Research progress in neutrophil extracellular traps in obstetrics
10.3760/cma.j.cn113903-20220512-00473
- VernacularTitle:中性粒细胞胞外诱捕网在产科相关疾病中的研究进展
- Author:
Di SHEN
1
;
Xietong WANG
Author Information
1. 山东省妇幼保健院妇产科，济南 250014
- Keywords:
Pregnancy;
Extracellular traps;
Pre-eclampsia;
Diabetes, gestational;
Premature birth
- From:
Chinese Journal of Perinatal Medicine
2022;25(12):991-995
- CountryChina
- Language:Chinese
-
Abstract:
Neutrophils plays an essential role in innate immunity. Neutrophil extracellular traps (NETs) are released by activated neutrophils in response to infection. However, excessive NETs can result in body dysfunction and organ damage and participate in several pathological conditions. This paper mainly focuses on the formation, regulatory mechanism and role of NETs in obstetric diseases, such as preeclampsia, gestational diabetes mellitus and preterm birth, and listed the current medications used to block the formation of NETs in obstetrics.
