Microglia involved in restricted and repetitive behaviors
10.3760/cma.j.cn371468-20220926-00572
- VernacularTitle:小胶质细胞与重复刻板行为
- Author:
Rui LI
1
;
Yizhuo WANG
;
Hongen WEI
Author Information
1. 山西医科大学第五临床医学院，山西省人民医院神经内科，太原 030012
- Keywords:
Microglia;
Restricted and repetitive behaviors;
Neuropsychiatric diseases
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2023;32(2):188-192
- CountryChina
- Language:Chinese
-
Abstract:
Restricted and repetitive behaviors is the characteristic clinical manifestation of many neuropsychiatric diseases, which seriously affects the work, study and daily communication of patients, and brings huge mental and economic burden to the family and society.Its causes are complex and its manifestations are diverse.Current studies have shown that microglia is closely related to the occurrence of restricted and repetitive behaviors, and the in-depth study of microglia has become a research hotspot to explore the mechanism of restricted and repetitive behaviors.In recent years, studies have found that restricted and repetitive behaviors of various neuropsychiatric diseases (such as frontotemporal dementia, obsessive-compulsive disorder, autism spectrum disorder) are related to microglia.However, reliable evidence for the exact mechanism of microglia involved in restricted and repetitive behaviors remains lacking.This article reviews the recent research progress of microglia involved in restricted and repetitive behaviors.It is expected to provide a new theoretical basis and therapeutic targeting cell for the development and treatment of neuropsychiatric diseases related to restricted and repetitive behaviors in the future.
