Rare cerebral small vessel disease and retinal vascular abnormalities
10.3760/cma.j.cn431274-20230220-00187
- VernacularTitle:罕见脑小血管病与视网膜血管异常
- Author:
Zhangwanyu WEI
1
;
Xufeng ZHAO
;
Weihong YU
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院眼科；中国医学科学院眼底病重点实验室，北京 100730
- Keywords:
Cerebral small vessel diseases;
Retinal vessels;
CADASIL;
Cerebral amyloid angiopathy;
Moyamoya disease
- From:
Journal of Chinese Physician
2023;25(4):507-509,515
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease (CSVD) is a series of clinical, imaging, and pathological syndromes resulting from various etiologies affecting small arteries (microarteries, capillaries, microvenules, and small veins in the brain). The diagnosis of CSVD is based on imaging presentations, but the high cost and bleeding risk of cranial imaging methods make the diagnosis of rare CSVD more difficult. Retinal vessels are the only vasculature visible in vivo and share anatomical and embryological features with small brain vessels. Retinal vascular abnormalities have been shown to exist in rare CSVD such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), cerebral amyloid angiopathy (CAA) and moyamoya disease (MMD). Retinal vascular examination may provide new ideas for the study of rare CSVD.
