Application of mass spectrometry in clinical laboratory in North America
10.3760/cma.j.cn114452-20230208-00079
- VernacularTitle:质谱技术在北美临床检验中的应用
- Author:
X. Michael CHEN
1
Author Information
1. 病理学和检验医学系，不列颠哥伦比亚大学，温哥华，加拿大
- Keywords:
Mass spectrometry;
Clinical Laboratory Techniques;
North America
- From:
Chinese Journal of Laboratory Medicine
2023;46(8):768-774
- CountryChina
- Language:Chinese
-
Abstract:
Detection of early drug abuse has driven the use of mass spectrometry in clinical laboratories across North America. Mass spectrometry-based assays have been increasingly implemented in various clinical disciplines for their advantages in high analytical sensitivity, specificity and multiplexing capacity. Mass spectrometry is now routinely used for the clinical analysis of small molecule compounds, peptides, proteins, clinical toxicology and microbiology. Although more FDA-approved platforms and reagents need to be commercially available, there is no doubt that mass spectrometry technology has demonstrated rich clinical applications.
