed by univariate analysis and logistic regression. The clinical data of the two groups were compared, including age, sex, whether there were other diseases, respiratory tract infection, proportion of purpuric sputum, colonization rate of Pseudomonas aeruginosa. Results Of 16.84% (49/291) AECOPD patients occurred Bronchiectasis. The colonization rate of Pseudomonas aeruginosa in observation group was significantly higher than that in control group (P<0.05). The values of FVC and FEV1/FVC in observation group were significantly lower than those in control group (P<0.05). The levels of serum CRP and PCT in the observation group were significantly higher than those in the control group (P<0.05). Male (OR=2.515), high proportion of GOLD grade III/IV (OR=3.654), smoking (OR=3.472), diabetes (OR=3.829) and bacterial infection (OR=4.159) were independent risk factors for bronchiectasis in COPD patients (P<0.05). Conclusion COPD patients in Suining area have a high risk of bronchiectasis.The lung function was declined significantly.It has a high colonization rate of Pseudomonas aeruginosa. Patients who are male, have a high proportion of GOLD class III/IV, smoke, have diabetes, and have bacterial infections should be given interventions that can reduce the risk of bronchiectasis in COPD patients.
