Research progress on circular RNA in fundus oculi proliferative diseases
10.3760/cma.j.cn115989-20200428-00295
- VernacularTitle:环状RNA与眼底增生性疾病的研究进展
- Author:
Yimin WANG
1
;
Xiaodong SUN
Author Information
1. 上海交通大学附属第一人民医院眼科，上海 200080
- Keywords:
Circular RNA;
Ophthalmology;
Diabetic retinopathy;
Proliferative vitreoretinopathy
- From:
Chinese Journal of Experimental Ophthalmology
2023;41(5):516-519
- CountryChina
- Language:Chinese
-
Abstract:
Fundus oculi proliferative diseases, such as choroidal neovascularization, diabetic retinopathy, and proliferative vitreoretinopathy, are characterized by cell proliferation and neovascularization.It can lead to damage to the ocular structure and visual acuity.Circular RNA (CircRNA) is a non-coding endogenous RNA, which has been confirmed to be involved in the pathophysiological process of many ophthalmic diseases by recent studies.Thus, circRNA may become a promising target of fundus oculi proliferative diseases.This review concluded the physiological function of circRNA and its role in the physiological and pathological process of diabetic retinopathy, proliferative vitreoretinopathy and glaucoma-related glia proliferation.
