Application of the interleukin-23 inhibitor guselkumab in the treatment of psoriasis
- VernacularTitle:白细胞介素23抑制剂古塞奇尤单抗在银屑病治疗中的应用
- Author:
He HUANG
1
;
Xuejun ZHANG
Author Information
- Keywords: Psoriasis; Interleukin-23; Guselkumab
- From: Chinese Journal of Dermatology 2023;56(2):181-184
- CountryChina
- Language:Chinese
- Abstract: Guselkumab is the first monoclonal antibody that selectively targets interleukin (IL) -23. Several randomized controlled clinical trials have demonstrated that it is highly effective and safe in the treatment of moderate to severe plaque psoriasis, and can significantly improve the quality of life of patients. This review summarizes the action mechanisms of IL-23 and guselkumab, as well as the application of guselkumab in the treatment of psoriasis.
