Pay attention to the association of systemic lupus erythematosus with ocular fundus impairment and systemic condition

VernacularTitle:重视系统性红斑狼疮伴眼底损害与全身疾病的相关性
Author: Lihui MENG ¹ ; Yinhan WANG ; Youxin CHEN
Author Information

1. 北京协和医院眼科，中国医学科学院眼底病重点实验室，北京　100730
Keywords: Lupus erythematosus, systemic; Retinal vasculitis; Choroid diseases; Tomography, optical Coherence
From: Journal of Chinese Physician 2023;25(4):481-485
CountryChina
Language:Chinese
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple systems throughout the body, which may cause serious visual impairment when the fundus is involved. In recent years, " looking at health through the eyes" is a hot research topic. Studies on SLE have shown that retinopathy is highly correlated with disease activity. Even there is no clinical manifestation, changes in retinal microvessel density and structure also show a certain correlation with the course of SLE and other organs′ involvement. Therefore, the evaluation of fundus features in SLE patients is not only helpful for early intervention and improvement of patients′ visual function prognosis, but also of great significance for the diagnosis of SLE and prediction of other systems′ impairment.