Advances of microglia and their exosomes in central neurodegenerative diseases
10.3760/cma.j.issn.0254-9026.2023.02.016
- VernacularTitle:小胶质细胞及其外泌体在中枢神经退行性疾病中的研究进展
- Author:
Kaiyue SHAN
1
;
Rui DONG
;
Gaofeng ZHANG
;
Huailong CHEN
;
Bingqi WANG
;
Mingshan WANG
Author Information
1. 大连医科大学研究生院，大连 116044
- Keywords:
Microglia;
Exosomes;
Central neurodegenerative diseases
- From:
Chinese Journal of Geriatrics
2023;42(2):219-224
- CountryChina
- Language:Chinese
-
Abstract:
Microglia are widely present in the central nervous system and participate in various pathophysiological processes.They play an important role in degenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.In recent years, the study of exosomes produced by microglia activation involved in the pathophysiological processes of various diseases has attracted extensive attention, but the role of exosomes has not been fully clarified.This article reviewed the characteristics and functions of microglia, the characteristics and functions of microglia-derived exosomes and their roles in central neurodegenerative diseases.
