Research update on the clinical application of the quantity and quality of high-density lipoprotein in atherosclerosis
10.3760/cma.j.cn114452-20221101-00646
- VernacularTitle:高密度脂蛋白量和质在动脉粥样硬化中的临床应用
- Author:
Jiang LI
1
;
Yun ZHOU
;
Yongtong CAO
Author Information
1. 中日友好医院检验科，北京100029
- Keywords:
High density lipoprotein;
Atherosclerosis;
Cardiovascular disease
- From:
Chinese Journal of Laboratory Medicine
2023;46(7):667-671
- CountryChina
- Language:Chinese
-
Abstract:
Recent research evidence challenges the hypothesis that high density lipoprotein (HDL) has a protective effect on atherosclerosis. Due to the heterogeneity of HDL particle composition and the diversity of HDL functions, the evaluation of HDL particle composition and the detection of HDL function might overcome the deficiency from the measurement of single high-density lipoprotein cholesterol (HDL-C) level. This review briefly introduced the detection method and clinical application for the "quantity" of HDL, and focused on the current status of clinical application and the future development trend of related detection method for the structure and function of HDL. It is postulated that the evaluation of the "quality" of HDL may become the routine method of HDL detection in the future.
