The role of thermosensitive transient receptor potential vanilloid channel in the dissimilation of itching sensitized by warm in atopic dermatitis
10.3760/cma.j.cn431274-20220630-00613
- VernacularTitle:热敏TRPV通道在特应性皮炎温热痒觉异化中的作用
- Author:
Yunsheng ZHAO
1
;
Huimin ZHANG
;
Dongming WANG
Author Information
1. 上海中医药大学附属曙光医院皮肤科，上海 200126
- Keywords:
Dermatitis, atopic;
Thermosensitive TRPV channels;
Pruritus
- From:
Journal of Chinese Physician
2023;25(3):464-467
- CountryChina
- Language:Chinese
-
Abstract:
Atopic dermatitis (AD) is an inflammatory skin disease characterized by itch. Transient receptor potential vanilloid (TRPV) receptor subtype channel can be activated by different ranges of harmless temperature, and plays an important role in the warm itching in AD. Inhibitors of TRPV channel can alleviate the symptoms of AD, and may be used as a new target for treatment. This paper introduces the role of thermosensitive TRPV channel in the alienation of itching sensitized by warm in AD.
