Application of 4DCT-based lung functional imaging in radiotherapy for lung cancer
10.3760/cma.j.cn113030-20220414-00142
- VernacularTitle:基于4DCT的肺功能成像在肺部肿瘤放射治疗中的应用进展
- Author:
Wenjing ZHONG
1
;
Ying LI
;
Haixia CUI
Author Information
1. 重庆医科大学附属第一医院肿瘤科，重庆 400016
- Keywords:
Lung neoplasms / radiotherapy;
Radiation pneumonitis;
Four-dimensional computed tomography;
Functional lung;
Ventilation image
- From:
Chinese Journal of Radiation Oncology
2023;32(5):481-487
- CountryChina
- Language:Chinese
-
Abstract:
Radiation pneumonia is a side effect that cannot be ignored in the current radiation therapy for lung cancer. At present, there are studies and reports of the introduction of functional imaging technology into lung cancer radiotherapy plans, in which 4DCT has better application prospects in radiotherapy for lung cancer because of its advantages of simple operation, high spatial resolution and no additional cost, etc. Compared with single-photon emission computed tomography (SPECT)-CT, positron emission tomography (PET)-CT, MRI has a better application prospect in radiotherapy of lung cancer. The use of 4DCT to obtain the patient's lung function status can predict radiation pulmonary toxicity and assist clinicians to deliver prompt interventions. Moreover, it can help carry out radiotherapy for functional lung avoidance, mitigate the damage of normal lung tissues, and alleviate chest toxicity, which may have wider application value in the future. In this article, research progress on functional lung imaging algorithms based on 4DCT and the application of radiation therapy for lung cancer was reviewed.
