Carbomer hemorrhoid gel for the treatment of second-degree internal hemorrhoid bleeding
10.3760/cma.j.cn341190-20220209-00105
- VernacularTitle:卡波姆痔疮凝胶治疗Ⅱ度内痔出血的临床研究
- Author:
Tuanyou XIAO
1
;
Zhonghai LI
;
Nuge CHEN
;
Jiali LIU
;
Rong WANG
Author Information
1. 珠海市中西医结合医院肛肠科，珠海 519000
- Keywords:
Hemorrhoids;
Hemorrhage;
Acrylic resins;
Polymers;
Administration,rectal;
Jellies;
Intestinal mucosa;
Repair;
Regeneration;
Treatment outcome
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(4):592-595
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy of carbomer hemorrhoid gel in the treatment of second-degree internal hemorrhoid bleeding.Methods:A total of 160 anorectal outpatients with second-degree internal hemorrhoid bleeding who received treatment in Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine from January 2017 to January 2021 were included in this study. They were randomly divided into an observation group and a control group ( n = 80/group). In the observation group, carbomer hemorrhoid gel was used to plug the anus, while in the control group, a hemorrhoid suppository was used to plug the anus. All patients were treated for 7 days. Clinical efficacy was compared between the two groups. Results:After 4 days of treatment, the bleeding score in the observation group was lower than that in the control group [1(0) point vs. 2(1) points, Z = -6.70, P < 0.05). After 7 days of treatment, the bleeding score in the observation group was significantly lower than that in the control group [0(1) point vs. 1(1) point, Z = -4.73, P < 0.05]. After 4 days of treatment, there was no significant difference in the size score of the hemorrhoids between the two groups ( P > 0.05). After 4 days of treatment, the size score of hemorrhoids in the control group did not differ significantly compared with before treatment ( P > 0.05). After 4 days of treatment, the size score of hemorrhoids in the observation group differed significantly compared with before treatment ( Z = -3.16, P < 0.05). After 7 days of treatment, the size score of the hemorrhoids in the observation group was lower than that in the control group [1(1) point vs. 1(0) point, Z = -4.48, P < 0.05]. The total response rate in the observation group was significantly higher than that in the control group [97.5% (78/80) vs. 75% (60/80), Z = -4.50, P < 0.05]. Conclusion:Carbomer hemorrhoid gel is a new drug used to treat hemorrhoids. It has a new dosage form, has no stimulation to the rectum, and is safe to use. Carbomer hemorrhoid gel is highly effective on second-degree internal hemorrhoid bleeding and deserves clinical popularization.
