Progress on the role of circRNAs in lung development
10.3760/cma.j.issn.1673-4408.2023.05.006
- VernacularTitle:circRNAs在肺发育中的作用研究进展
- Author:
Yanqing SHEN
1
;
Fei BEI
Author Information
1. 上海交通大学医学院附属上海儿童医学中心新生儿科 200127
- Keywords:
circular RNAs;
Lung development;
Bronchopulmonary dysplasia
- From:
International Journal of Pediatrics
2023;50(5):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Many circular RNAs(circRNAs)have been discovered and identified as noncoding RNA in various organisms in a specie-, tissue-, disease-and developmental stage-specific manner, and have been demonstrated to play essential roles in myriad life processes, such as embryo and tissue development, aging, insulin secretion, vascular disease and cancer.The normal development of lung morphology, structure and function is the physiological basis of breath.Accumulating evidences have been demonstrated that circRNAs might be involved in lung development and play important roles in lung development and related diseases like bronchopulmonary dysplasia(BPD).This review will summarize the biological functions of circRNAs and focus particularly on the potential implications of circRNAs in lung development and BPD.
