Progress of long non-coding RNA in treatment of triple-negative breast cancer
10.3760/cma.j.cn115355-20220213-00072
- VernacularTitle:长链非编码RNA在三阴性乳腺癌治疗中的研究进展
- Author:
Simin ZHENG
1
;
Jinnan GAO
Author Information
1. 山西医科大学第三医院乳腺外科（山西白求恩医院山西医学科学院同济山西医院），太原 030032
- Keywords:
Long non-coding RNA;
Breast neoplasms;
Tumor markers, biological
- From:
Cancer Research and Clinic
2022;34(12):947-949
- CountryChina
- Language:Chinese
-
Abstract:
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized with intense invasion, early recurrence, rapid progression, short survival time and easy invasion and metastasis. Due to its high heterogeneity and lack of specific targeted therapy, its pathogenesis has become an important target of current research. Long non-coding RNA (lncRNA) is a class of non-coding RNA with more than 200 nucleotide sequences in length. More and more studies have found lncRNA plays an important role in the occurrence and progression of TNBC. This article reviews the biological characteristics of lncRNA, the current research status of the expression, function and regulation of lncRNA in TNBC to provide theoretical basis for the clinical diagnosis and treatment of TNBC.
