Gut microbiome and tumor immunotherapy
10.3760/cma.j.cn371439-20230413-00083
- VernacularTitle:肠道菌群与肿瘤免疫治疗
- Author:
Ciliang GUO
1
;
Chunping JIANG
;
Junhua WU
Author Information
1. 南京大学医学院，南京 210008
- Keywords:
Neoplasms;
Immunotherapy;
Gastrointestinal microbiome;
Immune checkpoint inhibitors;
Adoptive T cell therapy
- From:
Journal of International Oncology
2023;50(7):432-436
- CountryChina
- Language:Chinese
-
Abstract:
Neoplasms immunotherapy has made a major breakthrough in the clinical practice of refractory tumor. However, there are still individual differences in treatment results and drug resistance in clinical application. Gastrointestinal microbiome is gradually recognized as an immunoregulatory factor in recent years, and more and more studies have focused on its influences on the efficacy of tumor immunotherapy. Targeting gastrointestinal microbiota to improve the response of tumor patients to immunotherapy has potential clinical application value.
