Synergetic effect of temperature and PM2.5 on mortality of cardiovascular and cerebrovascular diseases
10.19428/j.cnki.sjpm.2023.22790
- VernacularTitle:气温与PM2.5协同作用对心脑血管疾病死亡的影响研究
- Author:
Sixu YANG
1
;
Li PENG
1
;
Xiaofang YE
1
;
Dandan YANG
1
;
Yajie ZHANG
2
;
Yi ZHOU
3
Author Information
1. Yangtze River Delta Center for Environmental Meteorology Prediction and Warning， Shanghai 200030，China
2. Key Laboratory of South China Sea Meteorological Disaster Prevention and Mitigation of Hainan Province， Haikou， Hainan 570100，China
3. Shanghai Pudong New Area Center for Disease Control and Prevention， Shanghai 200136，China
- Publication Type:Journal Article
- Keywords:
temperature;
PM2.5;
cardiovascular and cerebrovascular disease;
synergetic effect
- From:
Shanghai Journal of Preventive Medicine
2023;35(7):660-666
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the synergetic effect of temperature and PM2.5 on cardiovascular and cerebrovascular diseases. MethodWe collected cardiovascular and cerebrovascular death cases，air pollution and meteorological data during the same period in Pudong New Area from 2013 to 2018.We used generalized additive models （GAMs） with poisson regression including non-stratification model， nonparametric bivariate response model and pollution-stratified parametric model， to assess the interaction between temperature and PM2.5 and on the number of cardiovascular cerebrovascular and cerebrovascular disease deaths. ResultsThe exposure-response relationship between temperature and the number of cardiovascular and cerebrovascular deaths exhibited "U" type and the most comfortable temperature was 18.9 ℃. When the concentrations of PM2.5 increased by 10 μg·m-3， the deaths of total， male， female， ≤75 years and >75 years increased， respectively， by 0.60%（95%CI： 0.30%‒0.91%）， 0.77%（95%CI：0.34%‒1.20%）， 0.46%（95%CI：0.05%‒0.86%）， 0.66%（95%CI：0.03%‒1.30%） and 0.59%（95%CI：0.26%‒0.92%）. With the increase of PM2.5 concentration level， the impact of temperature on cardiovascular and cerebrovascular diseases gradually increased， and the impact was the most significant when the concentration of PM2.5 was more than 150 µg·m-3. There were different sensitive people in different seasons. ConclusionPM2.5 concentration levels of mild pollution and above can exacerbate the negative effects of temperature on cardiovascular and cerebrovascular diseases.
