Interstitial implantation of radioactive seeds for pancreatic cancer pain management

VernacularTitle:放射性粒子组织间植入治疗胰腺癌疼痛疗效分析
Author: Yong ZHOU ¹ ; Yunpeng SHI ; Xin XIANG ; Rongnan ZHAI ; Baodong GAI
Author Information

1. 吉林大学中日联谊医院胃肠结直肠肛门外科，长春　130031
Keywords: Pancreatic cancer; Radioactive seeds
From: Chinese Journal of Endocrine Surgery 2023;17(3):282-285
CountryChina
Language:Chinese
Abstract: Objective:To assess the effectiveness and characteristics of intratumoral radioactive seed implantation in pancreatic cancer pain management.Methods:Clinical data of 160 patients with pancreatic cancer receiving radioactive seed implantation were retrospectively analyzed. Both pre- and postoperative pain intensities were evaluated using the visual analog scale (VAS) .Results:About 71.88% (115) of 160 patients experienced abdominal or low back pain. Postoperative pain in 104 patients was relieved at various degrees after radioactive seed implantation with an analgesic efficacy of 90.43% (the efficacy for abdominal and low back pain relief was 86.52% and 96.34%, respectively). The between-group difference was statistically significant. Pain relief was observed 1-7 days postoperatively, and the maximal degree of pain relief was achieved 2-14 days after treatment initiation.Conclusion:Intratumoral implantation of radioactive seeds was microinvasive, quick-acting, and effective in pancreatic cancer pain management.