Several problems in the diagnosis and treatment of neonatal bacterial meningitis
10.3760/cma.j.cn101070-20210315-00308
- VernacularTitle:新生儿细菌性脑膜炎诊治中的几个问题
- Author:
Shaojie YUE
1
Author Information
1. 中南大学湘雅医院新生儿科，长沙 410008
- Keywords:
Bacterial meningitis;
Cerebrospinal fluid;
Antibiotics;
Intracranial hypertension;
Brain edema;
Infant, newborn
- From:
Chinese Journal of Applied Clinical Pediatrics
2023;38(3):192-197
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal bacterial meningitis remains a common and life-threatening disease in newborns, with high mortality and morbidity.Despite its declining incidence in recent years, the rate of severe sequelae shows slight changes.The clinical manifestation of neonatal bacterial meningitis is atypical, and thus its diagnosis requires cerebrospinal fluid examination.Early detection and effective antibiotic treatment are the key to improve the survival rate.In addition, neonatal bacterial meningitis is often complicated with brain edema and intracranial hypertension, which would result in cerebral ischemia and hypoxia, and further aggravate brain injury.Therefore, more attention should be paid to the prevention and treatment of brain edema and intracranial hypertension while adopting antibiotic therapy in the treatment of neonatal bacterial meningitis.
