Efficacy of intense pulse light and M22-ResurFx fractional laser on lateral crow's feet
10.3760/cma.j.issn.1671-0290.2022.06.017
- VernacularTitle:强脉冲光联合非剥脱点阵激光对鱼尾纹的效果研究
- Author:
Yue XIN
1
;
Dongmei LI
Author Information
1. 首都医科大学附属北京同仁医院北京同仁眼科中心 北京市眼科学与视觉科学重点实验室,北京 100730
- Keywords:
Lasers;
Intense pulsed light therapy;
Comparative effectiveness research;
Non-ablative fractional laser;
Crow's feet
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2022;28(6):512-516
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and patients' satisfaction of the intense pulse light (IPL) and M22-Resur Fx non-ablative fractional laser (NAFL) for the treatment of lateral static crow's feet.Methods:A prospective split-face, randomized, controlled study of 60 consecutive patients with lateral static crow's feet was performed. The patients aged 30 to 55 years, who were enrolled in the Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University from January 2018 to January 2020. The two sides of each patient's face were randomized to receive different treatment, and according to their treatment, the patients were divided into 3 groups with 20 cases each: Group A, in which 20 patients' one side face was treated with IPL, and other side was treated with NAFL; Group B, in which one side face was treated with IPL, and another side was treated with IPL immediately followed by NAFL; Group C, in which one side face was treated with NAFL, and another side was treated with IPL immediately followed by NAFL. The improvements including the water content of stratum corneum of skin and the patients' satisfaction, as well as the improvement of the lateral static crow's feet were evaluated.Results:The IPL plus NAFL combined treatment group and the NAFL treatment group showed the effective rate of the improvement for lateral static crow's feet of patients on days 60 and 90 was statistically significant ( P<0.05) compared with that before the treatment. And the improvement for lateral static crow's feet of patients on days 60 and 90 in combined treatment side was significantly different from either NAFL side ( P<0.05). 60 days and 90 days after treatment, the satisfaction of combined treatment side was significantly higher than that of either NAFL side or IPL side ( P<0.05). Conclusions:The treatment with an optimized IPL immediately followed by a NAFL is clinically superior to those with the NAFL or IPL alone for improving the lateral static crow's feet of patients. The satisfaction treated by NAFL combined with IPL is higher than using the NAFL or IPL alone.