Application prospect of nuclear magnetic resonance spectroscopy in clinical laboratory examination
10.3760/cma.j.cn114452-20220518-00300
- VernacularTitle:核磁共振波谱技术在临床检验的应用前景
- Author:
Hua YAN
1
;
Xiaoke HAO
Author Information
1. 西安区域医学检验中心，西安 712000
- Keywords:
Nuclear magnetic resonance spectroscopy;
Clinical laboratory techniques;
Disease diagnosis;
Health management
- From:
Chinese Journal of Laboratory Medicine
2023;46(4):421-427
- CountryChina
- Language:Chinese
-
Abstract:
Nuclear magnetic resonance spectroscopy (NMRS) is a branch of spectroscopy, which can be used to determine the number, type and relative position of components in the mixture. Due to its high throughput, high sensitivity and high stability, especially its "fingerprint", non-destructive and non-biased detection of metabolites, NMRS has become one of the most commonly used analytical and detection techniques in metabolomics. Based on the research of clinical laboratory application, this review briefly expounds the technical principle of nuclear magnetic resonance spectroscopy, introduces the development and latest research results of nuclear magnetic resonance spectroscopy in biomedical application fields such as blood lipid analysis, tumor detection, prediction of mental and nervous system diseases, infectious diseases, nutrition and health management, and discusses the development prospect of clinical translational medicine.
