Effect of peroxisome proliferator-activated receptor γ on skin physiological and pathological processes
- VernacularTitle:过氧化物酶体增殖物激活受体γ对皮肤生理功能和病理过程的影响
- Author:
Panpan LIAN
1
;
Jun LIU
;
Zhonglan SU
;
Hongwei WANG
Author Information
- Keywords: Peroxisome proliferator-activated receptors; Inflammation; Wounds and injuries; Skin aging; Skin neoplasms; Psoriasis
- From: Chinese Journal of Dermatology 2023;56(4):365-368
- CountryChina
- Language:Chinese
- Abstract: Peroxisome proliferator-activated receptors (PPARs) are widely involved in lipid metabolism, glucose metabolism, cell growth and differentiation, and inflammation in the human body. PPARγ agonists can inhibit skin inflammatory response, protect epidermal barrier function, and repair skin injury. This review summarizes various roles of PPARγ in skin biology, and discusses its function in skin diseases, such as psoriasis and skin tumors.
